FIU Discovery

How Robust is the Evidence for a Role of Oxidative Stress in Autism Spectrum Disorders and Intellectual Disabilities?.  Journal of Autism and Developmental Disorders.  51:1428-1445.

Influence of skin melanisation and ultraviolet radiation on biomarkers of systemic oxidative stress.  Free Radical Biology and Medicine.  160:40-46.

The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors.  Molecular Cancer Therapeutics.  19:432-446.

DNA Crosslinkomics: A Tool for the Comprehensive Assessment of Interstrand Crosslinks Using High Resolution Mass Spectrometry.  Analytical Chemistry.  91:15193-15203.

Evaluation of the Major Steps in the Conventional Protocol for the Alkaline Comet Assay.  International Journal of Molecular Sciences.  20.

Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes.  International Journal of Molecular Sciences.  20.

Mycoplasma infection of cultured cells induces oxidative stress and attenuates cellular base excision repair activity.  Mutation Research - Genetic Toxicology and Environmental Mutagenesis.  845.

Clinical relevance of guanine-derived urinary biomarkers of oxidative stress, determined by LC-MS/MS.  Redox Biology.  20:556-565.

Utilization of Complementary and Alternative Therapies in Youth with Developmental Disabilities.  Evidence-Based Complementary and Alternative Medicine.  2019.

Urinary DNA adductomics - A novel approach for exposomics.  Environment International.  121:1033-1038.

Children are particularly vulnerable to environmental tobacco smoke exposure: Evidence from biomarkers of tobacco-specific nitrosamines, and oxidative stress.  Environment International.  120:238-245.

Fractional Sunburn Threshold UVR Doses Generate Equivalent Vitamin D and DNA Damage in Skin Types I-VI but with Epidermal DNA Damage Gradient Correlated to Skin Darkness.  Journal of Investigative Dermatology.  138:2244-2252.

Direct-acting DNA ethylating agents associated with tobacco use primarily originate from the tobacco itself, not combustion.  Journal of Hazardous Materials.  358:397-404.

Novel approach to integrated DNA adductomics for the assessment of in vitro and in vivo environmental exposures.  Archives of Toxicology.  92:2665-2680.

Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes.  Scientific Reports.  8.

Concurrent beneficial (vitamin D production) and hazardous (cutaneous DNA damage) impact of repeated low-level summer sunlight exposures.  British Journal of Dermatology.  175:1320-1328.

Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine.  Free Radical Biology and Medicine.  99:385-391.

Urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine analysis by an improved ELISA: An inter-laboratory comparison study.  Free Radical Biology and Medicine.  95:169-179.

8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine concentrations in various human body fluids: implications for their measurement and interpretation.  Archives of Toxicology.  89:201-210.

Rescue of cells from apoptosis increases DNA repair in UVB exposed cells: implications for the DNA damage response.  Toxicology Research.  4:725-738.

Novel method for the high-throughput processing of slides for the comet assay.  Scientific Reports.  4.

Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories.  Mutagenesis.  29:241-249.

Urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine values determined by a modified ELISA improves agreement with HPLC-MS/MS.  Biochemical and Biophysical Research Communications.  440:725-730.

Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2′-deoxyguanosine.  Antioxidants and Redox Signaling.  18:2377-2391.

An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells.  Mutagenesis.  28:279-286.

Does Nausea and Vomiting of Pregnancy Play a Role in the Association Found Between Maternal Caffeine Intake and Fetal Growth Restriction?.  Maternal and Child Health Journal.  17:601-608.

Inter-laboratory variation in DNA damage using a standard comet assay protocol.  Mutagenesis.  27:665-672.

Rapid measurement of 8-oxo-7,8-dihydro-2′-deoxyguanosine in human biological matrices using ultra-high-performance liquid chromatography-tandem mass spectrometry.  Free Radical Biology and Medicine.  52:2057-2063.

Increased Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Expression Mediates Intrinsic Airway Smooth Muscle Hypercontractility in Asthma.  American Journal of Respiratory and Critical Care Medicine.  185:267-274.

Immuno-slot blot assay for detection of UVR-mediated DNA damage.  Methods in molecular biology (Clifton, N.J.).  920:163-175.

Simplified method for the collection, storage, and comet assay analysis of DNA damage in whole blood.  Free Radical Biology and Medicine.  51:719-725.

Non-invasive Assessment of Oxidatively Damaged DNA: Liquid Chromatography-Tandem Mass Spectrometry Analysis of Urinary 8-Oxo-7,8-Dihydro-2 '-Deoxyguanosine.  Methods in molecular biology (Clifton, N.J.).  682:279-+.

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans.  Journal of Clinical Investigation.  120:4220-4235.

Interpretation of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine is adversely affected by methodological inaccuracies when using a commercial ELISA.  Free Radical Biology and Medicine.  48:1460-1464.

Caffeine intake during pregnancy, late miscarriage and stillbirth.  European Journal of Epidemiology (EJE).  25:275-280.

Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine as a noninvasive biomarker of oxidative stress.  The FASEB Journal.  24:1249-1260.

