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JOURNAL OF BIOLOGICAL CHEMISTRY
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Abstract 1370 Revealing the nucleic acid interactions of human topoisomerase 3 beta, a unique dual-acting topoisomerase, and discovering its inhibitors
. 300:106882.
2024
Abstract 1490 Identification of flexible hinge region residues in bacterial topoisomerase IA
. 300:106904.
2024
Abstract 2287 The arsenic-containing compound 2-amino-4-arsinobutyric acid exhibits anti-cancer effects by inhibiting glutaminase
. 300:106125.
2024
Plasmodium parasitophorous vacuole membrane protein Pfs16 promotes malaria transmission by silencing mosquito immunity
. 299.
2023
R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities
. 295:13902-13913.
2020
Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation
. 295:7669-7685.
2020
Glycoengineering of chimeric antigen receptor (CAR) T-cells to enforce E-selectin binding
. 294:18465-18474.
2019
Protamines from liverwort are produced by post-translational cleavage and C-terminal di-aminopropanelation of several male germ-specific H1 histones
. 294:16364-16373.
2019
N
-Glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2)
. 294:13117-13130.
2019
Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival
. 294:11354-11368.
2019
Crystal structure of a novel domain of the motor subunit of the Type i restriction enzyme EcoR124 involved in complex assembly and DNA binding
. 293:15043-15054.
2018
Communication between N terminus and loop2 tunes Orai activation
. 293:1271-1285.
2018
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer
. 292:16351-16359.
2017
Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side
. 292:12895-12905.
2017
Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina
. 291:4698-4710.
2016
Structural insights into the assembly of the adeno-associated virus type 2 Rep68 protein on the integration site AAVS1
. 290:27487-27499.
2015
Role of c-Met/Phosphatidylinositol 3-Kinase (PI3k)/Akt Signaling in Hepatocyte Growth Factor (HGF)- mediated Lamellipodia Formation, Reactive Oxygen Species (ROS) Generation, and Motility of Lung Endothelial Cells
. 289:13476-13491.
2014
Activity of ADAM17 (a disintegrin and metalloprotease 17) is regulated by its noncatalytic domains and secondary structure of its substrates
. 288:22871-22879.
2013
Enhancement of Human DNA Polymerase η Activity and Fidelity Is Dependent Upon a Bipartite Interaction with the Werner Syndrome Protein
. 287:42312-42323.
2012
Discovery of novel inhibitors of a disintegrin and metalloprotease 17 (ADAM17) using glycosylated and non-glycosylated substrates
. 287:36473-36487.
2012
Proteomic identification of glycosylphosphatidylinositol anchor-dependent membrane proteins elevated in breast carcinoma
. 287:25230-25240.
2012
Corneal antifibrotic switch identified in genetic and pharmacological deficiency of vimentin
. 287:989-1006.
2012
Sugar binding residue affects apparent Na
+
affinity and transport stoichiometry in mouse sodium/glucose cotransporter type 3B
. 286:7975-7982.
2011
Natural and engineered photoactivated nucleotidyl cyclases for optogenetic applications
. 285:41501-41508.
2010
β-Actin Association with Endothelial Nitric-oxide Synthase Modulates Nitric Oxide and Superoxide Generation from the Enzyme
. 285:4319-4327.
2010
A synthetic combinatorial strategy for developing α-conotoxin analogs as potent α
7
nicotinic acetylcholine receptor antagonists
. 285:1809-1821.
2010
Coordination between polymerase β and FEN1 can modulate CAG repeat expansion
. 284:28352-28366.
2009
Structural and Functional Characterizations of SsgB, a Conserved Activator of Developmental Cell Division in Morphologically Complex Actinomycetes
. 284:25268-25279.
2009
Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase
. 284:16693-16703.
2009
Role of Bound Zn(II) in the CadC Cd(II)/Pb(II)/Zn(II)-responsive Repressor
. 284:14958-14965.
2009
Protein kinase A-mediated gating of neuregulin-dependent ErbB2-ErbB3 activation underlies the synergistic action of cAMP on schwann cell proliferation
. 283:34087-34100.
