Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase Article

Musilek, K, Kuca, K, Jun, D et al. (2006). Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase . BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(3), 622-627. 10.1016/j.bmcl.2005.10.059

keywords

  • ANTIDOTAL TREATMENT
  • Chemistry
  • Chemistry, Medicinal
  • Chemistry, Organic
  • DESIGN
  • DIBROMIDE
  • LIVER
  • Life Sciences & Biomedicine
  • NERVE AGENTS
  • OXIMES
  • Pharmacology & Pharmacy
  • Physical Sciences
  • RAT-BRAIN ACETYLCHOLINESTERASE
  • Science & Technology
  • acetylcholinesterase
  • chlorpyrifos
  • organophosphate
  • oxime
  • pesticide
  • reactivation

Digital Object Identifier (DOI)

publisher

  • PERGAMON-ELSEVIER SCIENCE LTD

start page

  • 622

end page

  • 627

volume

  • 16

issue

  • 3