Meira De Eirin-Lopez, Joseph

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Meira De Eirin-Lopez, Joseph Graduate Faculty

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Affiliated Member, Institute of Environment , College of Arts, Sciences & Education

jeirinlo@fiu.edu

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overview

Dr. Jose M. Eirin-Lopez is an associate professor in the Department of Biological Sciences at Florida International University (Miami, FL). He is also an affiliated faculty in the Center for Coastal Oceans Research at the Institute of Environment, as well as in the CREST Center for Aquatiic Chemistry and Environment at this institution. Since 2007, he is the principal investigator at the Environmental Epigenetics Lab. His research aims to make fundamental contributions to the study of marine environmental epigenetics using molecular, ecological and toxicological approaches.

selected scholarly works & creative activities

Article
- 2024
  
  Ecological forensic testing: Using multiple primers for eDNA detection of marine vertebrates in an estuarine lagoon subject to anthropogenic influences. Gene. 928.
  Full Text via DOI: 10.1016/j.gene.2024.148720 Web of Science: 001273501700001
- 2024
  
  Protamines and the sperm nuclear basic proteins Pandora's Box of insects. Biochemistry and Cell Biology.
  Full Text via DOI: 10.1139/bcb-2023-0363 Web of Science: 001208116400001
- 2024
  
  Multi-omic characterization of mechanisms contributing to rapid phenotypic plasticity in the coral Acropora cervicornis under divergent environments. Coral Reefs. 43:53-66.
  Full Text via DOI: 10.1007/s00338-023-02446-9 Web of Science: 001117689700001
- 2023
  
  Relationships between phenotypic plasticity and epigenetic variation in two Caribbean Acropora corals. Molecular Ecology. 32:4814-4828.
  Full Text via DOI: 10.1111/mec.17072 Web of Science: 001030837000001
- 2022
  
  Age group DNA methylation differences in lemon sharks (Negaprion brevirostris): Implications for future age estimation tools. Ecology and Evolution. 12.
  Full Text via DOI: 10.1002/ece3.9226 Web of Science: 000847288200001
- 2022
  
  Coral-bleaching responses to climate change across biological scales. Global Change Biology. 28:4229-4250.
  Full Text via DOI: 10.1111/gcb.16192 Web of Science: 000787738600001
- 2022
  
  Invertebrate methylomes provide insight into mechanisms of environmental tolerance and reveal methodological biases. Molecular Ecology Resources. 22:1247-1261.
  Full Text via DOI: 10.1111/1755-0998.13542 Web of Science: 000718383000001
- 2022
  
  Symbiont shuffling induces differential DNA methylation responses to thermal stress in the coral Montastraea cavernosa. Molecular Ecology. 31:588-602.
  Full Text via DOI: 10.1111/mec.16246 Web of Science: 000714863200001
- 2021
  
  Evolution of Methyltransferase-Like (METTL) Proteins in Metazoa: A Complex Gene Family Involved in Epitranscriptomic Regulation ana Other Epigenetic Processes. Molecular Biology and Evolution (MBE). 38:5309-5327.
  Full Text via DOI: 10.1093/molbev/msab267 Web of Science: 000741368600007
- 2021
  
  Evolution of a histone variant involved in compartmental regulation of NAD metabolism. Nature Structural & Molecular Biology. 28:1009-+.
  Full Text via DOI: 10.1038/s41594-021-00692-5 Web of Science: 000728721400013
- 2021
  
  Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas. Ecological Indicators. 127.
  Full Text via DOI: 10.1016/j.ecolind.2021.107793 Web of Science: 000658937700003
- 2021
  
  Application of an Improved Chloroform-Free Lipid Extraction Method to Staghorn Coral (Acropora cervicornis) Lipidomics Assessments. Bulletin of Environmental Contamination and Toxicology. 107:92-99.
  Full Text via DOI: 10.1007/s00128-020-03078-3 Web of Science: 000604487500008
- 2020
  
  Genome-Wide DNA Methylation Analysis Reveals a Conserved Epigenetic Response to Seasonal Environmental Variation in the Staghorn Coral Acropora cervicornis. Frontiers in Marine Science. 7.
  Full Text via DOI: 10.3389/fmars.2020.560424 Web of Science: 000582739600001
- 2019
  
