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Fierst, Janna
Positions
Associate Professor
,
Biological Sciences
,
College of Arts, Sciences & Education
jfierst@fiu.edu
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Overview
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Research
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Overview
biography
Research in my lab focuses on understanding the rules of genome evolution. We study how life is organized, structured, and changes and how we can use theory, computational models and bioinformatic analyses to understand it.
research interests
Evolutionary Biology; Computational Genomics; Complex Systems; Bioinformatics; Diphenylarsinic Acid; Pelobacter Acetylenicus; Soil
Scholarly & Creative Works
selected scholarly works & creative activities
Article
2024
Regulatory logic and transposable element dynamics in nematode worm genomes.
Full Text via DOI:
10.1101/2024.09.15.613132
2024
Identifying transgene insertions in
Caenorhabditis elegans
genomes with Oxford Nanopore sequencing
.
PEERJ
. 12.
Full Text via DOI:
10.7717/peerj.18100
Web of Science:
001316501400008
2023
Acetylenotrophic and Diazotrophic Bradyrhizobium sp. Strain I71 from Trichloroethylene-Contaminated Soils
Full Text via DOI:
10.3897/aca.6.e109201
2023
Genome Size Changes by Duplication, Divergence, and Insertion in Caenorhabditis Worms
.
MOLECULAR BIOLOGY AND EVOLUTION
. 40.
Full Text via DOI:
10.1093/molbev/msad039
Web of Science:
000950310700004
2023
Dauer fate in a Caenorhabditis elegans Boolean network model
.
PEERJ
. 11.
Full Text via DOI:
10.7717/peerj.14713
Web of Science:
000925361000003
2022
Acetylenotrophic and Diazotrophic
Bradyrhizobium
sp. Strain I71 from TCE-Contaminated Soils
.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
. 88.
Full Text via DOI:
10.1128/aem.01219-22
Web of Science:
000876970000001
2022
Slow Recovery from Inbreeding Depression Generated by the Complex Genetic Architecture of Segregating Deleterious Mutations
.
MOLECULAR BIOLOGY AND EVOLUTION
. 39.
Full Text via DOI:
10.1093/molbev/msab330
Web of Science:
000771141500012
2022
Complete Genome Sequence of Rhodococcus opacus Strain MoAcy1 (DSM 44186), an Aerobic Acetylenotroph Isolated from Soil
Full Text via DOI:
10.1128/MRA.00814-21
Web of Science:
000746032300029
2021
Optimizing experimental design for genome sequencing and assembly with Oxford Nanopore Technologies
Full Text via DOI:
10.46471/gigabyte.27
2021
Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in
Drosophila
.
G3-GENES GENOMES GENETICS
. 11.
Full Text via DOI:
10.1093/g3journal/jkab116
Web of Science:
000735821500011
2021
Complex pleiotropic genetic architecture of evolved heat stress and oxidative stress resistance in the nematode Caenorhabditis remanei
.
G3-GENES GENOMES GENETICS
. 11.
Full Text via DOI:
10.1093/g3journal/jkab045
Web of Science:
000651852100011
2021
Syntrophotalea acetylenivorans
sp. nov., a diazotrophic, acetylenotrophic anaerobe isolated from intertidal sediments
.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
. 71.
Full Text via DOI:
10.1099/ijsem.0.004698
Web of Science:
000639142700023
2020
Caenorhabditis elegans
dauers vary recovery in response to bacteria from natural habitat
.
ECOLOGY AND EVOLUTION
. 10:9886-9895.
Full Text via DOI:
10.1002/ece3.6646
Web of Science:
000562028100001
2020
De Novo
Genome Assemblies for Three North American Bumble Bee Species:
Bombus bifarius
,
Bombus vancouverensis
, and
Bombus vosnesenskii
.
G3-GENES GENOMES GENETICS
. 10:2585-2592.
