Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage - Implications for early Myasthenia gravis treatment Article

Musilek, Kamil, Komloova, Marketa, Holas, Ondrej et al. (2011). Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage - Implications for early Myasthenia gravis treatment . EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 46(2), 811-818. 10.1016/j.ejmech.2010.12.011

International Collaboration

cited authors

  • Musilek, Kamil; Komloova, Marketa; Holas, Ondrej; Hrabinova, Martina; Pohanka, Miroslav; Dohnal, Vlastimil; Nachon, Florian; Dolezal, Martin; Kuca, Kamil

sustainable development goals

authors

publication date

  • February 1, 2011

published in

keywords

  • ACETYLCHOLINESTERASE INHIBITORS
  • BINDING
  • BRAIN
  • Chemistry, Medicinal
  • Cholinesterase
  • ENTRY
  • In vitro
  • Inhibitor
  • Life Sciences & Biomedicine
  • Molecular docking
  • Myasthenia gravis
  • OXIMES
  • PYRIDOSTIGMINE
  • Pharmacology & Pharmacy
  • REACTIVATORS
  • SAR
  • SUBSTRATE
  • Science & Technology

Digital Object Identifier (DOI)

publisher

  • ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER

start page

  • 811

end page

  • 818

volume

  • 46

issue

  • 2