  Protamines from liverwort are produced by post-translational cleavage and C-terminal di-aminopropanelation of several male germ-specific H1 histones. Journal of Biological Chemistry. 294:16364-16373.
  Full Text via DOI: 10.1074/jbc.RA119.010316 Web of Science: 000499478600039
- 2019
  
  The Bottlenose Dolphin Epigenetic Aging Tool (BEAT): A Molecular Age Estimation Tool for Small Cetaceans. Frontiers in Marine Science. 6.
  Full Text via DOI: 10.3389/fmars.2019.00561 Web of Science: 000488121900001
- 2019
  
  SEASONAL DNA METHYLATION VARIATION IN THE FLAT TREE OYSTER ISOGNOMON ALATUS FROM A MANGROVE ECOSYSTEM IN NORTH BISCAYNE BAY, FLORIDA. Journal of Shellfish Research. 38:79-88.
  Full Text via DOI: 10.2983/035.038.0108 Web of Science: 000464930800008
- 2018
  
  Coral epigenetic responses to nutrient stress: Histone H2A.X phosphorylation dynamics and DNA methylation in the staghorn coral Acropora cervicornis. Ecology and Evolution. 8:12193-12207.
  Full Text via DOI: 10.1002/ece3.4678 Web of Science: 000454107200070
- 2018
  
  Karyotype Characterization of Nine Periwinkle Species (Gastropoda, Littorinidae). Genes. 9.
  Full Text via DOI: 10.3390/genes9110517 Web of Science: 000451636700002
- 2017
  
  Detection of invasive and cryptic species in marine mussels (Bivalvia, Mytilidae): A chromosomal perspective. Journal for Nature Conservation. 39:58-67.
  Full Text via DOI: 10.1016/j.jnc.2017.07.005 Web of Science: 000410880400003
- 2017
  
  Molecular and Biochemical Methods Useful for the Epigenetic Characterization of Chromatin-Associated Proteins in Bivalve Molluscs. Frontiers in Physiology. 8.
  Full Text via DOI: 10.3389/fphys.2017.00490 Web of Science: 000407608200001
- 2017
  
  Transcriptional and biochemical analysis of antioxidant enzymes in the mussel Mytilus galloprovincialis during experimental exposures to the toxic dinoflagellate Prorocentrum lima. Marine Environmental Research. 129:304-315.
  Full Text via DOI: 10.1016/j.marenvres.2017.06.009 Web of Science: 000407981500027
- 2017
  
  Basic surface features of nuclear FKBPs facilitate chromatin binding. Scientific Reports. 7.
  Full Text via DOI: 10.1038/s41598-017-04194-7 Web of Science: 000403650300038
- 2017
  
  Effects of Florida Red Tides on histone variant expression and DNA methylation in the Eastern oyster Crassostrea virginica. Aquatic Toxicology. 186:196-204.
  Full Text via DOI: 10.1016/j.aquatox.2017.03.006 Web of Science: 000401386100020
- 2016
  
  Characterization of mussel H2AZ2: a new H2A.Z variant preferentially expressed in germinal tissues from Mytilus. Biochemistry and Cell Biology. 94:480-490.
  Full Text via DOI: 10.1139/bcb-2016-0056 Web of Science: 000386056700011
- 2016
  
  Unique yeast histone sequences influence octamer and nucleosome stability. FEBS Letters. 590:2629-2638.
  Full Text via DOI: 10.1002/1873-3468.12266 Web of Science: 000383600300014
- 2016
  
  Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis. Toxins. 8.
  Full Text via DOI: 10.3390/toxins8060159 Web of Science: 000378808700002
- 2016
  
  The characterization of macroH2A beyond vertebrates supports an ancestral origin and conserved role for histone variants in chromatin. Epigenetics. 11:415-425.
  Full Text via DOI: 10.1080/15592294.2016.1172161 Web of Science: 000380902700003
- 2015
  
  Unbiased high-throughput characterization of mussel transcriptomic responses to sublethal concentrations of the biotoxin okadaic acid. PeerJ. 3.
  Full Text via DOI: 10.7717/peerj.1429 Web of Science: 000365803400013
- 2015
  