2008
Receptor tyrosine phosphatase β (RPTPβ) activity and signaling are attenuated by glycosylation and subsequent cell surface galectin-1 binding
. 283:33026-33035.
2008
Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression
. 283:15845-15852.
2008
The hominoid-specific oncogene TBC1d3 activates ras and modulates epidermal growth factor receptor signaling and trafficking
. 283:13233-13242.
2008
An arsenate-activated glutaredoxin from the arsenic hyperaccumulator fern
Pteris vittata
L. regulates intracellular arsenite
. 283:6095-6101.
2008
Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase β
. 282:13532-13541.
2007
Biochemical, molecular, and functional characterization of PISCF-allatostatin, a regulator of juvenile hormone biosynthesis in the mosquito
Aedes aegypti
. 281:34048-34055.
2006
Cys-113 and Cys-422 form a high affinity metalloid binding site in the ArsA ATPase
. 281:9925-9934.
2006
Hypothyroid phenotype is contributed by mitochondrial complex I inactivation due to translocated neuronal nitric-oxide synthase
. 281:4779-4786.
2006
Identification of a novel recognition sequence for fibronectin within the NH
2
-terminal β-sandwich domain of tissue transglutaminase
. 280:23675-23683.
2005
Inhibition of protein-tyrosine phosphatases by mild oxidative stresses is dependent on
S
-nitrosylation
. 280:14453-14461.
2005
DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair.
. 280:3665-3674.
2005
Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors
. 279:48168-48176.
2004
Coupling DNA supercoiling to transcription in defined protein systems
. 279:47564-47571.
2004
The tryptophan-rich motifs of the thrombospondin type 1 repeats bind VLAL motifs in the latent transforming growth factor-β complex
. 279:47633-47642.
2004
Protein kinase C θ inhibits insulin signaling by phosphorylating IRS1 at Ser
1101
. 279:45304-45307.
2004
Site-directed mutagenesis of residues involved in G strand DNA binding by Escherichia coli DNA topoisomerase I
. 279:39207-39213.
2004
Leishmania major
LmACR2 is a pentavalent antimony reductase that confers sensitivity to the drug Pentostam
. 279:37445-37451.
2004
Molecular interactions that confer latency to transforming growth factor-β
. 279:38032-38039.
2004
Inhibition of furin by polyarginine-containing peptides: Nanomolar inhibition by nona-D-arginine
. 279:36788-36794.
2004
Drug uptake and modulation of drug resistance in
Leishmania
by an aquaglyceroporin
. 279:31010-31017.
2004
As(III) and Sb(III) uptake by G1pF and efflux by ArsB in
Escherichia coli
. 279:18334-18341.
2004
Arsenic trioxide uptake by hexose permeases in
Saccharomyces cerevisiae
. 279:17312-17318.
2004
Structure-function analysis of the reactive site in the first Kunitz-type domain of human tissue factor pathway inhibitor-2
. 279:17500-17507.
2004
Flexibility at Gly-194 is required for DNA cleavage and relaxation activity of Escherichia coli DNA topoisomerase I
. 279:8648-8654.
2004
Reversible Inhibitors of λ Integrase-mediated Recombination Efficiently Trap Holliday Junction Intermediates and Form the Basis of a Novel Assay for Junction Resolution
. 279:3472-3483.
2004
The Src homology 2 domain of Rin1 mediates its binding to the epidermal growth factor receptor and regulates receptor endocytosis
. 278:32027-32036.
2003
Direct interaction between
Escherichia coli
RNA polymerase and the zinc ribbon domains of DNA topoisomerase I
. 278:30705-30710.
2003
Repressors of androgen and progesterone receptor action
. 278:31136-31148.
2003
Directed evolution of a yeast arsenate reductase into a protein-tyrosine phosphatase
. 278:24476-24480.
2003
Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion
. 278:13728-13739.
2003
Two-dimensional NMR study of the heme active site structure of chloroperoxidase
. 278:7765-7774.
2003
Biochemical characterization of CopA, the
Escherichia coli
Cu(I)-translocating P-type ATPase
. 277:46987-46992.
2002
The soft metal ion binding sites in the Staphylococcus aureus pI258 CadC Cd(II)/Pb(II)/Zn(II)-responsive repressor are formed between subunits of the homdimer
. 277:40930-40936.
