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Computation model predicts Rho GTPase function with the Plexin Transmembrane receptor GAP activity on Rap1b via dynamic allosteric changes.
Preprint
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cited authors
Bhattarai, Nisha; Morrison, Lindsay; Gomes, Alexandre F; Savage, Paul; Sahoo, Amita R; Buck, Matthias
authors
Bhattarai, Nisha
publication date
May 14, 2025
webpage
https://www.ncbi.nlm.nih.gov/pubmed/40462934
Research
keywords
GTPases
Molecular dynamics simulations
Plexins
Structural biology
hydrogen-deuterium
mass spectroscopy
Identifiers
Digital Object Identifier (DOI)
https://doi.org/10.1101/2025.03.13.643120