  An Unusual Role for doublesex in Sex Determination in the Dipteran Sciara. Genetics. 200:1181-+.
  Full Text via DOI: 10.1534/genetics.115.177972 Web of Science: 000359917000017
- 2015
  
  IN VITRO ANALYSIS OF EARLY GENOTOXIC AND CYTOTOXIC EFFECTS OF OKADAIC ACID IN DIFFERENT CELL TYPES OF THE MUSSEL Mytilus galloprovincialis. Journal of Toxicology and Environmental Health - Part A. 78:814-824.
  Full Text via DOI: 10.1080/15287394.2015.1051173 Web of Science: 000357938400004
- 2015
  
  Evolution of High Mobility Group Nucleosome-Binding Proteins and Its Implications for Vertebrate Chromatin Specialization. Molecular Biology and Evolution (MBE). 32:121-131.
  Full Text via DOI: 10.1093/molbev/msu280 Web of Science: 000350050200011
- 2015
  
  The comparative study of five sex-determining proteins across insects unveils high rates of evolution at basal components of the sex determination cascade. Development Genes and Evolution. 225:23-30.
  Full Text via DOI: 10.1007/s00427-015-0491-6 Web of Science: 000349029300003
- 2013
  
  The CHROMEVALOA Database: A Resource for the Evaluation of Okadaic Acid Contamination in the Marine Environment Based on the Chromatin-Associated Transcriptome of the Mussel Mytilus galloprovincialis. Marine Drugs. 11:830-841.
  Full Text via DOI: 10.3390/md11030830 Web of Science: 000316607800016
- 2013
  
  The evolution of sex-related traits and genes 2012.. International Journal of Evolutionary Biology. 2013:590769.
  Full Text via DOI: 10.1155/2013/590769
- 2012
  
  Histone H2A (H2A.X and H2A.Z) Variants in Molluscs: Molecular Characterization and Potential Implications For Chromatin Dynamics. PLoS ONE. 7.
  Full Text via DOI: 10.1371/journal.pone.0030006 Web of Science: 000301355700074
- 2012
  
  The Birth-and-Death Evolution of Multigene Families Revisited. Genome Dynamics. 7:170-196.
  Web of Science: 000310249100011
- 2011
  
  Protamines: Structural Complexity, Evolution and Chromatin Patterning. Protein and Peptide Letters. 18:755-771.
  Web of Science: 000293852700002
- 2010
  
  Birth-and-Death Long-Term Evolution Promotes Histone H2B Variant Diversification in the Male Germinal Cell Line. Molecular Biology and Evolution (MBE). 27:1802-1812.
  Full Text via DOI: 10.1093/molbev/msq058 Web of Science: 000280296700008
- 2010
  
  The gene transformer-2 of Anastrepha fruit flies (Diptera, Tephritidae) and its evolution in insects. BMC Evolutionary Biology. 10.
  Full Text via DOI: 10.1186/1471-2148-10-140 Web of Science: 000279827800001
- 2010
  
  Evolutionary Dynamics of the 5S rDNA Gene Family in the Mussel Mytilus: Mixed Effects of Birth-and-Death and Concerted Evolution. Journal of Molecular Evolution. 70:413-426.
  Full Text via DOI: 10.1007/s00239-010-9341-3 Web of Science: 000278094800002
- 2010
  
  H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesis. Nucleic Acids Research (NAR). 38:1780-1789.
  Full Text via DOI: 10.1093/nar/gkp1129 Web of Science: 000276304600011
- 2009
  
  Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates. BMC Biology. 7.
  Full Text via DOI: 10.1186/1741-7007-7-86 Web of Science: 000273536900001
- 2009
  
  Histone genes of the razor clam Solen marginatus unveil new aspects of linker histone evolution in protostomes. Genome. 52:597-607.
  Full Text via DOI: 10.1139/G09-034 Web of Science: 000268853700002
- 2009
  
  The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues. BMC Evolutionary Biology. 9.
  Full Text via DOI: 10.1186/1471-2148-9-31 Web of Science: 000264074500002
- 2008
  
