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Variants of the Ebola virus matrix protein VP40 have differential effects on oligomerization and plasma membrane interactions. 301. 2025
Restricted human CD45 isoglycoforms serve as functional E-selectin ligands and delineate hematopoietic maturity. 301. 2025
Hepatic glutamic-oxaloacetic transaminase promotes mitochondrial respiration energized at complex II and alters whole body metabolism. 301. 2025
Novel mechanism of cyclic nucleotide crosstalk mediated by PKG-dependent proteasomal degradation of the Hsp90 client protein phosphodiesterase 3A. 300. 2024
Minor electrostatic changes robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles. 300. 2024
Macromolecular crowding potently stimulates DNA supercoiling activity of Mycobacterium tuberculosis DNA gyrase. 299. 2023
Plasmodium parasitophorous vacuole membrane protein Pfs16 promotes malaria transmission by silencing mosquito immunity. 299. 2023
Nitration of protein kinase G-Iα modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: Implications for acute lung injury. 297. 2021
Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover. 295:14153-14163. 2020
Protamines from liverwort are produced by post-translational cleavage and C-terminal di-aminopropanelation of several male germ-specific H1 histones. 294:16364-16373. 2019
Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1. 293:11433-11446. 2018
Distinct human (1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells. 293:7300-7314. 2018
Membrane-embedded substrate recognition by cytochrome P450 3A4. 293:4037-4046. 2018
A cationic, C-terminal patch and structural rearrangements in Ebola virus matrix VP40 protein control its interactions with phosphatidylserine. 293:3335-3349. 2018
Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence. 293:1794-1809. 2018
ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage. 293:984-994. 2018
Transient and dynamic DNA supercoiling potently stimulates the leu-500 promoter in Escherichia coli. 292:14566-14575. 2017
The fibrinogen-like domain of FREP1 protein is a broad-spectrum malaria transmission-blocking vaccine antigen. 292:11960-11969. 2017
Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry. 292:6108-6122. 2017
Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. 291:27187-27203. 2016
A Method for Multiplexed Measurement of Mitochondrial Pyruvate Carrier Activity. 291:7409-7417. 2016
Exosomes from HIV-1-infected Cells Stimulate Production of Pro-inflammatory Cytokines through Trans-activating Response (TAR) RNA. 291:1251-1266. 2016
Nitration of Hsp90 on Tyrosine 33 Regulates Mitochondrial Metabolism. 290:19055-19066. 2015
Anopheles Midgut FREP1 Mediates Plasmodium Invasion. 290:16490-16501. 2015
COPS5 Protein Overexpression Increases Amyloid Plaque Burden, Decreases Spinophilin-immunoreactive Puncta, and Exacerbates Learning and Memory Deficits in the Mouse Brain. 290:9299-9309. 2015
Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Quorum-sensing Molecule N-(3-Oxododecanoyl)-homoserine Lactone. 290:7247-7258. 2015
Evidence for an Elevated Aspartate pK_a in the Active Site of Human Aromatase. 290:1186-1196. 2015
Novel Peptide for Attenuation of Hyperoxia-induced Disruption of Lung Endothelial Barrier and Pulmonary Edema via Modulating Peroxynitrite Formation. 289:33355-33363. 2014
Modulation of the Voltage-gated Potassium Channel (Kv4.3) and the Auxiliary Protein (KChIP3) Interactions by the Current Activator NS5806. 289:32201-32213. 2014
Nitration of Tyrosine 247 Inhibits Protein Kinase G-1α Activity by Attenuating Cyclic Guanosine Monophosphate Binding. 289:7948-7961. 2014
Lipopolysaccharide- induced Lung Injury Involves the Nitration- mediated Activation of RhoA*. 289:4710-4722. 2014