Analysis of Urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine by Liquid Chromatography-Tandem Mass Spectrometry.  Methods in molecular biology (Clifton, N.J.).  610:341-351.

First-trimester increase in oxidative stress and risk of small-for-gestational-age fetus.  BJOG: An International Journal of Obstetrics and Gynaecology.  116:637-642.

Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells.  Toxicology Letters.  185:23-31.

Gene expression profiling reveals new protective roles for vitamin C in human skin cells.  Free Radical Biology and Medicine.  46:78-87.

Interlaboratory comparison of methodologies for the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine.  Biomarkers.  14:103-110.

Combination of azathioprine and UVA irradiation is a major source of cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine.  DNA Repair.  7:1982-1989.

Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker?.  European Journal of Nutrition.  47:19-28.

Analysis of urinary 8-oxo-7,8-dihydro-purine-2'-deoxyribonucleosides by LC-MS/MS and improved ELISA.  Free Radical Research.  42:831-840.

Antiserum detection of reactive carbonyl species-modified DNA in human colonocytes.  Free Radical Research.  42:344-353.

Evidence that oxidative stress is a risk factor for the development of squamous cell carcinoma in renal transplant patients.  Free Radical Biology and Medicine.  43:1328-1334.

Neutrophils in induced sputum from healthy children: Role of interleukin-8 and oxidative stress.  Respiratory Medicine.  101:2108-2112.

A comparison of the gene expression profiles of CRL-1807 colonocytes exposed to endogenous AAPH-generated peroxides and exogenous peroxides from heated oil.  Redox Report.  12:86-90.

Evaluation of enzyme-linked immunosorbent assay and liquid chromatography-tandem mass spectrometry methodology for the analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine in saliva and urine.  Free Radical Biology and Medicine.  41:1829-1836.

Evidence for attenuated cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine removal in cancer patients.  Biological Chemistry.  387:393-400.

Immunochemical detection of UV-induced DNA damage and repair..  Methods in molecular biology (Clifton, N.J.).  314:215-228.

DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine.  MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS.  574:58-66.

Plasma levels of the endocannabinoid anandamide in women - A potential role in pregnancy maintenance and labor?.  Journal of Clinical Endocrinology and Metabolism (JCEM).  89:5482-5487.

Immunochemical detection of UV-induced DNA damage and repair.  Journal of Immunological Methods.  280:125-133.

Quantification of UVR-induced DNA damage: global- versus gene-specific levels of thymine dimers.  Journal of Immunological Methods.  277:27-37.

Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal.  Laboratory Investigation.  83:241-250.

17 beta-oestradiol attenuates nucleotide excision repair.  FEBS Letters.  535:153-158.

Deoxycytidine glyoxal: Lesion induction and evidence of repair following vitamin C supplementation in vivo.  Free Radical Biology and Medicine.  34:218-225.

Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories:: an approach to consensus.  Carcinogenesis.  23:2129-2133.

DNA repair: Insights from urinary lesion analysis.  Free Radical Research.  36:929-932.

Urinary analysis of oxidative DNA damage. Lessons from lesions.  GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA.  137:239-256.

Monoclonal antibody to single-stranded DNA: A potential tool for DNA repair studies.  Biochemical and Biophysical Research Communications.  284:232-238.

Induction and excretion of ultraviolet-induced 8-oxo-2′-deoxyguanosine and thymine dimers in vivo:: Implications for PUVA.  Journal of Investigative Dermatology.  116:281-285.

Aberrant processing of oxidative DNA damage in systemic lupus erythematosus.  Biochemical and Biophysical Research Communications.  273:894-898.

The effects of vitamin C supplementation on protein oxidation in healthy volunteers.  Biochemical and Biophysical Research Communications.  273:729-735.

Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage.  Free Radical Research.  32:333-341.

Immunochemical quantitation of UV-induced oxidative and dimeric DNA damage to human keratinocytes.  Free Radical Research.  33:369-+.

Urinary thymine dimers and 8-oxo-2′-deoxyguanosine in psoriasis.  FEBS Letters.  460:549-553.

Discrepancies in the measurement of UVC-induced 8-oxo-2′-deoxyguanosine: Implications for the analysis of oxidative DNA damage.  Biochemical and Biophysical Research Communications.  259:374-378.

Novel repair action of vitamin C upon in vivo oxidative DNA damage.  FEBS Letters.  439:363-367.

Further evidence for a possible role of conformation in the immunogenicity and antigenicity of the oxidative DMA lesion, 8-oxo-2′deoxyguanosine.  Free Radical Research.  28:459-469.

Immunogenicity of DNA damaged by reactive oxygen species - Implications for anti-DNA antibodies in lupus.  Free Radical Biology and Medicine.  22:151-159.

Quantitative determination of cyclobutane thymine dimers in DNA by stable isotope-dilution mass spectrometry.  Photochemistry and Photobiology.  64:310-315.

Light-based methods for whole blood bacterial inactivation enabled by a recirculating flow system.  Photochemistry and Photobiology.  94:744-751.

Lipid- and Protein-Mediated Oxidative Damage to DNA.  201-220.

Dietary anti- and prooxidants: Their impact on oxidative DNA damage and cancer risk.  137-155.

