Rein, Kathleen

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Patents issued

Antitoxins to Brevetoxin Patent

selected scholarly works & creative activities

Article
- 2021
  
  The Marine Neurotoxin Brevetoxin (PbTx-2) Inhibits Karenia brevis and Mammalian Thioredoxin Reductases by Targeting Different Residues. Journal of natural products. 84:2961-2970.
  Full Text via DOI: 10.1021/acs.jnatprod.1c00795 Web of Science: 000723680000021
- 2021
  
  Essential components of the xanthophyll cycle differ in high and low toxin Karenia brevis. Harmful Algae. 103.
  Full Text via DOI: 10.1016/j.hal.2021.102006 Web of Science: 000663075500004
- 2019
  
  Effectors of thioredoxin reductase: Brevetoxins and manumycin-A. Comparative Biochemistry and Physiology, Part C. 217:76-86.
  Full Text via DOI: 10.1016/j.cbpc.2018.11.015 Web of Science: 000463848100009
- 2018
  
  Manumycin A Is a Potent Inhibitor of Mammalian Thioredoxin Reductase-1 (TrxR-1). ACS Medicinal Chemistry Letters. 9:318-322.
  Full Text via DOI: 10.1021/acsmedchemlett.7b00489 Web of Science: 000430256200004
- 2018
  
  Brevetoxin (PbTx-2) influences the redox status and NPQ of Karenia brevis by way of thioredoxin reductase. Harmful Algae. 71:29-39.
  Full Text via DOI: 10.1016/j.hal.2017.11.004 Web of Science: 000423890200004
- 2017
  
  Toxin composition of the 2016 Microcystis aeruginosa bloom in the St. Lucie Estuary, Florida. Toxicon. 138:169-172.
  Full Text via DOI: 10.1016/j.toxicon.2017.09.005 Web of Science: 000413388300023
- 2017
  
  Brevetoxin-2, is a unique inhibitor of the C-terminal redox center of mammalian thioredoxin reductase-1. Toxicology and Applied Pharmacology. 329:58-66.
  Full Text via DOI: 10.1016/j.taap.2017.05.027 Web of Science: 000406735700007
- 2017
  
  Metabolism of okadaic acid by NADPH-dependent enzymes present in human or rat liver S9 fractions results in different toxic effects. Toxicology in Vitro. 42:161-170.
  Full Text via DOI: 10.1016/j.tiv.2017.04.009 Web of Science: 000404304900020
- 2016
  
  Differences in metabolism of the marine biotoxin okadaic acid by human and rat cytochrome P450 monooxygenases. Archives of Toxicology. 90:2025-2036.
  Full Text via DOI: 10.1007/s00204-015-1591-9 Web of Science: 000379254500019
- 2016
  
  Characterization of an epoxide hydrolase from the Florida red tide dinoflagellate, Karenia brevis. Phytochemistry. 122:11-21.
  Full Text via DOI: 10.1016/j.phytochem.2015.11.002 Web of Science: 000369460200001
- 2015
  
  Brevetoxin, the Dinoflagellate Neurotoxin, Localizes to Thylakoid Membranes and Interacts with the Light-Harvesting Complex II (LHCII) of Photosystem II. ChemBioChem. 16:1060-1067.
  Full Text via DOI: 10.1002/cbic.201402669 Web of Science: 000353502300008
- 2015
  
  Student Response to a Partial Inversion of an Organic Chemistry Course for Non-Chemistry Majors. Journal of Chemical Education. 92:797-802.
  Full Text via DOI: 10.1021/ed500537b Web of Science: 000355057300006
- 2013
  
  SUBCELLULAR LOCALIZATION OF DINOFLAGELLATE POLYKETIDE SYNTHASES AND FATTY ACID SYNTHASE ACTIVITY. Journal of Phycology. 49:1118-1127.
  Full Text via DOI: 10.1111/jpy.12120 Web of Science: 000328343400010
- 2013
  
  Diastereoselective synthesis of deprotectable isoxazolidines. Tetrahedron Letters. 54:1866-1868.
  Full Text via DOI: 10.1016/j.tetlet.2013.01.105 Web of Science: 000316095000022
- 2013
  
  Synthesis, receptor binding and activity of iso and azakainoids. Bioorganic and Medicinal Chemistry Letters. 23:1949-1952.
  Full Text via DOI: 10.1016/j.bmcl.2013.02.046 Web of Science: 000316642900006
- 2013
  