COPS5 (Jab1) Protein Increases β Site Processing of Amyloid Precursor Protein and Amyloid β Peptide Generation by Stabilizing RanBP9 Protein Levels. 288:26668-26677. 2013
Asymmetric Dimethylarginine Induces Endothelial Nitric-oxide Synthase Mitochondrial Redistribution through the Nitration-mediated Activation of Akt1. 288:6212-6226. 2013
Blocking c-Jun N-terminal Kinase (JNK) Translocation to the Mitochondria Prevents 6-Hydroxydopamine-induced Toxicity in Vitro and in Vivo. 288:1079-1087. 2013
Cigarette Smoke Induces MUC5AC Protein Expression through the Activation of Sp1. 287:27948-27958. 2012
Functional RNA Interference (RNAi) Screen Identifies System A Neutral Amino Acid Transporter 2 (SNAT2) as a Mediator of Arsenic-induced Endoplasmic Reticulum Stress. 287:6025-6034. 2012
Nitroalkenes Confer Acute Cardioprotection via Adenine Nucleotide Translocase 1. 287:3573-3580. 2012
Efflux Permease CgAcr3-1 of Corynebacterium glutamicum Is an Arsenite-specific Antiporter. 287:723-735. 2012
Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire of N- and O-Glycans without Direct Incorporation. 286:21717-21731. 2011
The Strictly Conserved Arg-321 Residue in the Active Site of Escherichia coli Topoisomerase I Plays a Critical Role in DNA Rejoining. 286:18673-18680. 2011
Inactivation and Reactivation of the Mitochondrial α-Ketoglutarate Dehydrogenase Complex. 286:17640-17648. 2011
Mitochondrial c-Jun N-terminal Kinase (JNK) Signaling Initiates Physiological Changes Resulting in Amplification of Reactive Oxygen Species Generation. 286. 2011
Inhibitory Phosphorylation of GSK-3 by CaMKII Couples Depolarization to Neuronal Survival. 285:41122-41134. 2010
Cu, Zn-Superoxide Dismutase Increases Toxicity of Mutant and Zinc-deficient Superoxide Dismutase by Enhancing Protein Stability. 285:33885-33897. 2010
A Novel Function of Sphingosine Kinase 1 Suppression of JNK Activity in Preventing Inflammation and Injury. 285:15848-15857. 2010
Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1. 285:11740-11752. 2010
Properties of Arsenite Efflux Permeases (Acr3) from Alkaliphilus metalliredigens and Corynebacterium glutamicum. 284:19887-19895. 2009
Regulation of Heparan Sulfate and Chondroitin Sulfate Glycosaminoglycan Biosynthesis by 4-Fluoro-glucosamine in Murine Airway Smooth Muscle Cells. 284:16832-16839. 2009
Novel Role of RanBP9 in BACE1 Processing of Amyloid Precursor Protein and Amyloid β Peptide Generation. 284:11863-11872. 2009
Caveolin-1 Expression Is Required for the Development of Pulmonary Emphysema through Activation of the ATM-p53-p21 Pathway. 284:5462-5466. 2009
Evolution of metal(loid) binding sites in transcriptional regulators. 283:25706-25714. 2008
L-selectin-mediated lymphocyte-cancer cell interactions under low fluid shear conditions. 283:15816-15824. 2008
Assembly of heterohexameric trypanosome hexokinases reveals that hexokinase 2 is a regulable enzyme. 283:14963-14970. 2008
The hominoid-specific oncogene TBC1D3 activates ras and modulates epidermal growth factor receptor signaling and trafficking. 283:13233-13242. 2008
Convergent evolution of a new arsenic binding site in the ArsR/SmtB family of metalloregulators. 282:34346-34355. 2007
ArsD residues Cys¹², Cys¹³, and Cys¹⁸ form an As(III)-binding site required for arsenic metallochaperone activity. 282:16783-16791. 2007
HCELL is the major E- and L-selectin ligand expressed on LS174T colon carcinoma cells. 281:13899-13905. 2006
Cys-113 and Cys-422 form a high affinity metalloid binding site in the ArsA ATPase. 281:9925-9934. 2006
Hypothyroid phenotype is contributed by mitochondrial complex I inactivation due to translocated neuronal nitric-oxide synthase. 281:4779-4786. 2006
Bacterial cell killing mediated by topoisomerase I DNA cleavage activity. 280:38489-38495. 2005
Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin - Implications for KD1 specificity of inhibition. 280:27832-27838. 2005
