Moon, Joongho

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Moon, Joongho Graduate Faculty

Positions

Professor, Chemistry and Biochemistry , College of Arts, Sciences & Education

jmoon@fiu.edu

Intellectual Property

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overview

Dr. Moon received his Ph.D. in Inorganic and Materials Chemistry from Pohang University of Science and Technology in August 1999, where he studied surface modifications and characterizations. At MIT, Dr. Moon studied the conjugated polymer brushes and the effect of unique surface structures on chemical sensing under Prof. Tim Swager. After seven-year industrial research experience, Dr. Moon joined the Department of Chemistry at FIU. His current research focuses on the development of novel fluorescent materials for sensitive and reliable detection of target molecules and substances.

Patents issued

selected scholarly works & creative activities

Article
- 2026
  
  Amphiphilic Phenyl Carbamoyl Guanidine-Modified ε-Poly-l-Lysine Enables Efficient Intracellular Antibody Delivery. Biomacromolecules.
  Full Text via DOI: 10.1021/acs.biomac.5c02420 Web of Science: 001715778600001
- 2025
  
  Effect of conjugation length on conjugated polymer-mediated intracellular protein delivery. Macromolecular Research. 33:643-654.
  Full Text via DOI: 10.1007/s13233-024-00360-9 Web of Science: 001413576900001
- 2025
  
  Enhanced Intracellular Protein Activity by Caveolae-Mediated Endocytosis of Conjugated Polymer/Protein Complexes. Macromolecular Bioscience. 25.
  Full Text via DOI: 10.1002/mabi.202400557 Web of Science: 001413862500001
- 2022
  
  Proton Motive Force-Disrupting Antimycobacterial Guanylurea Polymer. Biomacromolecules. 23:4668-4677.
  Full Text via DOI: 10.1021/acs.biomac.2c00902 Web of Science: 000884681200001
- 2022
  
  Effects of sidechain isomerism on polymer-based non-covalent protein delivery. Chemical Communications. 58:8246-8249.
  Full Text via DOI: 10.1039/d2cc02343a Web of Science: 000820390400001
- 2022
  
  Potentiometric and SERS Detection of Single Nanoparticle Collision Events on a Surface Functionalized Gold Nanoelectrode. Journal of the Electrochemical Society. 169.
  Full Text via DOI: 10.1149/1945-7111/ac6245 Web of Science: 000780481500001
- 2022
  
  Carbamoylated Guanidine-Containing Polymers for Non-Covalent Functional Protein Delivery in Serum-Containing Media. Angewandte Chemie International Edition. 61.
  Full Text via DOI: 10.1002/anie.202116722 Web of Science: 000744709300001
- 2022
  
  Carbamoylated Guanidine‐Containing Polymers for Non‐Covalent Functional Protein Delivery in Serum‐Containing Media. Angewandte Chemie International Edition. 134.
  Full Text via DOI: 10.1002/ange.202116722
- 2021
  
  Searching for solar KDAR with DUNE. Journal of Cosmology and Astroparticle Physics.
  Full Text via DOI: 10.1088/1475-7516/2021/10/065 Web of Science: 000758221400019
- 2019
  
  A guanylurea-functionalized conjugated polymer enables RNA interference in ex vivo human airway epithelium. Chemical Communications. 55:7804-7807.
  Full Text via DOI: 10.1039/c9cc02856k Web of Science: 000474265200015
- 2019
  
  Phenyleneethynylene trimer-based rigid-flexible [2+2] macrocycles for nucleic acid labelling in live cells. Chemical Communications. 55:5930-5933.
  Full Text via DOI: 10.1039/c9cc02162k Web of Science: 000468478100018
- 2019
  
  Extracellular Surface Potential Mapping by Scanning Ion Conductance Microscopy Revealed Transient Transmembrane Pore Formation Induced by Conjugated Polymer Nanoparticles. Macromolecular Bioscience. 19.
  Full Text via DOI: 10.1002/mabi.201800271 Web of Science: 000458369000003
- 2018
  
  Controlled ionic complexation of positively charged phenylene-based conjugated polymers by modulated backbone structures. Polymer International. 67:1629-1637.
  Full Text via DOI: 10.1002/pi.5686 Web of Science: 000449675300005
- 2018
  
  Synthesis of Antimicrobial Poly(guanylurea)s. Bioconjugate Chemistry. 29:1006-1009.
  Full Text via DOI: 10.1021/acs.bioconjchem.8b00057 Web of Science: 000430641700020
- 2017
  
