Libraries from libraries: A series of sulfonamide linked heterocycles derived from the same scaffold Article

Debevec, G, Chen, W, Yu, Y et al. (2013). Libraries from libraries: A series of sulfonamide linked heterocycles derived from the same scaffold . TETRAHEDRON LETTERS, 54(32), 4296-4299. 10.1016/j.tetlet.2013.06.003

cited authors

  • Debevec, G; Chen, W; Yu, Y; Houghten, RA; Giulianotti, MA

abstract

  • A libraries from libraries approach is described for the synthesis of five different sulfonamide linked scaffolds. Four of the scaffolds are sulfonamides linked to heterocycles; piperazine, thiourea, cyclic guanidine, and dimethyl cyclic guanidine. The fifth scaffold is a polyamine linked sulfonamide. Three different diversity positions were effectively incorporated into each scaffold providing a number of different compounds with good yields and purity. © 2013 Elsevier Ltd. All rights reserved.

publication date

  • August 7, 2013

published in

Digital Object Identifier (DOI)

start page

  • 4296

end page

  • 4299

volume

  • 54

issue

  • 32