Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: An example of lead optimization using mixture-based libraries Article

Nefzi, Adel, Ostresh, John M, Appel, Jon R et al. (2006). Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: An example of lead optimization using mixture-based libraries . BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(16), 4331-4338. 10.1016/j.bmcl.2006.05.053

cited authors

  • Nefzi, Adel; Ostresh, John M; Appel, Jon R; Bidlack, Jean; Dooley, Colette T; Houghten, Richard A

sustainable development goals

authors

publication date

  • August 15, 2006

webpage

published in

keywords

  • CHEMISTRY
  • Chemistry
  • Chemistry, Medicinal
  • Chemistry, Organic
  • DRUG DISCOVERY
  • GUANIDINES
  • Life Sciences & Biomedicine
  • PEPTIDE COMBINATORIAL LIBRARIES
  • PEPTIDOMIMETICS
  • Pharmacology & Pharmacy
  • Physical Sciences
  • RAPID IDENTIFICATION
  • SOLID-PHASE SYNTHESIS
  • Science & Technology
  • TRANSFORMATION
  • amide reduction
  • libraries
  • mu opiate receptors
  • polyamines
  • positional scanning libraries

Digital Object Identifier (DOI)

publisher

  • PERGAMON-ELSEVIER SCIENCE LTD

start page

  • 4331

end page

  • 4338

volume

  • 16

issue

  • 16