Liu, Yuan Graduate Faculty
- Associate Professor, Chemistry and Biochemistry , College of Arts, Sciences & Education
Overview
overview
- Yuan Liu, MD, PhD, joined the Department of Chemistry and Biochemistry at Florida International University in 2010 as a faculty member. Her research interests focus on understanding the molecular mechanisms by which DNA damage and repair modulates genome and epigenome stability and their roles in development, prevention, and treatment of human cancer and neurodegenerative diseases such as Huntingtonâs disease and Friedreichâs ataxia, among others. Additionally, Dr. Liu is exploring DNA repair as a biomarker for diagnosis, treatment and prognosis of cancer and human neurodegeneration, and drug discoveries of DNA repair inhibitors as treatments of human diseases.
Publications
Patents issued
selected scholarly works & creative activities
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Article
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2026Targeting Florida red tide: Curcumin inhibits Karenia brevis thioredoxin reductase. Plant Physiology and Biochemistry. 230.Full Text via DOI: 10.1016/j.plaphy.2025.110905 Web of Science: 001640508300001
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2025Unscheduled m6A Deposition in RNA via m6ATP Incorporation by DNA Polymerases. International Journal of Molecular Sciences. 26.Full Text via DOI: 10.3390/ijms26199263 Web of Science: 001594839400001
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2025Synthesis of Adenine Nucleosides with a Reactive (β-Iodovinyl)sulfone or (β-Keto)sulfone Group at the C2 Position and Their Polymerase-Catalyzed Incorporation into DNA. Molecules. 30.Full Text via DOI: 10.3390/molecules30061358 Web of Science: 001452720900001
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2025RNA damage and its implications in genome stability. DNA Repair. 147.Full Text via DOI: 10.1016/j.dnarep.2025.103821 Web of Science: 001440673500001
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2024Obesity increases genomic instability at DNA repeat-mediated endogenous mutation hotspots. Nature Communications. 15.Full Text via DOI: 10.1038/s41467-024-50006-8 Web of Science: 001275549300013
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2024DNA Base Damage Repair Crosstalks with Chromatin Structures to Contract Expanded GAA Repeats in Friedreich's Ataxia. Biomolecules. 14.Full Text via DOI: 10.3390/biom14070809 Web of Science: 001276522900001
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2023Brevetoxin induces a shift in the redox state of the proteome and unfolded protein response in human lymphoblast cells that can be alleviated with the acrolein scavenger MESNA. Environmental Toxicology and Pharmacology. 100.Full Text via DOI: 10.1016/j.etap.2023.104137 Web of Science: 000997780000001
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2023RNA-guided DNA base damage repair via DNA polymerase-mediated nick translation. Nucleic Acids Research (NAR). 51:166-181.Full Text via DOI: 10.1093/nar/gkac1178 Web of Science: 000899689000001
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2023Flap Endonuclease 1 Endonucleolytically Processes RNA to Resolve R-Loops through DNA Base Excision Repair. Genes. 14.Full Text via DOI: 10.3390/genes14010098 Web of Science: 000917568400001
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2022Purine Nucleosides with a Reactive (β-lodovinyl)sulfone or a (β-Keto)sulfone Group at the C8 Position and Their Polymerase-Catalyzed Incorporation into DNA. Asian Journal of Organic Chemistry. 11.Full Text via DOI: 10.1002/ajoc.202100764 Web of Science: 000752888700001
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2022Incorporation of 5',8-cyclo-2'deoxyadenosines by DNA repair polymerases via base excision repair. DNA Repair. 109.Full Text via DOI: 10.1016/j.dnarep.2021.103258 Web of Science: 000789227700003
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2021Scanning Ion Conductance Microscopy Study Reveals the Disruption of the Integrity of the Human Cell Membrane Structure by Oxidative DNA Damage. ACS Applied Bio Materials. 4:1632-1639.Full Text via DOI: 10.1021/acsabm.0c01461 Web of Science: 000620346200049
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2020R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities. Journal of Biological Chemistry. 295:13902-13913.Full Text via DOI: 10.1074/jbc.RA120.014161 Web of Science: 000578444100016
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2020Dynamic single-cell intracellular pH sensing using a SERS-active nanopipette. The Analyst. 145:4852-4859.Full Text via DOI: 10.1039/d0an00838a Web of Science: 000548664800012
