Growing Up: Intervening with HIV positive adolescents in resource-poor settings Grant

abstract

  • ApediatriHIinfectiohashiftefrobeinfatadiseastchroniillnessgrowincohoroyounpeoplarmovinthrougadolescencwitalthchallengeothadulHIV-infectepopulatiobulargelwithoucomparabltreatmenoutcomeoaevidencbastimprovadherenctantiretroviratreatmen(ARTanpreventivbehaviorDespitoveraldeclineiHIincidencanmortalitsincthARscale-upbothavriseamonyouthThgoaothpropose3-yeaR3developmentastuditrespontthineefotailoreresearchiparticulaamonHIVoldeadolescentsancontributtunderstandinthaddevaluiresource-limitesettingoincludincaregiveriaadherencanrisreductioprogramAlthougcaregiveinvolvemenirecognizecorrelatooutcomeiHIVyouththerarnrigoroustudieothrolocaregiverioutcomeamonHIVoldeadolescentsThiprojecwilintegratcaregiveinvolvemenancognitivbehaviorainterventio(CBIelementtimprovARadherencanHIrisreductiofoHIVoldeadolescenttreateiresource-pooclinicasettingsOuproposestudpopulatiowilincludcaregiveran1t1year-olHIVyoutwhknotheistatuanarreceivinARiPort-au-PrinceHaitiGuidebththeoreticaframeworothdevelopmentallsensitivInformation-Motivation-BehavioraSkillfoPediatriAdherenc(IMB-PED)wwildeveloGrowinU(N'aGrandiiHaitiaCreoleacollaborativmodeocaregiver-adolescenengagemenithkeinformationalmotivationalanbehavioraskillantecedentoARadherencanrisreductionThproposestudpartnerwitHaiti'largesyouthealtproviderFOSREFanbuildupoprioworwitHIVyoutanadultiPort-au-PrinceThstudwilutilizqualitativanquantitativmethodtoidentifbarrieranfacilitatortadherencanrisreductio(Ai1)develoanpretesN'aGrandiincludindevelopmentally-appropriatmanualstraininmaterialsproceduresanpsychometriadequacomeasure(Ai2)anassesfeasibilitanpreliminarefficaci3-arrandomizecontrolletria(RCT)iwhic12youtwilbassignetthregroupsthexperimentacaregiver-adolescenN'aGrandiaadolescent-onlversio(N'aGrandi-Aanaadolescent-onlhealtpromotiogrou(HP-A)examininARadherencanvirologiresponseHIrisbehaviorspositivcommunicatioanmonitoringstresanmoodancostfrothhealtcenteperspectiv(Ai3)IsolationinhibitecommunicationcaregivedistressadolescenARnon-adherencanHIrisarverhigiHaitiwhicimicrocosothglobapediatriHIepidemiiloanmiddlincomcountrie(LMICswitgeneralizeepidemicsAftesubSaharaAfricathCaribbeaithmosHIV-affecteregioithworldwit50opeoplwitHIinfectioliviniHaitiOuproposestudwilbthfirstailoreinterventioanRCpilotfoHIVadolescentiHaitianwilrepresenonoonlhandfuiLMICglobally.

date/time interval

  • August 25, 2015 - May 31, 2019

awarded by

administered by

sponsor award ID

  • 5R34MH107335-03

local award ID

  • AWD000000004965

contributor

keywords

  • 15 year old
  • 19 year old
  • AIDS prevention
  • AIDS/HIV problem
  • Adherence
  • Adolescence
  • Adolescent
  • Adult
  • Affect
  • Africa South of the Sahara
  • Anti-Retroviral Agents
  • Antiretroviral resistance
  • Attention
  • Back
  • Behavior
  • Behavioral
  • Caregiver
  • antiretroviral therapy
  • arm
  • base