2002
1,25-Dihydroxyvitamin D down-regulates cell membrane growth- and nuclear growth-promoting signals by the epidermal growth factor receptor
. 277:38965-38971.
2002
Evidence for cooperativity between the four binding sites of dimeric ArsD, an As(III)-responsive transcriptional regulator
. 277:25992-26002.
2002
Unisite and multisite catalysis in the ArsA ATPase
. 277:23815-23820.
2002
Activation of constitutive nitric-oxide sythase activity is an early signaling event induced by ionizing radiation
. 277:15400-15406.
2002
Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate
. 277:14379-14389.
2002
Bicarbonate enhances peroxidase activity of Cu,Zn-superoxide dismutase: Role of carbonate anion radical and scavenging of carbonate anion radical by metalloporphyrin antioxidant enzyme mimetics
. 277:1013-1020.
2002
Residue 457 Controls Sugar Binding and Transport in the Na
+
/Glucose Cotransporter
. 276:49188-49194.
2001
Differential L-selectin binding activities of human hematopoietic cell L-selectin ligands, HCELL and PSGL-1
. 276:47623-47631.
2001
Phosphatidylinositol-4-phosphate 5-Kinase-1β Is Essential for Epidermal Growth Factor Receptor-mediated Endocytosis
. 276:47212-47216.
2001
The phosphatase C(
X
)
5
R motif is required for catalytic activity of the
Saccharomyces cerevisiae
Acr2p arsenate reductase
. 276:34738-34742.
2001
Conformational changes in four regions of the
Escherichia coli
ArsA ATPase link ATP hydrolysis to ion translocation
. 276:30414-30422.
2001
The
Leishmania
ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase
. 276:26301-26307.
2001
Role of cysteinyl residues in sensing Pb(II), Cd(II), and Zn(II) by the plasmid pI258 CadC repressor
. 276:14955-14960.
2001
A kinetic model for the action of a resistance efflux pump
. 276:6378-6391.
2001
Polyarginines are potent furin inhibitors
. 275:36741-36749.
2000
Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases
. 275:32289-32298.
2000
A novel membrane-anchored Rab5 interacting protein required for homotypic endosome fusion
. 275:24661-24669.
2000
Purification and characterization of Acr2p, the
Saccharomyces cerevisiae
arsenate reductase
. 275:21149-21157.
2000
Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion
. 275:16420-16427.
2000
The acidic triad conserved in type IA DNA topoisomerases is required for binding of Mg(II) and subsequent conformational change
. 275:5318-5322.
2000
The ATP hydrolytic activity of purified ZntA, a Pb(II)/Cd(II)/Zn(II)-translocating ATPase from
Escherichia coli
. 275:3873-3878.
2000
Reactivity of glutaredoxins 1, 2, and 3 from
Escherichia coli
shows that glutaredoxin 2 is the primary hydrogen donor to ArsC-catalyzed arsenate reduction
. 274:36039-36042.
1999
The ATPase mechanism of ArsA, the catalytic subunit of the arsenite pump
. 274:16153-16161.
1999
Asp(45) is a Mg2+ ligand in the ArsA ATPase
. 274:13854-13858.
1999
Binding of xanthine oxidase to vascular endothelium - Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling
. 274:4985-4994.
1999
Pb(II)-translocating P-type ATPases
. 273:32614-32617.
1998
Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library
. 273:26589-26595.
1998
Evidence for a symmetrical requirement for Rab5-GTP in in vitro endosome-endosome fusion
. 273:25850-25855.
1998
Growth factor-dependent phosphorylation of the actin-binding protein cortactin is mediated by the cytoplasmic tyrosine kinase FER
. 273:23542-23548.
1998
Protein kinase B/akt and Rab5 mediate Ras activation of endocytosis
. 273:19367-19370.
1998
The cyclosporin A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell surface receptors
. 273:19664-19671.
1998
Selective ligands for the μ, δ, and κ opioid receptors identified from a single mixture based tetrapeptide positional scanning combinatorial library
. 273:18848-18856.