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2020N6-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation. Environmental Pollution. 259.Full Text via DOI: 10.1016/j.envpol.2019.113908 Web of Science: 000528534600030
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2020Androgen Receptor and Poly(ADP-ribose) Glycohydrolase Inhibition Increases Efficiency of Androgen Ablation in Prostate Cancer Cells. Scientific Reports. 10.Full Text via DOI: 10.1038/s41598-020-60849-y Web of Science: 000562886900005
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2020Inhibition of base excision repair by natamycin suppresses prostate cancer cell proliferation. Biochimie. 168:241-250.Full Text via DOI: 10.1016/j.biochi.2019.11.008 Web of Science: 000503444300022
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2020Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a de novo DNA Methyltransferase. Cells. 9.Full Text via DOI: 10.3390/cells9010225 Web of Science: 000515398200225
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2019Tyrosyl-DNA Phosphodiesterase 1 and Topoisomerase I Activities as Predictive Indicators for Glioblastoma Susceptibility to Genotoxic Agents. Cancers. 11.Full Text via DOI: 10.3390/cancers11101416 Web of Science: 000498826000013
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2019Fluorescent 5-Pyrimidine and 8-Purine Nucleosides Modified with an N-Unsubstituted 1,2,3-Triazol-4-yl Moiety. Journal of Organic Chemistry. 84:3624-3631.Full Text via DOI: 10.1021/acs.joc.8b03135 Web of Science: 000461844000051
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2019Diastereomeric Recognition of 5′,8-cyclo-2′-Deoxyadenosine Lesions by Human Poly(ADP-ribose) Polymerase 1 in a Biomimetic Model. Cells. 8.Full Text via DOI: 10.3390/cells8020116 Web of Science: 000460896000038
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2019Methods to Study Trinucleotide Repeat Instability Induced by DNA Damage and Repair. Methods in molecular biology (Clifton, N.J.). 1999:87-101.Full Text via DOI: 10.1007/978-1-4939-9500-4_5 Web of Science: 000486994800006
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2018Electron-Mediated Aminyl and Iminyl Radicals from C5 Azido-Modified Pyrimidine Nucleosides Augment Radiation Damage to Cancer Cells. Organic Letters. 20:7400-7404.Full Text via DOI: 10.1021/acs.orglett.8b03035 Web of Science: 000452930100012
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2018The deoxyribose phosphate lyase of DNA polymerase β suppresses a processive DNA synthesis to prevent trinucleotide repeat instability. Nucleic Acids Research (NAR). 46:8940-8952.Full Text via DOI: 10.1093/nar/gky700 Web of Science: 000450952000029
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2018Pyrimidine Nucleosides with a Reactive (ß-Chlorovinyl)sulfone or (ß-Keto)sulfone Group at the C5 Position, Their Reactions with Nucleophiles and Electrophiles, and Their Polymerase-Catalyzed Incorporation into DNA. ACS Omega. 3:4276-4288.Full Text via DOI: 10.1021/acsomega.8b00584 Web of Science: 000430200300070
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2018An oxidized abasic lesion inhibits base excision repair leading to DNA strand breaks in a trinucleotide repeat tract. PLoS ONE. 13.Full Text via DOI: 10.1371/journal.pone.0192148 Web of Science: 000423793400072
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2017miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells. Scientific Reports. 7.Full Text via DOI: 10.1038/s41598-017-06061-x Web of Science: 000411434900021
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2017Brevetoxin-2, is a unique inhibitor of the C-terminal redox center of mammalian thioredoxin reductase-1. Toxicology and Applied Pharmacology. 329:58-66.Full Text via DOI: 10.1016/j.taap.2017.05.027 Web of Science: 000406735700007
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2017Protection of Nrf2 Against Arsenite-induced Oxidative Damage is Regulated by the Cyclic Guanosine Monophosphate-Protein Kinase G Signaling Pathway. Environmental Toxicology. 32:2004-2020.Full Text via DOI: 10.1002/tox.22374 Web of Science: 000405635000003
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2017Modulation of trinucleotide repeat instability by DNA polymerase beta polymorphic variant R137Q. PLoS ONE. 12.Full Text via DOI: 10.1371/journal.pone.0177299 Web of Science: 000400649500060
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2017Precision Sports Medicine: The Future of Advancing Health and Performance in Youth and Beyond. Strength and Conditioning Journal. 39:48-58.Web of Science: 000400010400007
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2016Proliferating cell nuclear antigen prevents trinucleotide repeat expansions by promoting repeat deletion and hairpin removal. DNA Repair. 48:17-29.Full Text via DOI: 10.1016/j.dnarep.2016.10.006 Web of Science: 000389091400003
