Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing, in vivo, and enhanced deconvolution by computational methods Article

Houghten, Richard A, Pinilla, Clernencia, Giulianotti, Marc A et al. Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing, in vivo, and enhanced deconvolution by computational methods . 10(1), 3-19. 10.1021/cc7001205

cited authors

  • Houghten, Richard A; Pinilla, Clernencia; Giulianotti, Marc A; Appel, Jon R; Dooley, Colette T; Nefzi, Adel; Ostresh, John M; Yu, Yongping; Maggiora, Gerald M; Medina-Franco, Jose L; Brunner, Daniela; Schneider, Jeff

sustainable development goals

keywords

  • ACTIVE COMPOUNDS
  • CHEMICAL LIBRARIES
  • Chemistry
  • Chemistry, Applied
  • Chemistry, Medicinal
  • Chemistry, Multidisciplinary
  • DRUG DISCOVERY
  • ENERGY-TRANSFER PEPTIDES
  • INDINAVIR ANALOGS
  • KAPPA-OPIOID RECEPTORS
  • Life Sciences & Biomedicine
  • PHASE SYNTHESIS
  • POSITIONAL SCANNING LIBRARY
  • Pharmacology & Pharmacy
  • Physical Sciences
  • SMALL-MOLECULE ANTAGONISTS
  • SUBSTRATE-SPECIFICITY
  • Science & Technology

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 3

end page

  • 19

volume

  • 10

issue

  • 1