A high-throughput fluorescent DNA cleavage assay for discovering bacterial DNA gyrase poisons Article

Dias, Matthew, Annamalai, Thirunavukkarasu, Otsuka, Yuka et al. (2026). A high-throughput fluorescent DNA cleavage assay for discovering bacterial DNA gyrase poisons . NUCLEIC ACIDS RESEARCH, 54(11), 10.1093/nar/gkag610

cited authors

  • Dias, Matthew; Annamalai, Thirunavukkarasu; Otsuka, Yuka; Leng, Sophia; Chapagain, Trisha; Ferdous, Shomita; Shumate, Justin; Scampavia, Louis; Spicer, Timothy P; Leng, Fenfei

authors

publication date

  • June 24, 2026

published in

keywords

  • ATPASE
  • Biochemistry & Molecular Biology
  • DEOXYRIBONUCLEIC-ACID
  • DRUGS
  • FLUOROQUINOLONE
  • IIA TOPOISOMERASE
  • INHIBITORS
  • Life Sciences & Biomedicine
  • QUINOLONE ACTION
  • RESISTANCE
  • RISK
  • STRAND BREAKAGE
  • Science & Technology

Digital Object Identifier (DOI)

publisher

  • OXFORD UNIV PRESS

volume

  • 54

issue

  • 11