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2016Crosstalk between MSH2-MSH3 and pol β promotes trinucleotide repeat expansion during base excision repair. Nature Communications. 7.Full Text via DOI: 10.1038/ncomms12465 Web of Science: 000381904700001
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2016AP endonuclease 1 prevents the extension of a T/G mismatch by DNA polymerase β to prevent mutations in CpGs during base excision repair. DNA Repair. 43:89-97.Full Text via DOI: 10.1016/j.dnarep.2016.03.006 Web of Science: 000379094500011
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2015Bypass of a 5′,8-cyclopurine-2′-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks. DNA Repair. 33:24-34.Full Text via DOI: 10.1016/j.dnarep.2015.06.004 Web of Science: 000359885100003
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2015AP endonuclease 1 prevents trinucleotide repeat expansion via a novel mechanism during base excision repair. Nucleic Acids Research (NAR). 43:5948-5960.Full Text via DOI: 10.1093/nar/gkv530 Web of Science: 000359775200028
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2015Resveratrol Protects Against Arsenic Trioxide-Induced Oxidative Damage Through Maintenance of Glutathione Homeostasis and Inhibition of Apoptotic Progression. Environmental and Molecular Mutagenesis. 56:333-346.Full Text via DOI: 10.1002/em.21919 Web of Science: 000351777100007
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2014A 5′, 8-cyclo-2′-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β. Nucleic Acids Research (NAR). 42:13749-13763.Full Text via DOI: 10.1093/nar/gku1239 Web of Science: 000347916900033
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2014Critical role of cellular glutathione homeostasis for trivalent inorganic arsenite-induced oxidative damage in human bronchial epithelial cells. Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 770:35-45.Full Text via DOI: 10.1016/j.mrgentox.2014.04.016 Web of Science: 000340303700006
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2014Amplified Single Base-Pair Mismatch Detection via Aggregation of Exonuclease-Sheared Gold Nanoparticles. Analytical Chemistry. 86:3461-3467.Full Text via DOI: 10.1021/ac4040373 Web of Science: 000333776600030
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2014Base Excision Repair of Chemotherapeutically-Induced Alkylated DNA Damage Predominantly Causes Contractions of Expanded GAA Repeats Associated with Friedreich's Ataxia. PLoS ONE. 9.Full Text via DOI: 10.1371/journal.pone.0093464 Web of Science: 000334101100085
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2014Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion. Nucleic Acids Research (NAR). 42:3675-3691.Full Text via DOI: 10.1093/nar/gkt1372 Web of Science: 000334758600026
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2013Involvement of DNA polymerase beta overexpression in the malignant transformation induced by benzo[a]pyrene. Toxicology. 309:73-80.Full Text via DOI: 10.1016/j.tox.2013.04.017 Web of Science: 000321417100010
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2013Instability of CTG Repeats Is Governed by the Position of a DNA Base Lesion through Base Excision Repair. PLoS ONE. 8.Full Text via DOI: 10.1371/journal.pone.0056960 Web of Science: 000315561400018
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2013Trinucleotide repeat deletion via a unique hairpin bypass by DNA polymerase β and alternate flap cleavage by flap endonuclease 1. Nucleic Acids Research (NAR). 41:1684-1697.Full Text via DOI: 10.1093/nar/gks1306
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2012Deregulated expression of DNA polymerase beta is involved in the progression of genomic instability. Environmental and Molecular Mutagenesis. 53:325-333.Full Text via DOI: 10.1002/em.21697 Web of Science: 000304905000001
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2011Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding. PLoS ONE. 6.Full Text via DOI: 10.1371/journal.pone.0023679
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2010Apurinic/apyrimidinic (AP) site recognition by the 5′-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1). Proceedings of the National Academy of Sciences of the United States of America. 107:22090-22095.Full Text via DOI: 10.1073/pnas.1009182107
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2010DNA polymerase β-dependent long patch base excision repair in living cells. DNA Repair. 9:109-119.Full Text via DOI: 10.1016/j.dnarep.2009.11.002