  The use of Mosher derivatives for the determination of the absolute configuration of substituted isoxazolidines. Tetrahedron: Asymmetry: the international journal for rapid publication on all aspects of asymmetry in organic, inorganic, organometallic, physical and bioorganic chemistry. 24:223-228.
  Full Text via DOI: 10.1016/j.tetasy.2013.01.016 Web of Science: 000316167800012
- 2012
  
  Biosynthesis of Athmu, a alpha,gamma-hydroxy-beta-amino acid of pahayokolides A-B. Tetrahedron Letters. 53:6758-6760.
  Full Text via DOI: 10.1016/j.tetlet.2012.09.119 Web of Science: 000311473500006
- 2012
  
  Microbial degradation of microcystin in Florida's freshwaters. Biodegradation. 23:35-45.
  Full Text via DOI: 10.1007/s10532-011-9484-y Web of Science: 000300283900004
- 2012
  
  Gene expression profiling of human liver carcinoma (HepG2) cells exposed to the marine toxin okadaic acid. Toxicological and Environmental Chemistry. 94:1805-1821.
  Full Text via DOI: 10.1080/02772248.2012.730199 Web of Science: 000310311500016
- 2011
  
  Biosynthetic Origin of the 3-Amino-2,5,7,8-tetrahydroxy-10-methylundecanoic Acid Moiety and Absolute Configuration of Pahayokolides A and B. Journal of natural products. 74:1535-1538.
  Full Text via DOI: 10.1021/np200362q Web of Science: 000291920600028
- 2010
  
  Human metabolites of brevetoxin PbTx-2: Identification and confirmation of structure. Toxicon. 56:648-651.
  Full Text via DOI: 10.1016/j.toxicon.2010.06.007 Web of Science: 000281001800021
- 2010
  
  UV and solar TiO₂ photocatalysis of brevetoxins (PbTxs). Toxicon. 55:1008-1016.
  Full Text via DOI: 10.1016/j.toxicon.2009.11.014 Web of Science: 000276436400013
- 2010
  
  The algal hepatoxoxin okadaic acid is a substrate for human cytochromes CYP3A4 and CYP3A5. Toxicon. 55:325-332.
  Full Text via DOI: 10.1016/j.toxicon.2009.08.007 Web of Science: 000274579100020
- 2010
  
  Biodegradation of polyether algal toxins-Isolation of potential marine bacteria. Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering. 45:1850-1857.
  Full Text via DOI: 10.1080/10934529.2010.520510 Web of Science: 000282970900001
- 2009
  
  Viable cell sorting of dinoflagellates by multiparametric flow cytometry. Phycologia. 48:249-257.
  Full Text via DOI: 10.2216/08-51.1 Web of Science: 000268126800003
- 2009
  
  Multiple simultaneous detection of Harmful Algal Blooms (HABs) through a high throughput bead array technology, with potential use in phytoplankton community analysis. Harmful Algae. 8:196-211.
  Full Text via DOI: 10.1016/j.hal.2008.05.003 Web of Science: 000262803800002
- 2008
  
  Diverse bacterial PKS sequences derived from okadaic acid-producing dinoflagellates. Marine Drugs. 6:164-179.
  Full Text via DOI: 10.3390/md20080009 Web of Science: 000257202100006
- 2008
  
  Allelopathic activity among Cyanobacteria and microalgae isolated from Florida freshwater habitats. FEMS Microbiology Ecology. 64:55-64.
  Full Text via DOI: 10.1111/j.1574-6941.2008.00439.x Web of Science: 000253886700006
- 2007
  
  1‐3‐Dipolar Cycloadditions of Trimethylsilyldiazomethane Revisited: Steric Demand of the Dipolarophile and the Influence on Product Distribution.. ChemInform. 38:no-no.
  Full Text via DOI: 10.1002/chin.200721105
- 2007
  
  Structures of pahayokolides A and B, cyclic peptides from a Lyngbya sp.. Journal of natural products. 70:730-735.
  Full Text via DOI: 10.1021/np060389p Web of Science: 000246764300002
- 2007
  
  1,3-dipolar cycloadditions of trimethylsilyldiazomethane revisited: Steric demand of the dipolarophile and the influence on product distribution. Journal of Organic Chemistry. 72:650-653.
  Full Text via DOI: 10.1021/jo061838t Web of Science: 000243416300046
- 2006
  
  Ultrasonically induced degradation of microcystin-LR and -RR: Identification of products, effect of pH, formation and destruction of peroxides. Environmental Science and Technology. 40:3941-3946.
  Full Text via DOI: 10.1021/es0521730 Web of Science: 000238217200045
- 2005
  