Full Text via DOI:
10.1534/g3.120.401437
Web of Science:
000560448200003
2020
Environmental stress maintains trioecy in nematode worms
.
EVOLUTION
. 74:518-527.
Full Text via DOI:
10.1111/evo.13932
Web of Science:
000512354500001
2017
Decontaminating eukaryotic genome assemblies with machine learning
.
BMC BIOINFORMATICS
. 18.
Full Text via DOI:
10.1186/s12859-017-1941-0
Web of Science:
000416904100001
2017
Detection of Diazotrophy in the Acetylene-Fermenting Anaerobe
Pelobacter
sp Strain SFB93
.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
. 83.
Full Text via DOI:
10.1128/AEM.01198-17
Web of Science:
000408259000026
2017
Complete Genome Sequence of the Acetylene-Fermenting Pelobacter sp. Strain SFB93
Full Text via DOI:
10.1128/genomeA.01573-16
Web of Science:
000460679700013
2017
Complete Genome Sequences of Two Acetylene-Fermenting
Pelobacter acetylenicus
Strains
Full Text via DOI:
10.1128/genomeA.01572-16
Web of Science:
000460679700012
2017
Metagenome-Assembled Draft Genome Sequence of a Novel Microbial
Stenotrophomonas maltophilia
Strain Isolated from
Caenorhabditis remanei
Tissue
Full Text via DOI:
10.1128/genomeA.01646-16
Web of Science:
000460681200024
2016
Rebalancing redox to improve biobutanol production by clostridium tyrobutyricum
Full Text via DOI:
10.3390/bioengineering3010002
2015
Reproductive Mode and the Evolution of Genome Size and Structure in
Caenorhabditis
Nematodes
.
PLOS GENETICS
. 11.
Full Text via DOI:
10.1371/journal.pgen.1005323
Web of Science:
000357341600048
2015
Modeling the Evolution of Complex Genetic Systems: The Gene Network Family Tree
Full Text via DOI:
10.1002/jez.b.22597
Web of Science:
000346267300001
2013
Female mating preferences determine system-level evolution in a gene network model
.
GENETICA
. 141:157-170.
Full Text via DOI:
10.1007/s10709-013-9714-9
Web of Science:
000323902200003
2013
PROPERTIES OF SPONTANEOUS MUTATIONAL VARIANCE AND COVARIANCE FOR WING SIZE AND SHAPE IN DROSOPHILA MELANOGASTER
.
EVOLUTION
. 67:1116-1130.
Full Text via DOI:
10.1111/j.1558-5646.2012.01838.x
Web of Science:
000317133800016
2012
Variance in Epistasis Links Gene Regulation and Evolutionary Rate in the Yeast Genetic Interaction Network
.
GENOME BIOLOGY AND EVOLUTION
. 4:1080-1087.
Full Text via DOI:
10.1093/gbe/evs083
Web of Science:
000313215500002
2011
A history of phenotypic plasticity accelerates adaptation to a new environment
Full Text via DOI:
10.1111/j.1420-9101.2011.02333.x
Web of Science:
000293910500016
2011
Sexual Dimorphism Increases Evolvability in a Genetic Regulatory Network
Full Text via DOI:
10.1007/s11692-010-9103-6
2010
Spatial distribution and reproductive phenology of sexual and asexual
Mastocarpus papillatus
(Rhodophyta)
.
PHYCOLOGIA
. 49:274-282.
Full Text via DOI:
10.2216/PH09-41.1
Web of Science:
000277475400007
2010
GENETIC ARCHITECTURE AND POSTZYGOTIC REPRODUCTIVE ISOLATION: EVOLUTION OF BATESON-DOBZHANSKY-MULLER INCOMPATIBILITIES IN A POLYGENIC MODEL
.
EVOLUTION
. 64:675-693.
Full Text via DOI:
10.1111/j.1558-5646.2009.00861.x
Web of Science:
000274713800006
2009
SEXUAL SELECTION ACCELERATES THE ELIMINATION OF A DELETERIOUS MUTANT IN
DROSOPHILA MELANOGASTER
.
