Deoraj, Alok Graduate Faculty
- Teaching Professor, Environmental Health Sciences , Robert Stempel College of Public Health and Social Work
Overview
overview
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Dr. Alok Deoraj is a Teaching Professor and the Graduate Program Director in the Department of Environmental Health Sciences at Florida International University in Miami, FL, USA. He teaches public health courses focused on Global Health, Environmental Health, and One Health. Additionally, Dr. Deoraj develops public health-related courses and curricula, including online degree programs.
His current research interests focus on molecular toxicology, specifically assessing the cancer risk associated with individual or combined exposures to environmental endocrine-disrupting chemicals, heavy metals, PFAS (per- and polyfluoroalkyl substances), and microplastics. Dr. Deoraj has numerous publications in his research interest areas, and he also serves as a reviewer and academic editor of professional journals.
Dr. Deoraj completed his Master of Science in Zoology at Patna University in Patna, India, and he earned his PhD in Immunology-Zoology at the National Institute of Immunology, Jawaharlal Nehru University, New Delhi, India.
Publications
selected scholarly works & creative activities
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Article
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2025RNA-Seq Uncovers Association of Endocrine-Disrupting Chemicals with Hub Genes and Transcription Factors in Aggressive Prostate Cancer. International Journal of Molecular Sciences. 26.Full Text via DOI: 10.3390/ijms26125463 Web of Science: 001516431200001
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2025Mercury Contamination and Co-exposures in the Amazon Basin: At the Center of the Planetary Environmental Crisis. Annals of Global Health. 91:1-13.Full Text via DOI: 10.5334/aogh.4817 Web of Science: 001540782400002
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2024Inhibitor of DNA Binding Protein 3 (ID3) and Nuclear Respiratory Factor 1 (NRF1) Mediated Transcriptional Gene Signatures are Associated with the Severity of Cerebral Amyloid Angiopathy. Molecular Neurobiology. 61:835-882.Full Text via DOI: 10.1007/s12035-023-03541-2 Web of Science: 001062744100002
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2023Endocrine Disrupting Chemicals Influence Hub Genes Associated with Aggressive Prostate Cancer. International Journal of Molecular Sciences. 24.Full Text via DOI: 10.3390/ijms24043191 Web of Science: 000939034100001
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2022Brain infiltration of breast cancer stem cells is facilitated by paracrine signaling by inhibitor of differentiation 3 to nuclear respiratory factor 1. Journal of Cancer Research and Clinical Oncology. 148:2881-2891.Full Text via DOI: 10.1007/s00432-022-04026-w Web of Science: 000808418200001
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2022Nuclear respiratory factor 1 transcriptomic signatures as prognostic indicators of recurring aggressive mesenchymal glioblastoma and resistance to therapy in White American females. Journal of Cancer Research and Clinical Oncology. 148:1641-1682.Full Text via DOI: 10.1007/s00432-022-03987-2 Web of Science: 000784837600002
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2022Abstract 1442: Discovery of recurrence and prognosis associated genes in prostate cancer. Cancer Research. 82:1442-1442.Full Text via DOI: 10.1158/1538-7445.am2022-1442
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2022Environmental Phenol and Paraben Exposure Risks and Their Potential Influence on the Gene Expression Involved in the Prognosis of Prostate Cancer. International Journal of Molecular Sciences. 23.Full Text via DOI: 10.3390/ijms23073679 Web of Science: 000781204300001
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2017Environmental estrogen-like endocrine disrupting chemicals and breast cancer. Molecular and Cellular Endocrinology. 457:89-102.Full Text via DOI: 10.1016/j.mce.2016.10.003 Web of Science: 000413128000011
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2016Assessing plant growth, water quality and economic effects from application of a plant-based aquafeed in a recirculating aquaponic system. Aquaculture International. 24:415-427.Full Text via DOI: 10.1007/s10499-015-9934-3 Web of Science: 000372553000030
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2016Association between Exposure to Estrogenic Endocrine Disruptors - Polychlorinated Biphenyls, Phthalates, and Bisphenol A and Gynecologic Cancers- Cervical, Ovarian, Uterine Cancers. Journal of Carcinogenesis & Mutagenesis. 07:1-14.Full Text via DOI: 10.4172/2157-2518.1000275
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2015Integrated Bioinformatics, Environmental Epidemiologic and Genomic Approaches to Identify Environmental and Molecular Links between Endometriosis and Breast Cancer. International Journal of Molecular Sciences. 16:25285-25322.Full Text via DOI: 10.3390/ijms161025285 Web of Science: 000364232100114
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2015Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells. British Journal of Cancer. 112:1687-1702.Full Text via DOI: 10.1038/bjc.2014.586 Web of Science: 000354376500009
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2003Effects of controlled delivery and acute injections of LHRHa on bullseye puffer fish (Sphoeroides annulatus) spawning. Aquaculture. 218:625-635.Full Text via DOI: 10.1016/S0044-8486(02)00299-5 Web of Science: 000181376100050
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2001Recombinant perciform GnRH-R activates different signaling pathways in fish and mammalian heterologous cell lines. Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 129:375-380.Full Text via DOI: 10.1016/S1096-4959(01)00325-6 Web of Science: 000169374800021
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2000Characterization of a pituitary GnRH-receptor from a perciform fish, Morone saxatilis: functional expression in a fish cell line. Molecular and Cellular Endocrinology. 168:65-75.Full Text via DOI: 10.1016/S0303-7207(00)00317-8 Web of Science: 000165062000007
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2000Cloning and functional expression of a thyrotropin receptor from the gonads of a vertebrate (bony fish): potential thyroid-independent role for thyrotropin in reproduction. Molecular and Cellular Endocrinology. 167:1-9.Full Text via DOI: 10.1016/S0303-7207(00)00304-X Web of Science: 000089571600001