  Ultrasonically induced degradation and detoxification of microcystin-LR (cyanobacterial toxin). Environmental Science and Technology. 39:6300-6305.
  Full Text via DOI: 10.1021/es048350z Web of Science: 000231203100056
- 2005
  
  Localization of polyketide synthase encoding genes to the toxic dinoflagellate Karenia brevis. Phytochemistry. 66:1767-1780.
  Full Text via DOI: 10.1016/j.phytochem.2005.06.010 Web of Science: 000231410800003
- 2005
  
  The toxicity of microcystin LR in mice following 7 days of inhalation exposure. Toxicon. 45:691-698.
  Full Text via DOI: 10.1016/j.toxicon.2005.01.004 Web of Science: 000228686500002
- 2004
  
  Pharmacology and toxicology of pahayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the Florida Everglades. Comparative Biochemistry and Physiology, Part C. 139:231-238.
  Full Text via DOI: 10.1016/j.cca.2004.11.005 Web of Science: 000227120600008
- 2004
  
  Aza Analogues of Kainoids by Dipolar Cycloaddition.. ChemInform. 35:no-no.
  Full Text via DOI: 10.1002/chin.200437194
- 2004
  
  Aza analogs of kainoids by dipolar cycloaddition. Tetrahedron Letters. 45:4703-4705.
  Full Text via DOI: 10.1016/j.tetlet.2004.04.097 Web of Science: 000221801100025
- 2003
  
  The structural basis for kainoid selectivity at AMPA receptors revealed by low-mode docking calculations. Bioorganic and Medicinal Chemistry. 11:551-559.
  Full Text via DOI: 10.1016/S0968-0896(02)00448-0 Web of Science: 000180693900009
- 2002
  
  Are Pfiesteria species toxicogenic? Evidence against production of ichthyotoxins by Pfiesteria shumwayae. Proceedings of the National Academy of Sciences of the United States of America. 99:10970-10975.
  Full Text via DOI: 10.1073/pnas.172221699 Web of Science: 000177606900007
- 2000
  
  Brevetoxin derivatives that inhibit toxin activity. Chemistry and Biology. 7:385-393.
  Full Text via DOI: 10.1016/S1074-5521(00)00119-8 Web of Science: 000087683100004
- 1998
  
  UV-visible and inelastic electron tunneling spectroscopies of brevetoxins. Applied Spectroscopy. 52:523-527.
  Full Text via DOI: 10.1366/0003702981944067 Web of Science: 000073512700008
- 1998
  
  Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons. Journal of Pharmacology and Experimental Therapeutics. 284:516-525.
  Web of Science: 000071929100012
- 1997
  
  Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor. Archives of Biochemistry and Biophysics. 343:149-156.
  Full Text via DOI: 10.1006/abbi.1997.0149 Web of Science: A1997XL43100001
- 1996
  
  Assessment of methods for the determination of ciguatoxins. Toxicon. 34:306.
  Full Text via DOI: 10.1016/0041-0101(96)80918-4
- 1995
  
  THE RELATIONSHIP OF BREVETOXIN LENGTH AND A-RING FUNCTIONALITY TO BINDING AND ACTIVITY IN NEURONAL SODIUM-CHANNELS. Chemistry and Biology. 2:533-541.
  Full Text via DOI: 10.1016/1074-5521(95)90187-6 Web of Science: A1995RR27500006
- 1995
  
  BREVETOXIN-3 - TOTAL ASSIGNMENT OF THE H-1 AND C-13 NMR-SPECTRA AT THE SUBMICROMOLE LEVEL. Tetrahedron. 51:8409-8422.
  Full Text via DOI: 10.1016/0040-4020(95)00360-K Web of Science: A1995RL91100003
- 1994
  
  ChemInform Abstract: Brevetoxin B: Chemical Modifications, Synaptosome Binding, Toxicity, and an Unexpected Conformational Effect.. ChemInform. 25:no-no.
  Full Text via DOI: 10.1002/chin.199439282
- 1994
  
  ChemInform Abstract: Conformational Analysis of the Sodium Channel Modulator, Brevetoxin A, Comparison with Brevetoxin B Conformations, and a Hypothesis About the Common Pharmacophore of the “Site 5” Toxins.. ChemInform. 25:no-no.
  Full Text via DOI: 10.1002/chin.199439281
- 1994
  
