FIU Discovery

Targeted metabolomics reveals plasma biomarkers and metabolic alterations of the aging process in healthy young and older adults.  GeroScience.  45:3131-3146.

Identifying biodegradation pathways of cetrimonium bromide (CTAB) using metagenome, metatranscriptome, and metabolome tri-omics integration.  Water Research.  246.

Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice.  Journal of Neuroinflammation.  20.

Maternal PBDE exposure disrupts gut microbiome and promotes hepatic proinflammatory signaling in humanized PXR-transgenic mouse offspring over time.  Toxicological Sciences.  194:209-225.

Increased cardiac PFK-2 protects against high-fat diet-induced cardiomyopathy and mediates beneficial systemic metabolic effects.  iScience.  26.

Ceramide compensation by ceramide synthases preserves retinal function and structure in a retinal dystrophy mouse model.  DMM Disease Models and Mechanisms.  16.

Multi-omic assessment shows dysregulation of pulmonary and systemic immunity to e-cigarette exposure.  Respiratory Research.  24.

Metabolomic Profiling in Mouse Model of Menopause-Associated Asthma.  Metabolites.  13.

Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration.  Nature Metabolism.  5.

An integrative cellular metabolomic study reveals downregulated tricarboxylic acid cycle and potential biomarkers induced by tetrabromobisphenol A in human lung A549 cells.  Environmental Toxicology.  38:7-16.

Metabolomic Signatures of Autism Spectrum Disorder.  Journal of Personalized Medicine.  12.

Metabolites Associated With Fatigue and Physical Activity in Childhood Cancer.  Biological Research for Nursing.  24:350-361.

Central Nervous System Metabolism in Autism, Epilepsy and Developmental Delays: A Cerebrospinal Fluid Analysis.  Metabolites.  12.

Metabolomics of oxidative stress: Nrf2 independent depletion of NAD or increases of sugar alcohols.  Toxicology and Applied Pharmacology.  442.

The Role of NEDD4-1 in Tumorigenesis of the Digestive System.  Chinese Journal of Biochemistry and Molecular Biology.  38:410-417.

Hydrodefluorination of Perfluorooctanoic Acid in the H₂-Based Membrane Catalyst-Film Reactor with Platinum Group Metal Nanoparticles: Pathways and Optimal Conditions.  Environmental Science and Technology.  55:16699-16707.

Bile Acid Regulates the Colonization and Dissemination of Candida albicans from the Gastrointestinal Tract by Controlling Host Defense System and Microbiota.  Journal of Fungi.  7.

Metabolic Profile in Neonatal Pig Hearts.  Frontiers in Cardiovascular Medicine.  8.

Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK.  Molecular Cell.  81:3803-+.

Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance.  Biomaterials.  262.

Comprehensive Isotopic Targeted Mass Spectrometry: Reliable Metabolic Flux Analysis with Broad Coverage.  Analytical Chemistry.  92:11728-11738.

Insights into the Vastly Different Effects of Eutectic Solvents on the Stability of Phenolic Compounds.  Journal of Physical Chemistry Letters.  11:5268-5272.

In situ situ formation of thymol-based hydrophobic deep eutectic solvents: Application to antibiotics analysis in surface water based on liquid-liquid microextraction followed by liquid chromatography.  Journal of Chromatography A.  1614.

Systematic investigation of the extractive desulfurization of fuel using deep eutectic solvents from multifarious aspects.  Fuel.  264.

Mixing of menthol-based hydrophobic deep eutectic solvents as a novel method to tune their properties.  Journal of Molecular Liquids.  301.

Headspace conditions and ingredients can affect artefactual benzene formation in beverages.  Food Chemistry.  293:278-284.

An HPLC-UV-based quantitative analytical method for Chrysanthemum morifolium: development, validation, and application.  Analytical Science and Technology.  32:139-146.

Application of Deep Eutectic Solvents to Prepare Mixture Extracts of Three Long-Lived Trees with Maximized Skin-Related Bioactivities.  Applied Sciences (Switzerland).  9.