  Amide-based oligomers for low-viscosity composites of polyamide 66. Macromolecular Research. 25:1000-1006.
  Full Text via DOI: 10.1007/s13233-017-5129-2 Web of Science: 000414234200007
- 2016
  
  Scanning Ion Conductance Microscopic Study for Cellular Uptake of Cationic Conjugated Polymer Nanoparticles. Macromolecular Bioscience. 16:599-607.
  Full Text via DOI: 10.1002/mabi.201500320 Web of Science: 000374262100012
- 2016
  
  Mitochondria-specific conjugated polymer nanoparticles. Chemical Communications. 52:4910-4913.
  Full Text via DOI: 10.1039/c6cc00810k Web of Science: 000373061300014
- 2015
  
  Synthesis of Biodegradable Conjugated Polymers with Controlled Backbone Flexibility. Journal of Polymer Science. 53:1403-1412.
  Full Text via DOI: 10.1002/pola.27622 Web of Science: 000353342700012
- 2015
  
  Differential interactions of conjugated polymer nanoparticles with glycosaminoglycans in synthetic urine. Chemical Communications. 51:4065-4068.
  Full Text via DOI: 10.1039/c5cc00110b Web of Science: 000350212600027
- 2014
  
  Sensors Research at the NSF-Assist Nanosystems Engineering Research Center:Correlated Sensing of Environmental and Physiological Parameters Using Low-Power Wearable Sensors. ECS Meeting Abstracts. MA2014-01:454-454.
  Full Text via DOI: 10.1149/ma2014-01/6/454
- 2013
  
  Regioselective One-Pot Synthesis of Isocoumarins and Phthalides from 2-Iodobenzoic Acids and Alkynes by Temperature Control. Advanced Synthesis and Catalysis. 355:3221-3230.
  Full Text via DOI: 10.1002/adsc.201300561 Web of Science: 000328321400015
- 2013
  
  Fabrication of Core-Shell Nanoparticles via Controlled Aggregation of Semiflexible Conjugated Polymer and Hyaluronic Acid. Macromolecules. 46:6374-6378.
  Full Text via DOI: 10.1021/ma400996y Web of Science: 000323193300063
- 2013
  
  Caveolae-Mediated Endocytosis of Conjugated Polymer Nanoparticles. Macromolecular Bioscience. 13:913-920.
  Full Text via DOI: 10.1002/mabi.201300030 Web of Science: 000327814500010
- 2013
  
  Synthesis of Poly(phenylenebutadiynylenes) Using the Decarboxylative Coupling of Propiolic Acid and Aryl Iodides. Synlett. 24:1563-1567.
  Full Text via DOI: 10.1055/s-0033-1339189 Web of Science: 000321610300020
- 2013
  
  Synthesis of Phenyleneethynylene-Doped Poly(p-phenylenebutadiynylene)s for Live Cell Imaging. Macromolecules. 46:1253-1259.
  Full Text via DOI: 10.1021/ma3019975 Web of Science: 000315018400075
- 2013
  
  Side chain and backbone structure-dependent subcellular localization and toxicity of conjugated polymer nanoparticles. Chemical Communications. 49:6048-6050.
  Full Text via DOI: 10.1039/c3cc43015d Web of Science: 000320199000013
- 2012
  
  3D-resolved fluorescence and phosphorescence lifetime imaging using temporal focusing wide-field two-photon excitation. Optics Express. 20:26219-26235.
  Full Text via DOI: 10.1364/OE.20.026219 Web of Science: 000312452800013
- 2011
  
  Controlled Aggregation in Conjugated Polymer Nanoparticles via Organic Acid Treatments. Macromolecules. 44:5527-5530.
  Full Text via DOI: 10.1021/ma200661h Web of Science: 000292417800055
- 2011
  
  Conjugated polymer nanoparticles for small interfering RNA delivery. Chemical Communications. 47:8370-8372.
  Full Text via DOI: 10.1039/c1cc10991j Web of Science: 000292980900052
- 2010
  
  Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts. BMC Plant Biology. 10.
  Full Text via DOI: 10.1186/1471-2229-10-291 Web of Science: 000286434300001
- 2010
  
  Conjugated Polymer Nanoparticles for Fluorescent Labeling of Live Cells and Delivery of Biological Molecules into Plant Cells. Microscopy and Microanalysis. 16:1796-1797.
  Full Text via DOI: 10.1017/s1431927610061726
- 2009
  