1998
A novel mechanism-based inhibitor (6′-bromo-5′,6′-didehydro-6′-deoxy-6′-fluorohomoadenosine) that covalently modifies human placental S-adenosylhomocysteine hydrolase
. 273:18191-18197.
1998
Site-directed mutagenesis of conserved aspartates, glutamates and arginines in the active site region of
Escherichia coli
DNA topoisomerase I
. 273:8783-8789.
1998
Steric limitations in the interaction of the ATP binding domains of the ArsA ATPase
. 273:6796-6800.
1998
Ligand interactions of the ArsC arsenate reductase
. 272:21084-21089.
1997
Tryptophan fluorescence reports nucleotide-induced conformational changes in a domain of the ArsA ATPase
. 272:19731-19737.
1997
Effect of Mg(II) binding on the structure and activity of Escherichia coli DNA topoisomerase I
. 272:16206-16210.
1997
Dimerization is essential for DNA binding and repression by the ArsR metalloregulatory protein of Escherichia coli
. 272:15734-15738.
1997
Metalloregulatory properties of the ArsD repressor
. 272:14257-14262.
1997
Uncoupling of membrane ruffling and pinocytosis during Ras signal transduction
. 272:10337-10340.
1997
Alternate energy coupling of ArsB, the membrane subunit of the Ars anion-translocating ATPase
. 272:326-331.
1997
His-8 lowers the pK(a) of the essential Cys-12 residue of the ArsC arsenate reductase of plasmid R773
. 271:33256-33260.
1996
Interaction of ATP binding sites in the ArsA ATPase, the catalytic subunit of the Ars pump
. 271:25247-25252.
1996
Spatial proximity of Cys(113), Cys(172), and Cys(422) in the metalloactivation domain of the ArsA ATPase
. 271:24465-24470.
1996
Phagocytosed live Listeria monocytogenes influences rab5-regulated in vitro phagosome-endosome fusion
. 271:13834-13843.
1996
The role of arsenic thiol interactions in metalloregulation of the ars operon
. 271:9291-9297.
1996
Functionalized protein-like structures from conformationally defined synthetic combinatorial libraries
. 271:4120-4126.
1996
Identification of inhibitors of melittin using nonsupport-bound combinatorial libraries
. 271:4093-4099.
1996
The chromosomal arsR gene of Escherichia coli encodes a trans-acting metalloregulatory protein
. 271:2427-2432.
1996
ROLE OF CYSTEINYL RESIDUES IN METALLOACTIVATION OF THE OXYANION-TRANSLOCATING ARSA ATPASE
. 270:11245-11250.
1995
The role of amphipathicity in the folding, self-association and biological activity of multiple subunit small proteins
. 270:1048-1056.
1995
ATP-DEPENDENT ARSENITE TRANSPORT IN EVERTED MEMBRANE-VESICLES OF ESCHERICHIA-COLI
. 269:25442-25446.
1994
IDENTIFICATION OF A PUTATIVE METAL-BINDING SITE IN A NEW FAMILY OF METALLOREGULATORY PROTEINS
. 269:19826-19829.
1994
Synthetic compound peptide simulating antigenicity of conformation-dependent autoepitope
. 269:18529-18534.
1994
STRUCTURAL FEATURES OF THE GTP-BINDING DEFECTIVE RAB5 MUTANTS REQUIRED FOR THEIR INHIBITORY ACTIVITY ON ENDOCYTOSIS
. 269:14631-14635.
1994
CONTRIBUTION OF THE LEISHMANIA P-GLYCOPROTEIN-RELATED GENE LTPGPA TO OXYANION RESISTANCE
. 269:11980-11986.
1994
IN-VITRO ASSEMBLY OF AN ANION-STIMULATED ATPASE FROM PEPTIDE-FRAGMENTS
. 269:9698-9704.
1994
Mutations of vaccinia virus DNA topoisomerase I that stabilize the cleavage complex
. 269:573-578.
1994
METALLOREGULATED EXPRESSION OF THE ARS OPERON
. 268:52-58.
1993
CONSTRUCTION OF A CHIMERIC ARSA-ARSB PROTEIN FOR OVEREXPRESSION OF THE OXYANION-TRANSLOCATING ATPASE
. 267:25768-25775.