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2009Coordination between polymerase β and FEN1 can modulate CAG repeat expansion. Journal of Biological Chemistry. 284:28352-28366.Full Text via DOI: 10.1074/jbc.M109.050286
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2007HMGB1 Is a Cofactor in Mammalian Base Excision Repair. Molecular Cell. 27:829-841.Full Text via DOI: 10.1016/j.molcel.2007.06.029
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2007OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells. Nature. 447:447-452.Full Text via DOI: 10.1038/nature05778
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2007Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase β. Journal of Biological Chemistry. 282:13532-13541.Full Text via DOI: 10.1074/jbc.M611295200
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2005DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair.. Journal of Biological Chemistry. 280:3665-3674.Full Text via DOI: 10.1074/jbc.m412922200
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2004Saccharomyces cerevisiae Flap Endonuclease 1 Uses Flap Equilibration to Maintain Triplet Repeat Stability. Molecular and Cellular Biology. 24:4049-4064.Full Text via DOI: 10.1128/MCB.24.9.4049-4064.2004
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2003Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion. Journal of Biological Chemistry. 278:13728-13739.Full Text via DOI: 10.1074/jbc.M212061200
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2002Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate. Journal of Biological Chemistry. 277:14379-14389.Full Text via DOI: 10.1074/jbc.M110662200
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2001Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage. Molecular and Cellular Biology. 21:4889-4899.Full Text via DOI: 10.1128/MCB.21.15.4889-4899.2001
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2000Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion. Journal of Biological Chemistry. 275:16420-16427.Full Text via DOI: 10.1074/jbc.M909635199
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Book
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2004Flap Endonuclease 1: A central component of DNA metabolism. Ed. 73.Full Text via DOI: 10.1146/annurev.biochem.73.012803.092453
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Book Chapter
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2017Central Steps in Mammalian BER and Regulation by PARP1. 253-280.Web of Science: 000459108000007
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2006DNA Repair Models for Understanding Triplet Repeat Instability. 667-678.Full Text via DOI: 10.1016/B978-012369462-1/50043-0
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2006Chapter 42 DNA Repair Models for Understanding Triplet Repeat Instability. 667-678.Full Text via DOI: 10.1016/b978-012369462-1/50043-0
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Conference
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2023The Novel Role of DNA Repair Polymerases in Mediating RNA Damage Repair. Environmental and Molecular Mutagenesis. 59-59.Web of Science: 001087590500100
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2023RNA synthesis by a translesion DNA polymerase mediates RNA base damage repair. Journal of Biological Chemistry. S674-S674.Full Text via DOI: 10.1016/j.jbc.2023.104242 Web of Science: 001040892101488
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2018DNA damage landscape and trinucleotide repeat instability.. Environmental and Molecular Mutagenesis. 87-87.Web of Science: 000442847800129
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2018Long intergenic non-coding RNA ROR is involved in arsenite-induced oxidative stress in HBE cells.. Environmental and Molecular Mutagenesis. 95-95.Web of Science: 000442847800146
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2018Oxidative DNA damage alters miRNA expression.. Environmental and Molecular Mutagenesis. 61-61.Web of Science: 000442847800077
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2018The deoxyribose phosphate lyase of DNA polymerase beta suppresses a processive DNA synthesis to prevent trinucleotide repeat instability.. Environmental and Molecular Mutagenesis. 89-89.Web of Science: 000442847800133
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2017Base Excision Repair in a GAA Repeat R-loop Leads to GAA Repeats Instability.. Environmental and Molecular Mutagenesis. S57-S57.Web of Science: 000408314700115
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2017Identification of miRNAs and Its Target Gene Network in Mediating Arsenite-induced Malignant Transformation in Human Bronchial Epithelial Cells by miRNA Microarray Analysis. Environmental and Molecular Mutagenesis. S70-S71.Web of Science: 000408314700154
