Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs Article

McGivney, Gavin R, Brockman, Qierra R, Borcherding, Nicholas et al. (2025). Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs . 11(33), 10.1126/sciadv.adu2906

Open Access International Collaboration

cited authors

  • McGivney, Gavin R; Brockman, Qierra R; Borcherding, Nicholas; Scherer, Amanda; Rauckhorst, Adam J; Gutierrez, Wade R; Solst, Shane R; Heer, Collin D; Warrier, Akshaya; Floyd, Warren; Kirsch, David G; Knepper-Adrian, Vickie L; Laverty, Emily A; Roughton, Grace A; Spitz, Douglas R; Taylor, Eric B; Dodd, Rebecca D

sustainable development goals

authors

publication date

  • August 13, 2025

keywords

  • ARF
  • BREAST
  • CANCER GENOMICS
  • DUAL ROLES
  • LUNG-CANCER
  • Multidisciplinary Sciences
  • NRF2
  • STRESS
  • Science & Technology
  • Science & Technology - Other Topics

Digital Object Identifier (DOI)

publisher

  • AMER ASSOC ADVANCEMENT SCIENCE

volume

  • 11

issue

  • 33