Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery Article

Hamashin, C, Spindler, L, Russell, S et al. (2003). Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery . BIOORGANIC & MEDICINAL CHEMISTRY, 11(23), 4991-4997. 10.1016/j.bmc.2003.09.002

cited authors

  • Hamashin, C; Spindler, L; Russell, S; Schink, A; Lambkin, I; O'Mahony, D; Houghten, R; Pinilla, C

abstract

  • Lectin mimetics have been identified that may have potential application towards targeted drug delivery. Synthetic multivalent polygalloyl constructs effectively competed with Ulex europaeus agglutinin I (UEA1) for binding to intestinal Caco-2 cell membranes. © 2003 Elsevier Ltd. All rights reserved.

publication date

  • November 17, 2003

published in

Digital Object Identifier (DOI)

start page

  • 4991

end page

  • 4997

volume

  • 11

issue

  • 23