EVOLUTION
. 63:324-333.
Full Text via DOI:
10.1111/j.1558-5646.2008.00551.x
Web of Science:
000263254000003
2005
Fertilization success can drive patterns of phase dominance in complex life histories
.
JOURNAL OF PHYCOLOGY
. 41:238-249.
Full Text via DOI:
10.1111/j.1529-8817.2005.04024.x
2002
Spatial and Temporal Distribution of Life History Variants in the Red Alga, Mastocarpus Papillatus
.
JOURNAL OF PHYCOLOGY
. 38:9-9.
Full Text via DOI:
10.1046/j.1529-8817.38.s1.26.x
Other Scholarly Work
2020
Genome Evolution: On the Road to Parasitism
.
CURRENT BIOLOGY
. R272-R274.
Full Text via DOI:
10.1016/j.cub.2020.01.088
Web of Science:
000522553700015
2015
Erratum to: Reproductive Mode and the Evolution of Genome Size and Structure in Caenorhabditis Nematodes (PLoS Genet, (2015), 11, 9)
.
PLOS GENETICS
.
Full Text via DOI:
10.1371/journal.pgen.1005497
Preprint
2022
Dauer fate in a
Caenorhabditis elegans
Boolean network model
Full Text via DOI:
10.1101/2022.08.18.504430
2020
Caenorhabditis elegans
dauers vary recovery in response to bacteria from natural habitat
Full Text via DOI:
10.1101/2020.04.01.020693
2020
Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in
Drosophila
Full Text via DOI:
10.1101/2020.09.21.307017
2020
Optimizing experimental design for genome sequencing and assembly with Oxford Nanopore Technologies
Full Text via DOI:
10.1101/2020.05.05.079327
2019
Complex pleiotropic genetic architecture of evolved heat stress and oxidative stress resistance in the nematode
Caenorhabditis remanei
Full Text via DOI:
10.1101/515320
2019
Environmental stress maintains trioecy in nematode worms
Full Text via DOI:
10.1101/862664
2019
Slow recovery from inbreeding depression generated by the complex genetic architecture of segregating deleterious mutations
Full Text via DOI:
10.1101/862631
Genome size changes by duplication, insertion and divergence in Caenorhabditis worms
Full Text via DOI:
10.1101/2022.05.20.492698
Review
2021
REVIEW OF THE DAUER HYPOTHESIS: WHAT NON-PARASITIC SPECIES CAN TELL US ABOUT THE EVOLUTION OF PARASITISM
.
JOURNAL OF PARASITOLOGY
. 717-725.
Full Text via DOI:
10.1645/21-40
Web of Science:
000696462900002
2018
Acetylenotrophy: a hidden but ubiquitous microbial metabolism?
.
FEMS MICROBIOLOGY ECOLOGY
.
Full Text via DOI:
10.1093/femsec/fiy103
Web of Science:
000441198800001
2015
Using linkage maps to correct and scaffold
de novo
genome assemblies: methods, challenges, and computational tools
.
FRONTIERS IN GENETICS
.
Full Text via DOI:
10.3389/fgene.2015.00220
Web of Science:
000359647500001
Research
principal investigator on
Structural variants and the locus of evolution
awarded by
General Medical Sciences
2022 - 2027
CAREER: Reproductive mode and horizontal gene transfer in nematode worms: Training early career researchers in computational evolutionary biology
awarded by
National Science Foundation
2022 - 2025
Understanding the Rules of Life: Epigenetics 2: Collaborative research: Bumble bee cold tolerance across elevations- From epigenotype to phenotype across space, time, and levels of biological organization
awarded by
National Science Foundation
2022 - 2024
Contact
full name
Janna
Fierst
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ORCID iD
https://orcid.org/0000-0002-3639-8829
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