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Bhattarai, Nisha
Positions
Postdoctoral Associate
,
Physics
,
College of Arts, Sciences & Education
nbhattar@fiu.edu
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Scholarly & Creative Works
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Scholarly & Creative Works
selected scholarly works & creative activities
Article
2024
Ebola Virus Matrix Protein VP40 Single Mutations G198R and G201R Significantly Enhance Plasma Membrane Localization
.
JOURNAL OF PHYSICAL CHEMISTRY B
.
Full Text via DOI:
10.1021/acs.jpcb.4c02700
Web of Science:
001324894400001
2024
A Computational Approach in the Systematic Search of the Interaction Partners of Alternatively Spliced TREM2 Isoforms.
.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
. 25:9667.
Full Text via DOI:
10.3390/ijms25179667
2024
PI(4,5)P2 binding sites in the Ebola virus matrix protein VP40 modulate assembly and budding
.
JOURNAL OF LIPID RESEARCH
. 65.
Full Text via DOI:
10.1016/j.jlr.2024.100512
Web of Science:
001199138100001
2024
Impact of the AQP5 H173D mutation on H2O and CO2 permeability: Physiology and MD studies
.
BIOPHYSICAL JOURNAL
. 123:265a-266a.
Full Text via DOI:
10.1016/j.bpj.2023.11.1663
2024
Molecular dynamics simulations reveal molecular mechanisms for the gain and loss of function effects of four SCN2A variants
.
BIOPHYSICAL JOURNAL
. 123:109a-110a.
Full Text via DOI:
10.1016/j.bpj.2023.11.779
2022
Detecting Individual Proteins and Their Surface Charge Variations in Solution by the Potentiometric Nanoimpact Method
.
ACS SENSORS
. 7:555-563.
Full Text via DOI:
10.1021/acssensors.1c02385
Web of Science:
000746813600001
2022
Ebola virus protein VP40 binding to Sec24c for transport to the plasma membrane
.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
. 90:340-350.
Full Text via DOI:
10.1002/prot.26221
Web of Science:
000692659700001
2022
Lipid II Binding and Transmembrane Properties of Various Antimicrobial Lanthipeptides
.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
. 18:516-525.
Full Text via DOI:
10.1021/acs.jctc.1c00666
Web of Science:
000730568600001
2021
Mutation-induced changes in the receptor-binding interface of the SARS-CoV-2 Delta variant B.1.617.2 and implications for immune evasion
.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
. 574:14-19.
Full Text via DOI:
10.1016/j.bbrc.2021.08.036
Web of Science:
000687461600001
2021
Structural and Dynamical Differences in the Spike Protein RBD in the SARS-CoV-2 Variants B.1.1.7 and B.1.351
.
JOURNAL OF PHYSICAL CHEMISTRY B
. 125:7101-7107.
Full Text via DOI:
10.1021/acs.jpcb.1c01626
Web of Science:
000672740600004
2021
Cysteine Mutations in the Ebolavirus Matrix Protein VP40 Promote Phosphatidylserine Binding by Increasing the Flexibility of a Lipid-Binding Loop
Full Text via DOI:
10.3390/v13071375
Web of Science:
000677080900001
2020
EF-hands in Neuronal Calcium Sensor Downstream Regulatory Element Antagonist Modulator Demonstrate Submillimolar Affinity for Li+: A New Prospect for Li+ Therapy
.
ACS CHEMICAL NEUROSCIENCE
. 11:2543-2548.
Full Text via DOI:
10.1021/acschemneuro.0c00399
Web of Science:
000569269100010
2020
Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane
Full Text via DOI:
10.3390/v12040482
Web of Science:
000539525300124
2019
Conformational Flexibility of the Protein-Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament
.
JOURNAL OF PHYSICAL CHEMISTRY B
. 123:9045-9053.
Full Text via DOI:
10.1021/acs.jpcb.9b04674
Web of Science:
000493865200001
2019
Molecular mechanisms of pore formation and membrane disruption by the antimicrobial lantibiotic peptide Mutacin 1140
.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
. 21:12530-12539.
Full Text via DOI:
10.1039/c9cp01558b
Web of Science:
000478994100046
2018
Role of K-Loop Cysteine Residues in the Marburg Virus Protein VP24-Human Keap1 Complex
.
ACS OMEGA
. 3:18639-18645.
