Computational model predicts function of Rho-GTPase binding for plexin receptor GAP activity on Rap1b via dynamic allosteric changes Article

Bhattarai, Nisha, Morrison, Lindsay, Gomes, Alexandre F et al. (2025). Computational model predicts function of Rho-GTPase binding for plexin receptor GAP activity on Rap1b via dynamic allosteric changes . PROTEIN SCIENCE, 34(7), 10.1002/pro.70196

Open Access Industry Collaboration

cited authors

  • Bhattarai, Nisha; Morrison, Lindsay; Gomes, Alexandre F; Savage, Paul; Sahoo, Amita R; Buck, Matthias

sustainable development goals

authors

publication date

  • July 1, 2025

published in

keywords

  • ACTIVATING PROTEIN
  • Biochemistry & Molecular Biology
  • DOMAIN
  • FAMILY
  • GTPases
  • Life Sciences & Biomedicine
  • MUTATIONS
  • RAC
  • RELAXATION
  • RND1
  • SEMAPHORINS
  • Science & Technology
  • dynamic allostery
  • hydrogen-deuterium exchange
  • molecular dynamics simulations
  • plexin transmembrane receptor
  • protein-protein interactions

Digital Object Identifier (DOI)

publisher

  • WILEY

volume

  • 34

issue

  • 7