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20175-Azido-modified pyrimidine nucleosides: Chemistry and biology. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Web of Science: 000430569105432
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20175-azidomethyl-2'-deoxyuridine triphosphate can be efficiently incorporated by a repair DNA polymerase. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Web of Science: 000430568500835
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2016Environmentally-Induced Oxidative DNA Damage Disrupts DNA Methylation Pattern in Human Breast Cancer Type 1 (BRCA1) Gene via Base Excision Repair.. Environmental and Molecular Mutagenesis. S62-S62.Web of Science: 000383587400092
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2016Functional Coordination of Dual Enzymatic Activities of DNA Polymerase beta Prevents Trinucleotide Repeat Instability.. Environmental and Molecular Mutagenesis. S70-S70.Web of Science: 000383587400116
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2016Oxidized DNA Base Lesions Promote Trinucleotide Repeat Expansion.. Environmental and Molecular Mutagenesis. S69-S69.Web of Science: 000383587400113
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2016The Deoxyribose Phosphate Lyase Activity of DNA Polymerase beta Suppresses Trinucleotide Repeat Deletions During Base Excision Repair.. Environmental and Molecular Mutagenesis. S70-S70.Web of Science: 000383587400115
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2016miRNA-155 Mediates Cellular Resistance to Arsenic Trioxide by Modulating Nrf2 Signaling Pathway.. Environmental and Molecular Mutagenesis. S72-S72.Web of Science: 000383587400125
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2015A Protective Role of Nrf2 in Arsenite-Induced Oxidative Damage is Regulated by cGMP-PKG Pathway. Environmental and Molecular Mutagenesis. S75-S75.Web of Science: 000360226400179
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2015AP Endonuclease 1 Combats the Extension of a T/G Mismatch by DNA Polymerase b in CpG Dinucleotides during Base Excision Repair. Environmental and Molecular Mutagenesis. S62-S62.Web of Science: 000360226400128
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2015DNA Polymerase beta R137Q Polymorphism Does Not Significantly Alter Trinucleotide Repeat Instability. Environmental and Molecular Mutagenesis. S63-S63.Web of Science: 000360226400130
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2015Environmentally-Induced Oxidative DNA Damage Disrupts DNA Methylation Pattern in Human Breast Cancer Type 1 (BRCA1) Gene Promoter Region. Environmental and Molecular Mutagenesis. S63-S63.Web of Science: 000360226400131
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2015Proliferating Cell Nuclear Antigen Stimulates Flap Endonuclease 1 to Modulate GAA Repeat Stability via Base Excision Repair. Environmental and Molecular Mutagenesis. S62-S62.Web of Science: 000360226400129
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2015Temozolomide Upregulates Frataxin in Friedreich's Ataxia Patient Cells via Contractions of Expanded GAA Repeats. Environmental and Molecular Mutagenesis. S62-S62.Web of Science: 000360226400127
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2015The Interaction between PCNA and FEN1 Modulates TNR Instability. Environmental and Molecular Mutagenesis. S64-S64.Web of Science: 000360226400135
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2014A 5 ', 8-deoxypurine Lesion Induces Genome Instability via DNA Polymerase beta during DNA Replication and Base Excision Repair. Environmental and Molecular Mutagenesis. S55-S55.Web of Science: 000341176900158
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2014A 5 ', 8-deoxypurine Lesion Induces Trinucleotide Repeat Deletion via DNA Polymerase beta. Environmental and Molecular Mutagenesis. S54-S54.Web of Science: 000341176900153
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2014AP Endonuclease 1 Cooperates with Flap Endonuclease 1 to Remove a Trinucleotide Repeat Hairpin.. Environmental and Molecular Mutagenesis. S54-S54.Web of Science: 000341176900152
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2014DNA Polymerase (beta) Plays a Predominant Role in Bypassing a 5 ', 8-deoxypurine Lesion during DNA Replication and Base Excision Repair. Environmental and Molecular Mutagenesis. S54-S54.Web of Science: 000341176900154
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2014MSH2-MSH3 Promotes GAA Repeat Expansion by Stimulating DNA Polymerase beta Activity during Base Excision Repair. Environmental and Molecular Mutagenesis. S55-S55.Web of Science: 000341176900155