  Conjugated Polymer Nanoparticles for Two-Photon Imaging of Endothelial Cells in a Tissue Model. Advanced Materials. 21:3492-+.
  Full Text via DOI: 10.1002/adma.200900416 Web of Science: 000270380100007
- 2008
  
  ChemInform Abstract: One‐Pot Synthesis of Diarylalkynes Using Palladium‐Catalyzed Sonogashira Reaction and Decarboxylative Coupling of sp Carbon and sp2 Carbon.. ChemInform. 39:no-no.
  Full Text via DOI: 10.1002/chin.200832095
- 2008
  
  One-pot synthesis of diarylalkynes using palladium-catalyzed Sonogashira reaction and decarboxylative coupling of sp carbon and sp² carbon. Organic Letters. 10:945-948.
  Full Text via DOI: 10.1021/ol703130y Web of Science: 000253519600066
- 2007
  
  Conjugated polymer nanoparticles for biochemical protein kinase assay. Chemical Communications. 4910-4912.
  Full Text via DOI: 10.1039/b710807a Web of Science: 000251678300023
- 2007
  
  Live-cell-permeable poly (p-phenylene ethynylene). Angewandte Chemie International Edition. 46:8223-8225.
  Full Text via DOI: 10.1002/anie.200701991 Web of Science: 000250966100025
- 2006
  
  Facile fabrication of poly(p-phenylene ethynylene)/colloidal silica composite for nucleic acid detection. Journal of Colloid and Interface Science. 300:117-122.
  Full Text via DOI: 10.1016/j.jcis.2006.03.063 Web of Science: 000238877700015
- 2003
  
  Capture and detection of a quencher labeled oligonucleotide by poly(phenylene ethynylene) particles. Chemical Communications. 104-105.
  Full Text via DOI: 10.1039/b207186j Web of Science: 000180001200047
- 2002
  
  Poly(p-phenylene ethynylene) brushes. Macromolecules. 35:6086-6089.
  Full Text via DOI: 10.1021/ma025539r Web of Science: 000177090400006
- 2000
  
  A hyperbranched poly(ethyleneimine) grown on surfaces. Journal of Colloid and Interface Science. 227:247-249.
  Full Text via DOI: 10.1006/jcis.2000.6861 Web of Science: 000087902900032
- 2000
  
  Selective cleavage of the carbon-halide bond in substituted benzaldimine monolayers by synchrotron soft X-ray: Anomalously large cleavage rate of the carbon-bromide bond. Langmuir. 16:2981-2984.
  Full Text via DOI: 10.1021/la991061h Web of Science: 000085984500082
- 1997
  
  Absolute surface density of the amine group of the aminosilylated thin layers: Ultraviolet-visible spectroscopy, second harmonic generation, and synchrotron-radiation photoelectron spectroscopy study. Langmuir. 13:4305-4310.
  Full Text via DOI: 10.1021/la9705118 Web of Science: A1997XP79300020
- 1997
  
  Self-Assembly of Aminosilane Layers: Determination of Surface Density of the Amine Group Through a Reversible Chemical Reaction. Molecular Crystals and Liquid Crystals. 295:185-188.
  Full Text via DOI: 10.1080/10587259708042826
- 1996
  
  Self-assembly of non-linear optical chromophores through ionic interactions. Journal of Materials Chemistry. 6:365-368.
  Full Text via DOI: 10.1039/jm9960600365 Web of Science: A1996UC40000015
Book Chapter
- 2018
  
  Conjugated Polymers for Gene Delivery. 215-241.
  Full Text via DOI: 10.1002/9783527342747.ch8
Conference
- 2019
  
  Structure-activity relationship studies of antimicrobial poly-(guanylurea) for overcoming drug resistance. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000525061505190
- 2019
  
  Guanylurea-functionalized conjugated polymers for efficient gene knockdown in normal human bronchial epithelium cells. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000478861205559
- 2019
  
  Transient membrane pore-forming conjugated polymer nanoparticles. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000478860504392
- 2018
  
  Synthesis of antimicrobial poly(guanylurea)s. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000447609105320
- 2018
  
  Antimicrobial amidinourea polymers for treating drug resistance bacteria. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000435537706385
- 2018
  
  Conjugated polymers for RNA interference in human primary bronchial cells. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000435539907248
- 2017
  
  Chiral self-assembly of achiral pi-conjugated polyelectrolytes induced by hyaluronic acid. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000430569106786
- 2017
  
  Degradable conjugated polymers: New biomaterials for biological labeling, sensing, and delivery. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000430569108511
- 2017
  