Neurodegenerative disease and the repair of oxidatively damaged DNA.  131-140.

Automated quantification of DNA damage via deep transfer learning based analysis of comet assay images.  Proceedings of SPIE - The International Society for Optical Engineering.

Has the duration and temperature of lysis buffer been minimized for the comet assay?.  The FASEB Journal.

COMPAC-50, High-Throughput Comet Assay Tank.  Environmental and Molecular Mutagenesis. S65-S65.

Redox-regulation of DNA repair (Reprinted from Thiol Metabolism and Redox Regulation of Cellular Functions).  BioFactors. 315-324.

Cell cycle and dose dependence of DNA damage and p53 expression following UVA irradiation.  Biochemical Society Transactions. 481.

DNA nucleotide excision repair, where do all the cyclobutane pyrimidine dimers go?.  Cell Cycle. 1642-1642.

Recommendations for Standardized Description of and Nomenclature Concerning Oxidatively Damaged Nucleobases in DNA.  Chemical Research in Toxicology. 705-707.

Case 3-2007: A boy with respiratory insufficiency.  New England Journal of Medicine. 2329-2330.

Antioxidant properties of vitamin C: new issues..  Cancer Epidemiology. 565-566.

Development of a DNA Adductome Mass Spectral Database.  Chemical Research in Toxicology. 852-854.

Editorial: Mass Spectrometry for Adductomic Analysis.  Frontiers in Chemistry.

Mycosporine-like amino acids: does Nature make a better sunscreen?.  British Journal of Dermatology. 1239-1240.

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) (vol 13, pg 94, 2017).  Redox Biology. 694-696.

Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes (vol 8, 2018).  Scientific Reports.

Measurement of 8-oxo-7,8-dihydro-2 '-deoxyguanosine in urine by an improved ELISA.  Toxicology Letters. S52-S52.

Oxidative stress and feto-maternal well-being in pregnancy.  Toxicology Letters. S52-S52.

Inter-laboratory variation in DNA damage using a standard comet assay protocol (vol 27, pg 665, 2012).  Mutagenesis. 241-241.

Special issue on DNA oxidation: Mechanisms, measurement and consequences.  Free Radical Research. 365-366.

Caffeine Intake During Pregnancy, Late Miscarriage, and Stillbirth.  Obstetrical and Gynecological Survey. 492-494.

A commentary on "Urea, the most abundant component in urine, cross-reacts with a commercial 8-OH-dG ELISA kit and contributes to overestimation of urinary 8-OH-dG". What is ELISA detecting?.  Free Radical Biology and Medicine. 30-31.

8-Oxo-deoxyguanosine: Reduce, reuse, recycle?.  Proceedings of the National Academy of Sciences of the United States of America. 13535-13536.

Quantification of UVR-induced DNA damage: global-verus gene-specific levels of thymine dimers (vol 277, pg 27, 2003).  Journal of Immunological Methods. 211-211.

Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results.  Nature Protocols. 3817-3826.

Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy.  Biochimica et Biophysica Acta - Reviews on Cancer. 29-41.

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).  Redox Biology. 94-162.

Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids.  Free Radical Research. 367-381.

Harmonising measurements of 8-oxo-7,8-dihydro-2′-deoxyguanosine in cellular DNA and urine.  Free Radical Research. 541-553.

Salvage of oxidized guanine derivatives in the (2′-deoxy)ribonucleotide pool as source of mutations in DNA.  Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 11-17.

DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides.  Mutagenesis. 433-442.

Sources of Extracellular, Oxidatively-Modified DNA Lesions: Implications for Their Measurement in Urine.  Journal of Clinical Biochemistry and Nutrition. 255-270.

Measurement and meaning of oxidatively modified DNA lesions in urine.  Cancer Epidemiology, Biomarkers and Prevention. 3-14.

Does measurement of oxidative damage to DNA have clinical significance?.  Clinica Chimica Acta. 30-49.

Oxidative damage to DNA in non-malignant disease: biomarker or biohazard?.  Genome Dynamics. 53-66.

Oxidative DNA damage and disease: induction, repair and significance.  Mutation Research - Reviews in Mutation Research. 1-61.

Factors contributing to the outcome of oxidative damage to nucleic acids.  BioEssays. 533-542.

Oxidative DNA damage: mechanisms, mutation, and disease.  The FASEB Journal. 1195-1214.

Progress in the analysis of urinary oxidative DNA damage.  Free Radical Biology and Medicine. 1601-1614.

Urinary 8-oxo-2′-deoxyguanosine: Redox regulation of DNA repair in vivo?.  Free Radical Biology and Medicine. 875-885.

Role of dietary antioxidants in the prevention of in vivo oxidative DNA damage.  Nutrition Research Reviews. 19-41.

Biomarkers.  Molecular Aspects of Medicine. 101-208.

Urinary 8-oxo-2′-deoxyguanosine - Source, significance and supplements.  Free Radical Research. 381-397.

Urinary measurement of 8-oxodG, 8-oxoGua, and 5HMUra: A noninvasive assessment of oxidative damage to DNA.  Antioxidants and Redox Signaling. 1011-1019.