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2000In vivo activity of salmon gonadotropin releasing hormone (GnRH), its agonists with structural modifications at positions 6 and 9, mammalian GnRH agonists and native cGnRH-II on the spawning of an Indian catfish. Aquaculture International. 7:383-392.Full Text via DOI: 10.1023/A:1009262230465 Web of Science: 000085704500002
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1998Multiple GnRHs present in a teleost species are encoded by separate genes: analysis of the sbGnRH and cGnRH-II genes from the striped bass, Morone saxatilis. Journal of Molecular Endocrinology. 21:277-289.Full Text via DOI: 10.1677/jme.0.0210277 Web of Science: 000077920600004
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1998GnRH analog stimulates gonadotropin II gene expression in maturing sockeye salmon. Zoological Science. 15:761-765.Full Text via DOI: 10.2108/zsj.15.761 Web of Science: 000077864200021
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1998Gonadotropin-releasing hormone analog and sex steroids shorten homing duration of sockeye salmon in Lake Shikotsu. Zoological Science. 15:767-771.Full Text via DOI: 10.2108/zsj.15.767 Web of Science: 000077864200022
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1998Multiple induced spawnings of the Indian catfish Heteropneustes fossilis (Bloch) within a prolonged spawning season. Journal of the World Aquaculture Society. 29:252-258.Full Text via DOI: 10.1111/j.1749-7345.1998.tb00985.x Web of Science: 000074324100014
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1997Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: Up-regulation of poly(A) polymerase. Proceedings of the National Academy of Sciences of the United States of America. 94:12598-12603.Full Text via DOI: 10.1073/pnas.94.23.12598 Web of Science: A1997YF39300064
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1997Effect of D-Lys(6) salmon sGnRH alone and in combination with domperidone on the spawning of common carp during the late spawning season. Aquaculture International. 5:369-374.Full Text via DOI: 10.1023/A:1018320325162 Web of Science: A1997XK86800008
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1996Translational fusion of heat labile enterotoxin chain B and beta-subunit of human chorionic gonadotropin: Periplasmic expression in Escherichia coli and its immunogenicity. FEBS Letters. 387:23-26.Full Text via DOI: 10.1016/0014-5793(96)00428-0 Web of Science: A1996UP83800005
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1994PRECOCIOUS OVARIAN RECRUDESCENCE AND INDUCED OFF-SEASON SPAWNING OF HETEROPNEUSTES-FOSSILIS BY D-LYS6 SALMON GONADOTROPIN-RELEASING-HORMONE ANALOG (SGNRH-A). Journal of Fish Biology. 45:909-915.Web of Science: A1994PY01000001
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1993INDUCED SPAWNING OF CATFISH, HETEROPNEUSTES-FOSSILIS (BLOCH), USING D-LYS(6) SALMON GONADOTROPIN-RELEASING-HORMONE ANALOG. Aquaculture. 115:159-167.Full Text via DOI: 10.1016/0044-8486(93)90366-7 Web of Science: A1993LU21900014
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1989Gene transfer in fish embryos for increased productivity. Theriogenology. 31:167.Full Text via DOI: 10.1016/0093-691X(89)90575-X
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Book Chapter
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2010Approaches to Identify Environmental and Epigenomic Components or Covariates of Cancer and Disease Susceptibility. 197-219.Full Text via DOI: 10.1007/978-1-4419-6752-7_8 Web of Science: 000282535900008
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Conference
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2022A NRF1-driven JRK-mediated β-catenin transcriptional activity contributes to the aggressive growth of ovarian cancer. Cancer Research.Web of Science: 000892509506088
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2018Exosomal ID3 is pro-metastatic through guiding NRF1-induced breast cancer stem cells across the blood-brain-barrier. Cancer Research.Full Text via DOI: 10.1158/1538-7445.AM2018-1128 Web of Science: 000468818903101
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2015Phosphodeficient NRF1 mutant suppresses the susceptibility of the breast epithelial cells to develop tumors when exposed to estrogen - a major breast cancer risk factor. Cancer Research.Full Text via DOI: 10.1158/1538-7445.AM2015-4559 Web of Science: 000371597104187
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Other Scholarly Work
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2023Checkpoint Kinase I, Cyclin E1, and Exonuclease I genes play role in the survival of lung adenocarcinoma patients. Cancer Research.Full Text via DOI: 10.1158/1538-7445.AM2023-3158 Web of Science: 001008499100135
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2023ID3 controlled dynamic Pyk2 localization is important for the mobility of cancer stem cells. Cancer Research.Full Text via DOI: 10.1158/1538-7445.AM2023-1278 Web of Science: 001008193602212
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2016Association between serum concentrations of polychlorinated biphenyls (PCBs) and increased risk of breast cancer among US women. Cancer Research.Full Text via DOI: 10.1158/1538-7445.AM2016-3433 Web of Science: 000389940604187
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2010Differential role of estrogen receptor positive NRF1(High) and NRF1(Low) cells in breast cancer development and progression. New Biotechnology. S25-S25.Full Text via DOI: 10.1016/j.nbt.2010.01.021 Web of Science: 000209825000061
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Preprint
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Review
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2020The gut microbiome and neuropsychiatric disorders: implications for attention deficit hyperactivity disorder (ADHD). Journal of Medical Microbiology. 14-24.Full Text via DOI: 10.1099/jmm.0.001112 Web of Science: 000518384100003
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2011Estrogen-induced reactive oxygen species-mediated signalings contribute to breast cancer. Biochimica et Biophysica Acta - Reviews on Cancer. 115-133.Full Text via DOI: 10.1016/j.bbcan.2010.10.005 Web of Science: 000287124400009
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Contact
full name
- Alok Deoraj
