Synthesis of Adenine Nucleosides with a Reactive (β-Iodovinyl)sulfone or (β-Keto)sulfone Group at the C2 Position and Their Polymerase-Catalyzed Incorporation into DNA Article

Howlader, A Hasan, Fernandez, Richard, Tsegay, Pawlos S et al. (2025). Synthesis of Adenine Nucleosides with a Reactive (β-Iodovinyl)sulfone or (β-Keto)sulfone Group at the C2 Position and Their Polymerase-Catalyzed Incorporation into DNA . 30(6), 10.3390/molecules30061358

cited authors

  • Howlader, A Hasan; Fernandez, Richard; Tsegay, Pawlos S; Liu, Yuan; Wnuk, Stanislaw F

authors

publication date

  • March 18, 2025

keywords

  • (beta-halovinyl)sulfones
  • (beta-keto)sulfones
  • 5'-TRIPHOSPHATES
  • beta-sulfonylvinylamines
  • ALKYNES
  • BETA-KETO-SULFONES
  • Biochemistry & Molecular Biology
  • C5 POSITION
  • Chemistry
  • Chemistry, Multidisciplinary
  • DISCOVERY
  • DNA polymerases
  • EFFICIENT SYNTHESIS
  • HALOSULFONYLATION
  • IODOVINYL SULFONES
  • Life Sciences & Biomedicine
  • NUCLEOTIDES
  • Physical Sciences
  • Science & Technology
  • VINYL SULFONES
  • adenosine-2-carboxylic acid
  • halosulfonylation of alkynes
  • nucleosides
  • phosphorylation
  • purines

Digital Object Identifier (DOI)

publisher

  • MDPI

volume

  • 30

issue

  • 6