Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase Article

Musilek, Kamil, Holas, Ondrej, Kuca, Kamil et al. (2006). Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase . BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(21), 5673-5676. 10.1016/j.bmcl.2006.08.011

cited authors

  • Musilek, Kamil; Holas, Ondrej; Kuca, Kamil; Jun, Daniel; Dohnal, Vlastimil; Dolezal, Martin

sustainable development goals

authors

publication date

  • November 1, 2006

webpage

published in

keywords

  • AGENT
  • AMINO-ACID-RESIDUES
  • BINDING
  • CHOLINESTERASES
  • Chemistry
  • Chemistry, Medicinal
  • Chemistry, Organic
  • DESIGN
  • DIBROMIDE
  • LINKER
  • Life Sciences & Biomedicine
  • OXIMES
  • PYRIDINIUM
  • Pharmacology & Pharmacy
  • Physical Sciences
  • SERIES
  • Science & Technology
  • acetylcholinesterase
  • nerve agent
  • oxime
  • paraoxon
  • pesticide
  • reactivation
  • reactivator
  • tabun

Digital Object Identifier (DOI)

publisher

  • PERGAMON-ELSEVIER SCIENCE LTD

start page

  • 5673

end page

  • 5676

volume

  • 16

issue

  • 21