  BREVETOXIN-PBTX-2 IMMUNOLOGY - DIFFERENTIAL EPITOPE RECOGNITION BY ANTIBODIES FROM 2 GOATS. Toxicon. 32:883-890.
  Full Text via DOI: 10.1016/0041-0101(94)90367-0 Web of Science: A1994PA94100004
- 1994
  
  BREVETOXIN-B - CHEMICAL MODIFICATIONS, SYNAPTOSOME BINDING, TOXICITY, AND AN UNEXPECTED CONFORMATIONAL EFFECT. Journal of Organic Chemistry. 59:2107-2113.
  Full Text via DOI: 10.1021/jo00087a028 Web of Science: A1994NJ13700028
- 1994
  
  CONFORMATIONAL-ANALYSIS OF THE SODIUM-CHANNEL MODULATOR, BREVETOXIN-A, COMPARISON WITH BREVETOXIN-B CONFORMATIONS, AND A HYPOTHESIS ABOUT THE COMMON PHARMACOPHORE OF THE SITE-5 TOXINS. Journal of Organic Chemistry. 59:2101-2106.
  Full Text via DOI: 10.1021/jo00087a027 Web of Science: A1994NJ13700027
- 1994
  
  Is the A‐ring lactone of brevetoxin PbTX‐3 required for sodium channel orphan receptor binding and activity?. Natural Toxins. 2:212-221.
  Full Text via DOI: 10.1002/nt.2620020410
- 1992
  
  ChemInform Abstract: Single Electron Transfer in the Addition of Chiral Dipole‐Stabilized Organolithiums to Carbonyls. Stereochemistry of a Chiral Nucleophile as a Mechanistic Probe.. ChemInform. 23:no-no.
  Full Text via DOI: 10.1002/chin.199205066
- 1991
  
  ChemInform Abstract: Analysis of (α‐Hydroxybenzyl)tetrahydroisoquinoline Stereoisomers by Pirkle Column HPLC: Correlation of Absolute Configuration with Order of Elution.. ChemInform. 22:no-no.
  Full Text via DOI: 10.1002/chin.199131300
- 1991
  
  SINGLE ELECTRON-TRANSFER IN THE ADDITION OF CHIRAL DIPOLE-STABILIZED ORGANOLITHIUMS TO CARBONYLS - STEREOCHEMISTRY OF A CHIRAL NUCLEOPHILE AS A MECHANISTIC PROBE. Tetrahedron Letters. 32:1941-1944.
  Full Text via DOI: 10.1016/0040-4039(91)85007-R Web of Science: A1991FG50000006
- 1991
  
  SYNTHESIS OF THE PHTHALIDE ISOQUINOLINE ALKALOIDS (-)-EGENINE, (-)-CORYTENSINE, AND (-)-BICUCULLINE BY ASYMMETRIC CARBONYL ADDITION OF CHIRAL DIPOLE-STABILIZED ORGANOMETALLICS. Journal of Organic Chemistry. 56:1564-1569.
  Full Text via DOI: 10.1021/jo00004a041 Web of Science: A1991EY47600041
- 1990
  
  SYNTHESIS OF (-)-EGENINE (DECUMBENSINE) BY ASYMMETRIC CARBONYL ADDITION. Tetrahedron Letters. 31:3711-3714.
  Full Text via DOI: 10.1016/S0040-4039(00)97451-3 Web of Science: A1990DL87800014
- 1989
  
  ChemInform Abstract: Acyclic Stereoselection in the Alkylation of Chiral Dipole‐Stabilized Organolithiums: A Self‐Immolative Chirality Transfer Process for the Synthesis of Primary Amines.. ChemInform. 20:no-no.
  Full Text via DOI: 10.1002/chin.198948124
- 1989
  
  ChemInform Abstract: Chiral Dipole‐Stabilized Anions: Experimental and Theory in Benzylic and Allylic Systems. Stereoselective Deprotonations, Pyramidal Inversions, and Stereoselective Alkylations of Lithiated (Tetrahydroisoquinolyl)oxazolines.. ChemInform. 20:no-no.
  Full Text via DOI: 10.1002/chin.198926065
- 1989
  