Inhibition of protein-tyrosine phosphatases by mild oxidative stresses is dependent on S-nitrosylation. 280:14453-14461. 2005
Nonequivalence of the nucleotide binding domains of the ArsA ATPase. 280:9921-9926. 2005
The tryptophan-rich motifs of the thrombospondin type 1 repeats bind VLAL motifs in the latent transforming growth factor-β complex. 279:47633-47642. 2004
Protein kinase C θ inhibits insulin signaling by phosphorylating IRS1 at Ser¹¹⁰¹. 279:45304-45307. 2004
Site-directed mutagenesis of residues involved in G strand DNA binding by Escherichia coli DNA topoisomerase I. 279:39207-39213. 2004
Leishmania major LmACR2 is a pentavalent antimony reductase that confers sensitivity to the drug Pentostam. 279:37445-37451. 2004
Molecular interactions that confer latency to transforming growth factor-β. 279:38032-38039. 2004
Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin. 279:31010-31017. 2004
As(III) and Sb(III) uptake by G1pF and efflux by ArsB in Escherichia coli. 279:18334-18341. 2004
Arsenic trioxide uptake by hexose permeases in Saccharomyces cerevisiae. 279:17312-17318. 2004
Structure-function analysis of the reactive site in the first Kunitz-type domain of human tissue factor pathway inhibitor-2. 279:17500-17507. 2004
5-aza-2′-deoxycytidine activates the p53/p21^Waf1/Cip1 pathway to inhibit cell proliferation. 279:15161-15166. 2004
Flexibility at Gly-194 is required for DNA cleavage and relaxation activity of Escherichia coli DNA topoisomerase I. 279:8648-8654. 2004
Direct interaction between Escherichia coli RNA polymerase and the zinc ribbon domains of DNA topoisomerase I. 278:30705-30710. 2003
Molecular cloning and characterization of spurt, a human novel gene that is retinoic acid-inducible and encodes a secretory protein specific in upper respiratory tracts. 278:1165-1173. 2003
Biochemical characterization of CopA, the Escherichia coli Cu(I)-translocating P-type ATPase. 277:46987-46992. 2002
1,25-dihydroxyvitamin D down-regulates cell membrane growth- and nuclear growth-promoting signals by the epidermal growth factor receptor. 277:38965-38971. 2002
Unisite and multisite catalysis in the ArsA ATPase. 277:23815-23820. 2002
Differential L-selectin binding activities of human hematopoietic cell L-selectin ligands, HCELL and PSGL-1. 276:47623-47631. 2001
The phosphatase C(X)₅R motif is required for catalytic activity of the Saccharomyces cerevisiae Acr2p arsenate reductase. 276:34738-34742. 2001
Conformational changes in four regions of the Escherichia coli ArsA ATPase link ATP hydrolysis to ion translocation. 276:30414-30422. 2001
Role of cysteinyl residues in sensing Pb(II), Cd(II), and Zn(II) by the plasmid pI258 CadC repressor. 276:14955-14960. 2001
A kinetic model for the action of a resistance efflux pump. 276:6378-6391. 2001
A novel membrane-anchored rab5 interacting protein required for homotypic endosome fusion. 275:24661-24669. 2000
Purification and characterization of Acr2p, the Saccharomyces cerevisiae arsenate reductase. 275:21149-21157. 2000
The acidic triad conserved in type IA DNA topoisomerases is required for binding of Mg(II) and subsequent conformational change. 275:5318-5322. 2000
The ATPase mechanism of ArsA, the catalytic subunit of the arsenite pump. 274:16153-16161. 1999
Binding of xanthine oxidase to vascular endothelium - Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling. 274:4985-4994. 1999
Pb(II)-translocating P-type ATPases. 273:32614-32617. 1998
A novel mechanism-based inhibitor (6′-bromo-5′,6′-didehydro-6′-deoxy-6′-fluorohomoadenosine) that covalently modifies human placental S-adenosylhomocysteine hydrolase. 273:18191-18197. 1998
CONSTRUCTION OF A CHIMERIC ARSA-ARSB PROTEIN FOR OVEREXPRESSION OF THE OXYANION-TRANSLOCATING ATPASE. 267:25768-25775. 1992
