Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734 821 Pyrrolidine Bis-piperazines Article

Houghten, Richard A, Ganno, Michelle L, McLaughlin, Jay P et al. (2016). Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734 821 Pyrrolidine Bis-piperazines . 18(1), 51-64. 10.1021/acscombsci.5b00126

Open Access

cited authors

  • Houghten, Richard A; Ganno, Michelle L; McLaughlin, Jay P; Dooley, Colette T; Eans, Shainnel O; Santos, Radleigh G; LaVoi, Travis; Nefzi, Adel; Welmaker, Greg; Giulianotti, Marc A; Toll, Lawrence

sustainable development goals

publication date

  • January 1, 2016

keywords

  • BASIC RESEARCH
  • Chemistry
  • Chemistry, Applied
  • Chemistry, Medicinal
  • Chemistry, Multidisciplinary
  • DECONVOLUTION
  • DISCOVERY
  • IN-VIVO
  • Life Sciences & Biomedicine
  • PEPTIDE
  • POTENT
  • Pharmacology & Pharmacy
  • Physical Sciences
  • SCAFFOLD RANKING
  • SYNTHETIC COMBINATORIAL LIBRARIES
  • Science & Technology
  • TETRAPEPTIDE
  • TRAMADOL
  • analgesia
  • in vivo high-throughput screening
  • mixture-based combinatorial libraries
  • opioid

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 51

end page

  • 64

volume

  • 18

issue

  • 1