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2014Resveratrol Inhibits Oxidative Damage Induced by Arsenic Trioxide. Environmental and Molecular Mutagenesis. S61-S61.Web of Science: 000341176900180
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2013Base Excision Repair of Oxidative DNA Damage is Coupled with Removal of a CAG Repeat Hairpin to Attenuate Trinucleotide Repeat Expansion. Environmental and Molecular Mutagenesis. S30-S30.Web of Science: 000323429400072
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2013MSH2-MSH3 Promotes GAA Repeat Expansion by Stimulating DNA Polymerase beta Activity during Base Excision Repair. Environmental and Molecular Mutagenesis. S30-S30.Web of Science: 000323429400071
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2013Trinucleotide Repeat Expansion via DNA Base Lesion Repair.. Environmental and Molecular Mutagenesis. S32-S32.Web of Science: 000323429400079
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Preprint
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Review
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2025The crosstalk of m6A-modified RNA with DNA damage repair. Trends in Biochemical Sciences. 822-833.Full Text via DOI: 10.1016/j.tibs.2025.06.012 Web of Science: 001568817300003
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2021N6-Methyladenosine, DNA Repair, and Genome Stability. Frontiers in Molecular Biosciences.Full Text via DOI: 10.3389/fmolb.2021.645823 Web of Science: 000642424000001
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2020Trinucleotide repeat instability via DNA base excision repair. DNA Repair.Full Text via DOI: 10.1016/j.dnarep.2020.102912 Web of Science: 000579361800007
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2019Replication Stress and Consequential Instability of the Genome and Epigenome. Molecules.Full Text via DOI: 10.3390/molecules24213870 Web of Science: 000498055500059
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20195′,8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance. Cells.Full Text via DOI: 10.3390/cells8060513 Web of Science: 000475309200001
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2017Dynamics of p53: A Master Decider of Cell Fate. Genes.Full Text via DOI: 10.3390/genes8020066 Web of Science: 000399058000021
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2012DNA base excision repair: a mechanism of trinucleotide repeat expansion. Trends in Biochemical Sciences. 162-172.Full Text via DOI: 10.1016/j.tibs.2011.12.002 Web of Science: 000303087600005
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2011A review of recent experiments on step-to-step "hand-off" of the DNA intermediates in mammalian base excision repair pathways. Molekulyarnaya Biologiya. 536-550.Full Text via DOI: 10.1134/S0026893311040091 Web of Science: 000293636800002
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2011A review of recent experiments on step-to-step "hand-off" of the DNA intermediates in mammalian base excision repair pathways.. Molekulyarnaya Biologiya. 586-600.
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2010Base excision repair and design of small molecule inhibitors of human DNA polymerase β. Cellular and Molecular Life Sciences. 3633-3647.Full Text via DOI: 10.1007/s00018-010-0489-1
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2010HMGB1: Roles in base excision repair and related function. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 119-130.Full Text via DOI: 10.1016/j.bbagrm.2009.11.008
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Research
principal investigator on
- N6-methyladenosine (m6A) Interplays with RNA and DNA Damage to Regulate DNA Repair awarded by Environmental Health Sciences 2023 - 2026
- A CRSIPR/dCas9-Targeted Histone Demethylation Induces GAA repeat contraction awarded by Neurological Disorders and Stroke 2023 - 2026
- 2nd Southern Genome Maintenance Conference awarded by Environmental Health Sciences 2021 - 2022
- Trinucleotide Repeat Instability via DNA Damage and Repair awarded by Environmental Health Sciences 2013 - 2021
- Mechanisms of Trinucleotide Repeat Expansion via Oxidative DNA Damage and Repair awarded by Environmental Health Sciences 2010 - 2014
- missing activity
co-principal investigator on
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Grant
- A Mechanism Based Intervention for Brevetoxin Induced Oxidative Stress awarded by National Oceanic and Atmospheric Admin 2018 - 2022
- Novel Chemotherapeutic Treatment for Prostate Cancer awarded by Community Foundation of Broward 2019 - 2020
- Investigation of a Novel Treatment for Advanced Prostate Cancer awarded by Community Foundation of Broward 2016 - 2018
subproject principal investigator on
investigator on
Contact
full name
- Yuan Liu