1992
MUTAGENESIS OF THE C-TERMINAL NUCLEOTIDE-BINDING SITE OF AN ANION-TRANSLOCATING ATPASE
. 267:19272-19277.
1992
MEMBRANE TOPOLOGY OF THE ARSB PROTEIN, THE MEMBRANE SUBUNIT OF AN ANION-TRANSLOCATING ATPASE
. 267:12570-12576.
1992
Identification of a sequence of human activated protein C (residues 390-404) essential for its anticoagulant activity
. 266:24514-24519.
1991
ZINC(II) COORDINATION IN ESCHERICHIA-COLI DNA TOPOISOMERASE-I IS REQUIRED FOR CLEAVABLE COMPLEX-FORMATION WITH DNA
. 266:14317-14320.
1991
SUBSTRATE-INDUCED DIMERIZATION OF THE ARSA PROTEIN, THE CATALYTIC COMPONENT OF AN ANION-TRANSLOCATING ATPASE
. 266:2327-2332.
1991
Identification of a site in the α chain of platelet glycoprotein Ib that participates in von Willebrand factor binding
. 265:274-280.
1990
Structure of the von Willebrand factor domain interacting with glycoprotein Ib
. 263:17901-17904.
1988
An immunogenic region within residues Val
1670
-Glu
1684
of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor
. 263:5230-5234.
1988
Generation and characterization of peptide-specific antibodies that inhibit Von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro
1743
and other amino acid residues adjacent to the sequence Arg
1744
-Gly
1
7
. 263:7500-7505.
1988
Localization of the binding site for a factor VIII activity neutralizing antibody to amino acid residues Asp
1663
-Ser
1669
. 263:10198-10203.
1988
Temporary decrease in renal quinone reductase activity induced by chronic administration of estradiol to male Syrian hamsters. Increased superoxide formation by redox cycling of estrogen
. 263:3646-3651.
1988
Bacterial luciferase subunits are synthesized in equal quantities
. 252:803-805.
1977
CALCIUM-TRANSPORT DRIVEN BY A PROTON GRADIENT IN INVERTED MEMBRANE-VESICLES OF ESCHERICHIA-COLI
. 251:962-967.
1976
CHARACTERIZATION OF AN ACTIVE-TRANSPORT SYSTEM FOR CALCIUM IN INVERTED MEMBRANE-VESICLES OF ESCHERICHIA-COLI
. 250:7687-7692.
1975
ENERGY TRANSDUCTION IN ESCHERICHIA-COLI - ROLE OF MG2+ATPASE
. 250:8409-8415.
1975
BASIC AMINO ACID TRANSPORT IN ESCHERICHIA-COLI
. 246:3653-+.
1971
PURIFICATION AND CHARACTERIZATION OF A HISTIDINE-BINDING PROTEIN FROM SALMONELLA-TYPHIMURIUM LT-2 AND ITS RELATIONSHIP TO HISTIDINE PERMEASE SYSTEM
. 246:5351-+.
1971
Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly
. 296.
RAB5, AN EARLY ACTING ENDOSOMAL GTPASE, SUPPORTS IN-VITRO ENDOSOME FUSION WITHOUT GTP HYDROLYSIS
1994
AN ENGINEERED MUTANT OF VACCINIA VIRUS-DNA TOPOISOMERASE-I IS SENSITIVE TO THE ANTICANCER DRUG CAMPTOTHECIN
1992
Protamines, in the footsteps of linker histone evolution
2006
Escherichia coli
soft metal ion-translocating ATPases
2000
PSI relieves the pressure of membrane fusion
2020
Erratum: Structure-function analysis of the reactive site in the first Kunitz-type domain of human tissue factor pathway inhibitor-2 (Journal of Biological Chemistry (2004) 279 (17500-17507))
2004
Structure-function analysis of the reactive site in the first Kunitz-type domain of human tissue factor pathway inhibitor-2 (vol 279, pg 17500, 2004)
2004
Research
category
BIOCHEMISTRY & MOLECULAR BIOLOGY
Category
Identifiers
International Standard Serial Number (ISSN)
0021-9258
Electronic International Standard Serial Number (EISSN)
1083-351X
Other
journal abbreviation
J BIOL CHEM