  CHIRAL DIPOLE-STABILIZED ANIONS - EXPERIMENT AND THEORY IN BENZYLIC AND ALLYLIC SYSTEMS - STEREOSELECTIVE DEPROTONATIONS, PYRAMIDAL INVERSIONS, AND STEREOSELECTIVE ALKYLATIONS OF LITHIATED (TETRAHYDROISOQUINOLYL)OXAZOLINES. Journal of the American Chemical Society. 111:2211-2217.
  Full Text via DOI: 10.1021/ja00188a040 Web of Science: A1989T780200040
- Identification of okadaic acid production in the marine dinoflagellate Prorocentrum rhathymum from Florida Bay. Toxicon. 55:653-657.
  Full Text via DOI: 10.1016/j.toxicon.2009.08.018 Web of Science: 000274579100062
- Low-mode docking search in iGluR homology models implicates three residues in the control of ligand selectivity. Journal of Molecular Recognition. 18:183-189.
  Full Text via DOI: 10.1002/jmr.713 Web of Science: 000227704400007
- MODIFIED IMMUNOASSAYS FOR POLYETHER TOXINS - IMPLICATIONS OF BIOLOGICAL MATRICES, METABOLIC STATES, AND EPITOPE RECOGNITION. Journal of AOAC International. 78:499-508.
  Web of Science: A1995QN30400038
- Polyketide synthase genes from marine dinoflagellates. Marine Biotechnology. 5:1-12.
  Full Text via DOI: 10.1007/s10126-002-0077-y Web of Science: 000181333200001
- RADIOIMMUNOASSAY FOR PBTX-2-TYPE BREVETOXINS - EPITOPE SPECIFICITY OF 2 ANTI-PBTX SERA. Journal of AOAC International. 78:538-542.
  Web of Science: A1995QN30400044
Book Chapter
- 1998
  
  Marine Toxins: How They are Studied and What They Can Tell Us. 487-514.
  Full Text via DOI: 10.1007/978-94-011-4928-0_26
- 1991
  
  1.2 Alkylations of Nitrogen-stabilized Carbanions. 65-83.
  Full Text via DOI: 10.1016/b978-0-08-052349-1.00059-7
- 1991
  
  2.1 Nitrogen Stabilization. 459-485.
  Full Text via DOI: 10.1016/b978-0-08-052349-1.00014-7
Conference
- 2019
  
  Brevetoxin is an effector of mammalian thioredoxin reductase (TrxR). ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000478861200713
- 2013
  
  Black band disease (BBD): Pigment characterization and reactive oxygen species (ROS) production and evolution assay development. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000323851302112
- 2008
  
  Ultrasonically-induced degradation of microcystin LR and RR: Identification of byproducts and effect of environmental factors. Advances in Experimental Medicine and Biology. 305-306.
  Web of Science: 000254893200028
- 2007
  
  1, 3-Dipolar cycloadditons of TMS diazomethane revisited. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000207722808137
- 2005
  
  Mechanistic study of ultrasonic irradiation of microcystin-LR. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U834-U834.
  Web of Science: 000228177706051
- 2004
  
  Photodegradation and oxidation of microcystin.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U625-U625.
  Web of Science: 000223655602114
- 2004
  
  Syntheses of aza analogs of kainoids. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U138-U138.
  Web of Science: 000223655700720
- 2004
  
  Ultrasound treatment of cyantoxin microcystin-LR. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U1058-U1058.
  Web of Science: 000223655603620
- 2002
  
  Is Pfiesteria toxigenic? Chemical and molecular evidence against polyketide and non-ribosomal peptide toxin production by Pfiesteria shumwayae.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. B232-B232.
  Web of Science: 000176296801295
- 2002
  
  Low-mode conformational search of kainic acid in homology models of non-NMDA receptors.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U223-U223.
  Web of Science: 000176296701160
- 2002
  
  Low-mode conformational search of kanoids in the AMPA receptor: The basis of kanoid selectivity.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U223-U223.
  Web of Science: 000176296701161
- 2001
  
  Synthesis of kainic acid analogs.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U151-U151.
  Web of Science: 000168824701283
- 1995
  
  MECHANISM OF INDUCTION OF CYTOCHROME P4501A BY BREVETOXIN (PBTX), A POLYETHER MARINE NEUROTOXIN. The FASEB Journal. A714-A714.
  Web of Science: A1995QM40600517
- 1994
  
  BREVETOXIN-3 (PBTX-3) AND ITS DERIVATIVES MODULATE SINGLE SODIUM-CHANNELS IN RAT SENSORY NEURONS. Biophysical Journal. A323-A323.
  Web of Science: A1994MU46201877
- 1992
  
  COMPUTATIONAL MODELING OF THE POLYETHER LADDER TOXINS BREVETOXIN AND CIGUATOXIN. 103-114.
  Web of Science: A1992BX60R00010
Letter
- 1989
  