Establishment and validation of an analytical method for quality control of health functional foods derived from Agastache rugosa.  Analytical Science and Technology.  32:96-104.

A comprehensive metabolomics investigation of hippocampus, serum, and feces affected by chronic fluoxetine treatment using the chronic unpredictable mild stress mouse model of depression.  Scientific Reports.  9.

Comprehensive Investigation of the Effects of Brewing Conditions in Sample Preparation of Green Tea Infusions.  Molecules.  24.

Deep eutectic solvent-based valorization of spent coffee grounds.  Food Chemistry.  255:357-364.

One-step sample preparation for convenient examination of volatile monoterpenes and phenolic compounds in peppermint leaves using deep eutectic solvents.  Food Chemistry.  251:69-76.

Identification of Major Flavone C-Glycosides and Their Optimized Extraction from Cymbidium kanran Using Deep Eutectic Solvents.  Molecules.  22.

Simple and rapid determination of zaltoprofen in human plasma by manual-shaking-assisted dispersive liquid-liquid microextraction followed by liquid chromatography with ultraviolet detection.  Journal of Separation Science.  40:4050-4059.

Multi-functioning deep eutectic solvents as extraction and storage media for bioactive natural products that are readily applicable to cosmetic products.  Journal of Cleaner Production.  151:87-95.

A simple and reliable analytical method based on HPLC-UV to determine oleanonic acid content in Chios gum mastic for quality control.  Archives of Pharmacal Research.  40:49-56.

Determination of enantiomeric vigabatrin by derivatization with diacetyl-L-tartaric anhydride followed by ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry.  Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences.  1040:199-207.

Ultrasound-assisted chiral derivatization of etodolac with (1R)-(-)-menthyl chloroformate for the determination of etodolac enantiomers.  Arabian Journal of Chemistry.  9:S1962-S1972.

Cornuside inhibits mast cell-mediated allergic response by downregulating MAPK and NF-κB signaling pathways.  Biochemical and Biophysical Research Communications.  473:408-414.

Indirect enantioseparation of fluoxetine in mouse serum by derivatization with 1R-(-)-menthyl chloroformate followed by ultra high performance liquid chromatography and quadrupole time-of-flight mass spectrometry.  Journal of Separation Science.  39:1041-1049.

Cornuside ameliorates airway inflammation via Toll-like receptor 4 and Notch1 in asthmatic mice induced by lipopolysaccharide and ovalbumin.  International Journal of Clinical and Experimental Medicine.  9:15274-15284.

Hydroxysafflor yellow A attenuates allergic airway inflammation by suppressing the activity of nuclear factor-kappa B in ovalbumin-induced asthmatic mice.  International Journal of Clinical and Experimental Medicine.  9:21595-21604.

Tailoring and recycling of deep eutectic solvents as sustainable and efficient extraction media.  Journal of Chromatography A.  1424:10-17.

Highly efficient extraction of anthocyanins from grape skin using deep eutectic solvents as green and tunable media.  Archives of Pharmacal Research.  38:2143-2152.

Development and Validation of an Analytical Method Readily Applicable for Quality Control of Tabebuia impetiginosa (Taheebo) Ethanolic Extract.  Journal of AOAC International.  101:695-700.

Targeted Metabolomics Reveals Plasma Biomarkers and Metabolic Alterations of the Aging Process in Healthy Young and Older Adults.  The FASEB Journal.

Increased Cardiac PFK-2 Activity Protects Against High-Fat Diet-Induced Cardiomyopathy and Mediates Beneficial Systemic Metabolic Effects

Bile Acid Regulates the Colonization and Dissemination of Candida albicans from the Gastrointestinal Tract by Controlling Host Defense System and Microbiota

Scarless Enriched selection of Genome edited Human Pluripotent Stem Cells Using Induced Drug Resistance

Recent review on selected xenobiotics and their impacts on gut microbiome and metabolome.  TrAC. Trends in analytical chemistry.