  Synthesis of fluorescent phenyleneethynylene trimer-containing polymer. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000430569107177
- 2016
  
  Backbone-dependent, self-assembly behaviors of phenylene-based, cationic conjugated polymers. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000431905706243
- 2016
  
  Conjugated polymer nanoparticles for improved, peptide-mediated drug delivery. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000431905705836
- 2015
  
  Cellular toxicity and uptake behavior of triphenyl phosphonium-containing conjugated polymer nanoparticles. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000411186504589
- 2015
  
  Conjugated polymer nanoparticles for intracellular organelle specific drug delivery. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000411186504276
- 2015
  
  Synthesis of biodegradable conjugated polymers with controlled backbone flexibility. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000411186505025
- 2014
  
  Engineered conjugated polymer nanoparticles for glycosaminoglycan profiling in a urine simulant. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000349165103838
- 2013
  
  Conjugated polymer nanoparticles for cellular delivery and imaging applications. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000329618406756
- 2010
  
  Aggregation control of poly(p-phenylene ethynylene)s in water for biological imaging applications. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000208164706345
- 2009
  
  Super bright conjugated polymer nanoparticles for long-term cell tracking. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000207857807161
- 2008
  
  PMSE 17-Conjugated polymer nanoparticles for live cell imaging. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000271775109118
- 2003
  
  Stem-loop oligonucleotide beacons as switches for amplifying fluorescent polymer based biological warfare sensors. Proceedings of SPIE - The International Society for Optical Engineering. 272-279.
  Full Text via DOI: 10.1117/12.502466 Web of Science: 000186496400030
- 2002
  
  Oligonucleotide detection with amplifying fluorescent polymer particles.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U433-U433.
  Web of Science: 000177422302294
- 2002
  
  Selective cleavage of functional groups in the functionalized organic monolayers by synchrotron soft X-rays. Surface Review and Letters. 305-311.
  Full Text via DOI: 10.1142/S0218625X02002233 Web of Science: 000177754500046
- 2002
  
  Oligonucleotide detection with amplifying fluorescent polymer particles. Papers presented at the ... meeting. American Chemical Society. Division of Polymer Chemistry. 764-765.
- 1997
  
  Self-assembly of aminosilane layers: Determination of surface density of the amine group through a reversible chemical reaction. Molecular Crystals and Liquid Crystals. 483-486.
  Web of Science: A1997XK48000118
- 1995
  
  SELF-ASSEMBLY OF NONLINEAR-OPTICAL CHROMOPHORIC LAYERS THROUGH THE IONIC INTERACTION. Synthetic Metals. 1729-1730.
  Full Text via DOI: 10.1016/0379-6779(94)03025-2 Web of Science: A1995QT32600083
Letter
- 1998
  
  Selective cleavage of the nitro group from a nitrophenyl monolayer by synchrotron soft X-ray. Langmuir. 5673-5675.
  Full Text via DOI: 10.1021/la980349o Web of Science: 000076221800004
- 1996
  
  Formation of uniform aminosilane thin layers: An imine formation to measure relative surface density of the amine group. Langmuir. 4621-4624.
  Full Text via DOI: 10.1021/la9604339 Web of Science: A1996VL05900004
Other Scholarly Work
- 2002
  
  Amplifying fluorescent polymer detection of bioanalytes. Proceedings of SPIE - The International Society for Optical Engineering. 78-82.
  Full Text via DOI: 10.1117/12.456910 Web of Science: 000176067200008
Preprint
- 2021
  
  Searching for solar KDAR with DUNE

principal investigator on

Poly-conjugated oligomers for noninvasive functional protein delivery awarded by National Science Foundation 2021 - 2024
CAREER: Self-assembled Biodegradable Conjugated Polymers for RNA Interference awarded by National Science Foundation 2014 - 2022
Evaluation of antimicrobial polymer in Colgate formulations awarded by Colgate-Palmolive Company 2020 - 2021
Development of 35% lightweight CCB module for automotives using highly impregnated nylon based LFT composites awarded by Korea Evaluation Inst of Industrial Tech 2014 - 2019
Multiphoton Probes for Biomedical Imaging awarded by General Medical Sciences 2011 - 2016

investigator on

Advanced Self-Powered Systems of Integrated Sensor Technologies (ASSIST) awarded by National Science Foundation 2012 - 2023
Novel Polymeric nanoparticles for drug delivery applications awarded by National Cancer Institute 2013 - 2016

full name

Joongho Moon

visualizations

Co-author Network

Co-investigator Network