  The sperm proteins from amphioxus mirror its basal position among chordates and redefine the origin of vertebrate protamines. Molecular Biology and Evolution (MBE). 25:1705-1713.
  Full Text via DOI: 10.1093/molbev/msn121 Web of Science: 000257789200022
- 2008
  
  Early evolution of histone genes: Prevalence of an 'Orphon' H1 lineage in protostomes and birth-and-death process in the H2A family. Journal of Molecular Evolution. 66:505-518.
  Full Text via DOI: 10.1007/s00239-008-9109-1 Web of Science: 000256090200009
- 2008
  
  H2A.Bbd:: a quickly evolving hypervariable mammalian histone that destabilizes nucleosomes in an acetylation-independent way. The FASEB Journal. 22:316-326.
  Full Text via DOI: 10.1096/fj.07-9255com Web of Science: 000252309900033
- 2008
  
  Insight into ligand diversity and novel biological roles for family 32 carbohydrate-binding modules. Molecular Biology and Evolution (MBE). 25:155-167.
  Full Text via DOI: 10.1093/molbev/msm243 Web of Science: 000253375900016
- 2007
  
  The Gene Transformer of Anastrepha Fruit Flies (Diptera, Tephritidae) and Its Evolution in Insects. PLoS ONE. 2.
  Full Text via DOI: 10.1371/journal.pone.0001239 Web of Science: 000207459300020
- 2007
  
  The gene doublesex of Anastrepha fruit flies (Diptera, Tephritidae) and its evolution in insects. Development Genes and Evolution. 217:725-731.
  Full Text via DOI: 10.1007/s00427-007-0178-8 Web of Science: 000249968700006
- 2007
  
  H2A.Z-mediated genome-wide chromatin specialization. Current Genomics. 8:59-66.
  Full Text via DOI: 10.2174/138920207780076965 Web of Science: 000244925700006
- 2006
  
  A unique vertebrate histone H1-related protamine-like protein results in an unusual sperm chromatin organization. The FEBS Journal. 273:4548-4561.
  Full Text via DOI: 10.1111/j.1742-4658.2006.05461.x Web of Science: 000240558500018
- 2006
  
  Long-term evolution and functional diversification in the members of the nucleophosmin/nucleoplasmin family of nuclear chaperones. Genetics. 173:1835-1850.
  Full Text via DOI: 10.1534/genetics.106.058990 Web of Science: 000240620100002
- 2006
  
  Common phylogenetic origin of protamine-like (PL) proteins and histone H1:: Evidence from bivalve PL genes. Molecular Biology and Evolution (MBE). 23:1304-1317.
  Full Text via DOI: 10.1093/molbev/msk021 Web of Science: 000237696800022
- 2006
  
  The characterization of amphibian nucleoplasmins yields new insight into their role in sperm chromatin remodeling. BMC Genomics. 7.
  Full Text via DOI: 10.1186/1471-2164-7-99 Web of Science: 000238291600001
- 2006
  
  Sperm nuclear basic proteins of two closely related species of Scorpaeniform fish (Sebastes maliger, Sebastolobus sp.) with different sexual reproduction and the evolution of fish protamines. Journal of Experimental Zoology Part A: Ecological and Integrative Physiology. 305A:277-287.
  Full Text via DOI: 10.1002/jez.a.239 Web of Science: 000236010700009
- 2005
  
  Common evolutionarv orign and birth-and-death process in the replication-independent histone H1 isoforms from vertebrate and invertebrate genomes. Journal of Molecular Evolution. 61:398-407.
  Full Text via DOI: 10.1007/s00239-004-0328-9 Web of Science: 000231732400013
- 2005
  
  H2AX: tailoring histone H2A for chromatin-dependent genomic integrity. Biochemistry and Cell Biology. 83:505-515.
  Full Text via DOI: 10.1139/O05-114 Web of Science: 000231466300011
- 2004
  
  Birth-and-death evolution with strong purifying selection in the histone H1 multigene family and the origin of orphon H1 genes. Molecular Biology and Evolution (MBE). 21:1992-2003.
  Full Text via DOI: 10.1093/molbev/msh213 Web of Science: 000224013100017
- 2004
  