ZINC(II) COORDINATION IN ESCHERICHIA-COLI DNA TOPOISOMERASE-I IS REQUIRED FOR CLEAVABLE COMPLEX-FORMATION WITH DNA. 266:14317-14320. 1991
SUBSTRATE-INDUCED DIMERIZATION OF THE ARSA PROTEIN, THE CATALYTIC COMPONENT OF AN ANION-TRANSLOCATING ATPASE. 266:2327-2332. 1991
MUTAGENESIS OF A NUCLEOTIDE-BINDING SITE OF AN ANION-TRANSLOCATING ATPASE. 265:7832-7836. 1990
MOLECULAR CHARACTERIZATION OF AN ANION PUMP - THE ARSB PROTEIN IS THE MEMBRANE ANCHOR FOR THE ARSA PROTEIN. 265:190-194. 1990
CHARACTERIZATION OF THE CATALYTIC SUBUNIT OF AN ANION PUMP. 264:17349-17354. 1989
MAINTENANCE OF INTRACELLULAR CALCIUM IN ESCHERICHIA-COLI. 262:12570-12574. 1987
RECONSTITUTION OF ATP-DEPENDENT CALCIUM-TRANSPORT FROM STREPTOCOCCI. 261:5596-5600. 1986
NUCLEOTIDE-SEQUENCE OF THE STRUCTURAL GENES FOR AN ANION PUMP - THE PLASMID-ENCODED ARSENICAL RESISTANCE OPERON. 261:5030-5038. 1986
UNCOUPLING OF THE DNA BREAKING AND REJOINING STEPS OF ESCHERICHIA-COLI TYPE-I DNA TOPOISOMERASE - DEMONSTRATION OF AN ACTIVE COVALENT PROTEIN-DNA COMPLEX. 261:931-935. 1986
CATION PROTON ANTIPORT SYSTEMS IN ESCHERICHIA-COLI - SOLUBILIZATION AND RECONSTITUTION OF DELTA-PH-DRIVEN SODIUM PROTON AND CALCIUM PROTON ANTIPORTERS. 261:678-683. 1986
CALCIUM EFFLUX FROM ESCHERICHIA-COLI - EVIDENCE FOR 2 SYSTEMS. 259:6142-6146. 1984
PHYLOGENETIC CONSERVATION OF A CLASS-III MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGEN, FACTOR-B - ISOLATION AND NUCLEOTIDE SEQUENCING OF MOUSE FACTOR-B CDNA CLONES. 258:4693-4697. 1983
CATION-PROTON ANTIPORT SYSTEMS IN ESCHERICHIA-COLI - PROPERTIES OF THE POTASSIUM-PROTON ANTIPORTER. 255:39-44. 1980
COVALENT BONDS BETWEEN PROTEIN AND DNA - FORMATION OF PHOSPHOTYROSINE LINKAGE BETWEEN CERTAIN DNA TOPOISOMERASES AND DNA. 255:5560-5565. 1980
CATION-PROTON ANTIPORT SYSTEMS IN ESCHERICHIA-COLI - PROPERTIES OF THE CALCIUM-PROTON ANTIPORTER. 254:1957-1963. 1979
BASIC AMINO-ACID TRANSPORT IN ESCHERICHIA-COLI .2. PURIFICATION AND PROPERTIES OF AN ARGININE-SPECIFIC BINDING PROTEIN. 248:1211-1218. 1973
ApoC-III is a novel inducer of calcification in human aortic valves. 296.
CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions. 296.
Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells. 296.
Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly. 296.
"It's completely erasure": A Qualitative Exploration of Experiences of Transgender, Nonbinary, Gender Nonconforming, and Questioning Students in Biology Courses 2023
RNA synthesis by a translesion DNA polymerase mediates RNA base damage repair 2023
ESCHERICHIA-COLI DNA TOPOISOMERASE-I IS A ZINC METALLOPROTEIN WITH 3 REPETITIVE ZINC-BINDING DOMAINS 1988
MOLECULAR CHARACTERIZATION OF AN ANION PUMP - THE ARSA GENE-PRODUCT IS AN ARSENITE(ANTIMONATE)-STIMULATED ATPASE 1988
CATION-PROTON ANTIPORT SYSTEMS IN ESCHERICHIA-COLI - ABSENCE OF POTASSIUM-PROTON ANTIPORTER ACTIVITY IN A PH-SENSITIVE MUTANT 1980
Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 cells by tyrosine-containing peptides 2007
Mammalian zinc transport, trafficking, and signals 2006
Protamines, in the footsteps of linker histone evolution 2006
Escherichia coli soft metal ion-translocating ATPases 2000
A Novel High Throughput Screening (HTS) Method to Discover Bacterial DNA Gyrase Poisons 2025
In vitro synthesizing unmodified supercoiled circular DNA molecules 2025
RNA-seq Analysis of Serum Starvation in H. pylori 2025
Identification of flexible hinge region residues in bacterial topoisomerase IA 2024
Revealing the nucleic acid interactions of human topoisomerase 3 beta, a unique dualacting topoisomerase, and discovering its inhibitors 2024
Enrichment and Analysis of Head and Neck Cancer Mucin-Domain Glycoproteins Reveals the Presence of Tumor-Derived Immunoglobulin A 2023
PSI relieves the pressure of membrane fusion 2020
Nitroalkenes confer acute cardioprotection via adenine nucleotide translocase 1 (vol 287, pg 3573, 2012) 2015