Full Text via DOI:
10.1021/acsomega.8b02386
Web of Science:
000458439900046
2017
Graphene-VP40 interactions and potential disruption of the Ebola virus matrix filaments
.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
. 493:176-181.
Full Text via DOI:
10.1016/j.bbrc.2017.09.052
Web of Science:
000413134200028
2017
Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry
Full Text via DOI:
10.1074/jbc.M116.758300
Web of Science:
000399538700009
2017
Plasma membrane association facilitates conformational changes in the Marburg virus protein VP40 dimer
.
RSC ADVANCES
. 7:22741-22748.
Full Text via DOI:
10.1039/c7ra02940c
Web of Science:
000400338000016
Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly
.
JOURNAL OF BIOLOGICAL CHEMISTRY
. 296.
Full Text via DOI:
10.1016/j.jbc.2021.100796
Web of Science:
000674717300016
Conference
2020
Computational Study of the Molecular Details of Ebola Virus Matrix Protein VP40 and Human Sec24C Protein Interaction
.
BIOPHYSICAL JOURNAL
. 506A-506A.
Web of Science:
000513023203272
2019
Dynamics of the Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament
.
BIOPHYSICAL JOURNAL
. 472A-472A.
Full Text via DOI:
10.1016/j.bpj.2018.11.2549
Web of Science:
000460779802370
2019
Molecular Basis of the Marburg Virus Protein VP24 Interactions with Human Keap1
.
BIOPHYSICAL JOURNAL
. 182A-182A.
Full Text via DOI:
10.1016/j.bpj.2018.11.1011
Web of Science:
000460779800901
2019
Molecular Dynamics Investigations of Enzyme Conformational Changes
.
BIOPHYSICAL JOURNAL
. 186A-186A.
Full Text via DOI:
10.1016/j.bpj.2018.11.1031
Web of Science:
000460779800921
2018
Conformational Changes in Marburg Virus VP40 upon Plasma Membrane Association
.
BIOPHYSICAL JOURNAL
. 459A-459A.
Web of Science:
000430563200066
2017
Plasma membrane localization dynamics of the filovirus matrix protein VP40
.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
. S211-S211.
Web of Science:
000416406201256
Other Scholarly Work
2022
Changes in the receptor-binding interface may cause immune evasion by the SARS-CoV-2 delta variant b.1.617.2
.
BIOPHYSICAL JOURNAL
. 44-44.
Web of Science:
000759523000209
2021
Effects of G198R Mutation in the Ebola VP40 Matrix Protein: A Molecular Dynamics Study
.
BIOPHYSICAL JOURNAL
. 303A-303A.
Web of Science:
000629601401715
2018
Potential Disruption of Ebola Virus Matrix by Graphene Nano-Sheets
.
BIOPHYSICAL JOURNAL
. 218A-218A.
Full Text via DOI:
10.1016/j.bpj.2017.11.1217
Web of Science:
000430439600337
Preprint
2024
Distances from ligands as main predictive features for pathogenicity and functional effect of variants in NMDA receptors.
Full Text via DOI:
10.1101/2024.05.06.24306939
2023
The role of protonation in the PfMATE transporter protein structural transitions
Full Text via DOI:
10.22541/au.169645521.18264971/v1
2021
Mutation-induced Changes in the Receptor-binding Interface of the SARS-CoV-2 Delta Variant B.1.617.2 and Implications for Immune Evasion
Full Text via DOI:
10.1101/2021.07.17.452576
2020
Lipid-specific protein oligomerization is regulated by two interfaces in Marburg virus matrix protein VP40
Full Text via DOI:
10.1101/2020.11.13.381350
2020
Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane
Full Text via DOI:
10.20944/preprints202002.0467.v1
2018
Mutation of Ebola Virus Matrix Protein Cysteine Residues Increases Binding to Phosphatidylserine through Increased Flexibility of a Lipid Binding Loop
Full Text via DOI:
10.1101/286120
2018
PI(4,5)P
2
Binding Sites in the Ebola Virus Matrix Protein Modulate Assembly and Budding
Full Text via DOI:
10.1101/341248
Molecular dynamics simulations reveal molecular mechanisms for the gain and loss of function effects of four SCN2A variants
Full Text via DOI:
10.1101/2024.02.19.580930
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full name
Nisha
Bhattarai
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ORCID iD
https://orcid.org/0000-0002-5595-1474
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