  The gene Sex-lethal of the Sciaridae family (order Diptera, suborder Nematocera) and its phylogeny in dipteran insects. Genetics. 168:907-921.
  Full Text via DOI: 10.1534/genetics.104.031278 Web of Science: 000225063100029
- 2004
  
  Molecular evolutionary characterization of the mussel Mytilus histone multigene family:: First record of a tandemly repeated unit of five histone genes containing an H1 subtype with "orphon" features. Journal of Molecular Evolution. 58:131-144.
  Full Text via DOI: 10.1007/s00239-003-2531-5 Web of Science: 000188769200001
- 2002
  
  Molecular and evolutionary analysis of mussel histone genes (Mytilus spp.):: Possible evidence of an "orphon origin" for H1 histone genes. Journal of Molecular Evolution. 55:272-283.
  Full Text via DOI: 10.1007/s00239-002-2325-1 Web of Science: 000177512700004
- A computer lab exploring evolutionary aspects of chromatin structure and dynamics for an undergraduate chromatin course*. Biochemistry and Molecular Biology Education. 41:95-102.
  Full Text via DOI: 10.1002/bmb.20667 Web of Science: 000316694400006
Book Chapter
- 2018
  
  Environmental Epigenomics and Its Applications in Marine Organisms. 325-359.
  Full Text via DOI: 10.1007/13836_2018_28
- 2015
  
  Computational Methods in Epigenetics. 153-180.
  Full Text via DOI: 10.1016/B978-0-12-420135-4.00006-1
- 2015
  
  Chapter 6 Computational Methods in Epigenetics. 153-180.
  Full Text via DOI: 10.1016/b978-0-12-420135-4.00006-1
Conference
- 2017
  
  Characterization of epigenetic marks in marine invertebrates. Biochemistry and Cell Biology. 181-181.
  Web of Science: 000399165600012
- 2017
  
  First in vivo characterization of macroH2A beyond vertebrates: new insights into the functional evolution of histone variants. Biochemistry and Cell Biology. 180-180.
  Web of Science: 000399165600010
- 2017
  
  Framing epigenetic signatures of the Pacific oyster under environmental stress using network analysis. Biochemistry and Cell Biology. 184-184.
  Web of Science: 000399165600025
- 2017
  
  TRANSCRIPTOME PROFILING AND DIFFERENTIAL GENE EXPRESSION IN MUSSELS EXPOSED TO Prorocentrum lima, A DINOFLAGELLATE PRODUCING DSP TOXINS. Aquaculture. 152-153.
  Web of Science: 000411454500202
- 2013
  
  Characterization of histone variants in bivalve molluscs and their relevance in the development of chromatin-based tests for evaluating ocadaic acid genotoxicity in the marine environment. Biochemistry and Cell Biology. 395-395.
  Web of Science: 000327142700005
- 2013
  
  Clustering of Gene Expression Profiles Applied to Marine Research. Lecture Notes in Computer Science. 453-+.
  Web of Science: 000324897700045
- 2009
  
  Long-Term Evolution of Histone Families: Old Notions and New Insights into Their Mechanisms of Diversification Across Eukaryotes. 139-+.
  Full Text via DOI: 10.1007/978-3-642-00952-5_8 Web of Science: 000270816600008
- 2007
  
  Evolution and revolutions of nuclear chaperones in chromatin remodeling: the nucleophosmin-nucleoplasmin family. Biochemistry and Cell Biology. 527-527.
  Web of Science: 000249428900025
- 2006
  
  Histone H1 function and distribution in chromatin: what does molecular evolution tell us about it?. Biochemistry and Cell Biology. 658-658.
  Full Text via DOI: 10.1139/006-901 Web of Science: 000240053100024
Editorial Material
- 2022
  
  Editorial: Adaptation and Phenotypic Plasticity to Climate Change. Frontiers in Marine Science.
  Full Text via DOI: 10.3389/fmars.2022.893117
Other Scholarly Work
- 2021
  
  Editorial: Marine Environmental Epigenetics. Frontiers in Marine Science.
  Full Text via DOI: 10.3389/fmars.2021.685075 Web of Science: 000656143100001
- 2011
  