  ACYCLIC STEREOSELECTION IN THE ALKYLATION OF CHIRAL DIPOLE-STABILIZED ORGANOLITHIUMS - A SELF-IMMOLATIVE CHIRALITY TRANSFER PROCESS FOR THE SYNTHESIS OF PRIMARY AMINES. Journal of Organic Chemistry. 3002-3004.
  Full Text via DOI: 10.1021/jo00274a004 Web of Science: A1989AC85000004
Note
- 1992
  
  BINDING OF BREVETOXINS AND CIGUATOXIN TO THE VOLTAGE-SENSITIVE SODIUM-CHANNEL AND CONFORMATIONAL-ANALYSIS OF BREVETOXIN-B. Toxicon. 780-785.
  Full Text via DOI: 10.1016/0041-0101(92)90014-V Web of Science: A1992JD02000014
- 1991
  
  ANALYSIS OF (ALPHA-HYDROXYBENZYL)TETRAHYDROISOQUINOLINE STEREOISOMERS BY PIRKLE COLUMN HPLC - CORRELATION OF ABSOLUTE-CONFIGURATION WITH ORDER OF ELUTION. Journal of Organic Chemistry. 839-841.
  Full Text via DOI: 10.1021/jo00002a062 Web of Science: A1991EU10800062
Other Scholarly Work
- 2014
  
  In vivo demonstration of okadaic acid internalization in glutamatergic spinal motor neurons. The FASEB Journal.
  Web of Science: 000346651000350
Review
- 2010
  
  New Peptides Isolated from Lyngbya Species: A Review. Marine Drugs. 1817-1837.
  Full Text via DOI: 10.3390/md8061817 Web of Science: 000280347000008
- 2006
  
  The biosynthesis of polyketide metabolites by dinoflagellates. Advances in Applied Microbiology. 93-125.
  Full Text via DOI: 10.1016/S0065-2164(06)59004-5 Web of Science: 000239588000004
- 1999
  
  Polyketides from dinoflagellates: origins, pharmacology and biosynthesis. Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 117-131.
  Full Text via DOI: 10.1016/S0305-0491(99)00107-8 Web of Science: 000082764400001
- 1992
  
  Methods for detecting brevetoxins in seawater, in biological matrices, and on excitable membranes.. Bulletin de la Societe de Pathologie Exotique. 516-518.

principal investigator on

A Mechanism Based Intervention for Brevetoxin Induced Oxidative Stress awarded by National Oceanic and Atmospheric Admin 2018 - 2022
Red Tide Initiative awarded by nTEC Solutions LLC 2021 - 2022
Bridge Funding - Chemistry Lab awarded by FIU Office of Research and Economic Deve 2012 - 2014
Advanced Research Cooperation in Environmental Health (ARCH)/Admin Supplement awarded by Environmental Health Sciences 2011 - 2012
Advanced Research Cooperation in Environmental Health Research awarded by Environmental Health Sciences 2010 - 2012
COHH Toxic Algae Project awarded by National Science Foundation 2009 - 2011
A Proposal for the Synthesis of Putative Salmeterol Degradation Product awarded by Teva Pharmaceuticals 2009 - 2010
Advanced Research Cooperation in Environmental Health Research awarded by Environmental Health Sciences 2009 - 2010
Toxic Algae. awarded by National Science Foundation 2004 - 2010
Oceans and Human Health Toxic Algae Facility Core. awarded by Environmental Health Sciences 2008 - 2009
Advance Research Cooperation in Environmental Health (ARCH). awarded by Environmental Health Sciences 2008 - 2009
Advanced Research Cooperation in Environmental Health (ARCH). awarded by Environmental Health Sciences 2007 - 2009
Synthesis of Impurity D from Salmeterol. awarded by Teva Pharmaceuticals 2008 - 2009

co-principal investigator on

Grant
- Biscayne Bay PhycoNet: a monitoring network and database capturing the biological and biochemical diversity of phytoplankton for the rapid detection of toxic bloom-forming taxa awarded by National Oceanic and Atmospheric Admin 2022 - 2026
- Collaborative for Instiutionalizing Scientific Learning at FIU awarded by Howard Hughes Medical Institute 2014 - 2021
- Advanced Research Cooperation in Environmental Health Research awarded by Environmental Health Sciences 2010 - 2012
- Advanced Research Cooperation in Environmental Health Research awarded by Environmental Health Sciences 2009 - 2010

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Co-investigator Network