Synthesis of 5 '-functionalized nucleosides: S-Adenosylhomocysteine analogues with the carbon-5 ' and sulfur atoms replaced by a vinyl or halovinyl unit Article

Wnuk, Stanislaw F, Sacasa, Pablo R, Lewandowska, Elzbieta et al. (2008). Synthesis of 5 '-functionalized nucleosides: S-Adenosylhomocysteine analogues with the carbon-5 ' and sulfur atoms replaced by a vinyl or halovinyl unit . BIOORGANIC & MEDICINAL CHEMISTRY, 16(10), 5424-5433. 10.1016/j.bmc.2008.04.017

Open Access

cited authors

  • Wnuk, Stanislaw F; Sacasa, Pablo R; Lewandowska, Elzbieta; Andrei, Daniela; Cai, Sumin; Borchardt, Ronald T

sustainable development goals

authors

publication date

  • May 15, 2008

published in

keywords

  • 1,1-DICHLORO-1-ALKENES
  • ACID RELATED-COMPOUNDS
  • ADENOSINE
  • ANTIVIRAL ACTIVITY
  • Biochemistry & Molecular Biology
  • Chemistry
  • Chemistry, Medicinal
  • Chemistry, Organic
  • HYDROLYTIC ACTIVITY
  • INACTIVATION
  • L-HOMOCYSTEINE HYDROLASE
  • Life Sciences & Biomedicine
  • MECHANISM-BASED INHIBITORS
  • OLEFIN METATHESIS
  • Pharmacology & Pharmacy
  • Physical Sciences
  • S-adenosylhomocysteine hydrolase
  • Science & Technology
  • URIDINE
  • cross-coupling
  • cross-metathesis
  • nucleosides
  • wittig reaction

Digital Object Identifier (DOI)

publisher

  • PERGAMON-ELSEVIER SCIENCE LTD

start page

  • 5424

end page

  • 5433

volume

  • 16

issue

  • 10