  Boule and the Evolutionary Origin of Metazoan Gametogenesis: A Grandpa's Tale.. International Journal of Evolutionary Biology. 972457.
  Full Text via DOI: 10.4061/2011/972457
- 2011
  
  The evolution of sex-related traits and genes.. International Journal of Evolutionary Biology. 807218.
  Full Text via DOI: 10.4061/2011/807218
Preprint
Review
- 2021
  
  Coral environmental memory: causes, mechanisms, and consequences for future reefs. Trends in Ecology and Evolution. 1011-1023.
  Full Text via DOI: 10.1016/j.tree.2021.06.014 Web of Science: 000709722700011
- 2020
  
  Deciphering the Enigma of the Histone H2A.Z-1/H2A.Z-2 Isoforms: Novel Insights and Remaining Questions. Cells.
  Full Text via DOI: 10.3390/cells9051167 Web of Science: 000539340200101
- 2019
  
  Marine Environmental Epigenetics. Annual Review of Marine Science. 335-+.
  Full Text via DOI: 10.1146/annurev-marine-010318-095114 Web of Science: 000456386600015
- 2015
  
  Environmental epigenetics: A promising venue for developing next-generation pollution biomonitoring tools in marine invertebrates. Marine Pollution Bulletin. 5-13.
  Full Text via DOI: 10.1016/j.marpolbul.2015.06.020 Web of Science: 000362134100014
- 2013
  
  Bivalve Omics: State of the Art and Potential Applications for the Biomonitoring of Harmful Marine Compounds. Marine Drugs. 4370-4389.
  Full Text via DOI: 10.3390/md11114370 Web of Science: 000330521400015
- 2013
  
  Okadaic Acid Meet and Greet: An Insight into Detection Methods, Response Strategies and Genotoxic Effects in Marine Invertebrates. Marine Drugs. 2829-2845.
  Full Text via DOI: 10.3390/md11082829 Web of Science: 000330521300010
- 2012
  
  Vertebrate nucleoplasmin and NASP: egg histone storage proteins with multiple chaperone activities. The FASEB Journal. 4788-4804.
  Full Text via DOI: 10.1096/fj.12-216663 Web of Science: 000311838300003
- 2012
  
  A unified phylogeny-based nomenclature for histone variants. Epigenetics and Chromatin.
  Full Text via DOI: 10.1186/1756-8935-5-7 Web of Science: 000305622000001
- 2012
  
  Chromatin specialization in bivalve molluscs: A leap forward for the evaluation of Okadaic Acid genotoxicity in the marine environment. Comparative Biochemistry and Physiology, Part C. 175-181.
  Full Text via DOI: 10.1016/j.cbpc.2011.09.003 Web of Science: 000299580200001
- 2009
  
  Origin and evolution of chromosomal sperm proteins. BioEssays. 1062-1070.
  Full Text via DOI: 10.1002/bies.200900050 Web of Science: 000270769400007
- 2008
  
  Quickly evolving histones, nucleosome stability and chromatin folding:: All about histone H2A.Bbd. Gene. 1-7.
  Full Text via DOI: 10.1016/j.gene.2008.02.003 Web of Science: 000255625000001
- 2007
  
  Evolution of vertebrate chromosomal sperm proteins: implications for fertility and sperm competition.. 63-79.
- 2007
  
  New insights into the nucleophosmin/nucleoplasmin family of nuclear chaperones. BioEssays. 49-59.
  Full Text via DOI: 10.1002/bies.20512 Web of Science: 000243336700007
- 2006
  
  Protamines, in the footsteps of linker histone evolution. Journal of Biological Chemistry. 1-4.
  Full Text via DOI: 10.1074/jbc.R500018200 Web of Science: 000234307200001

principal investigator on

co-principal investigator on

Grant
- CREST Phase II: Center for Aquatic Chemistry and Environment (CREST-CAChE) awarded by National Science Foundation 2021 - 2027

subproject principal investigator on

Women's Explorer Award awarded by Herbert Gruber 2022 - 2027

full name

Joseph Meira De Eirin-Lopez

visualizations

Co-author Network

Co-investigator Network