FIU Discovery

Novel role for the Golgi membrane protein TMEM165 in control of migration and invasion for breast carcinoma

Generation of a Fully Human scFv that binds Tumor-Specific Glycoforms

Methyl helicterte ameliorates liver fibrosis by regulating miR-21-mediated ERK and TGF-β1/Smads pathways.  INTERNATIONAL IMMUNOPHARMACOLOGY.  66:41-51.

CSIG-01. GLYCOPHOSPHATIDYLINOSITOL TRANSAMIDASE (GPIT) SUBUNIT GPAA1 IS OVEREXPRESSED IN GLIOBLASTOMA MULTIFORME (GBM) CELL LINES AND CONTRIBUTES TO TUMOR CELL MIGRATION.  NEURO-ONCOLOGY.  20:vi43-vi43.

Inhibition of RKIP aggravates thioacetamide-induced acute liver failure in mice.  EXPERIMENTAL AND THERAPEUTIC MEDICINE.  16:2992-2998.

Gypsophila elegans isoorientin-2″-O-α-L-arabinopyranosyl ameliorates porcine serum-induced immune liver fibrosis by inhibiting NF-κB signaling pathway and suppressing HSC activation.  INTERNATIONAL IMMUNOPHARMACOLOGY.  54:60-67.

Trolline Ameliorates Liver Fibrosis by Inhibiting the NF-κB Pathway, Promoting HSC Apoptosis and Suppressing Autophagy.  CELLULAR PHYSIOLOGY AND BIOCHEMISTRY.  44:436-446.

The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.  JOURNAL OF BIOLOGICAL CHEMISTRY.  292:16351-16359.

Didymin induces apoptosis through mitochondrial dysfunction and up-regulation of RKIP in human hepatoma cells

Didymin Alleviates Hepatic Fibrosis Through Inhibiting ERK and PI3K/Akt Pathways via Regulation of Raf Kinase Inhibitor Protein.  CELLULAR PHYSIOLOGY AND BIOCHEMISTRY.  40:1422-1432.

Raf Kinase Inhibitory Protein Down-Expression Exacerbates Hepatic Fibrosis in Vivo and in Vitro.  CELLULAR PHYSIOLOGY AND BIOCHEMISTRY.  40:49-61.

Isoorientin from Gypsophila elegans induces apoptosis in liver cancer cells via mitochondrial-mediated pathway.  JOURNAL OF ETHNOPHARMACOLOGY.  187:187-194.

Loss of Raf kinase inhibitor protein is associated with malignant progression in hepatic fibrosis

Gypsophila elegans isoorientin attenuates CCl4-induced hepatic fibrosis in rats via modulation of NF-κB and TGF-β1/Smad signaling pathways.  INTERNATIONAL IMMUNOPHARMACOLOGY.  28:305-312.

Pratensein ameliorates β-amyloid-induced cognitive impairment in rats via reducing oxidative damage and restoring synapse and BDNF levels

Pratensein attenuates Aβ-induced cognitive deficits in rats: Enhancement of synaptic plasticity and cholinergic function

Protective effect of madecassoside against cognitive impairment induced by d-galactose in mice.  PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR.  124:434-442.

Glycomic changes of the notch 1 receptor in ovarian Cancer affect the cancer stem cell growth.  GLYCOBIOLOGY. 1766-1766.

Novel method for glycan-targeted scFvC9 chimeras to mediate receptor degradation in ovarian Cancer.  GLYCOBIOLOGY. 1765-1766.

Corrigendum to “Pratensein attenuates Aβ-induced cognitive deficits in rats: Enhancement of synaptic plasticity and cholinergic function” [Fitoterapia 101 (2015) 208–217] (Fitoterapia (2015) 101 (208–217), (S0367326X15000283), (10.1016/j.fitote.2015.01.017))

Corrigendum to “Didymin induces apoptosis through mitochondrial dysfunction and up-regulation of RKIP in human hepatoma cells” [Chem. Biol. Interact. 261 (2017) 118-126] (Chemico-Biological Interactions (2017) 261(118-126) (S0009279716306470), (10.1016/j.cbi.2016.11.026))

Corrigendum to “Protective effect of madecassoside against cognitive impairment induced by D-galactose in mice” [Pharmacol. Biochem. Behav. 124 (2014) 434–442](S0091305714002184)(10.1016/j.pbb.2014.07.014).  PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR.

Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.  77-87.

Corrigendum to “Methyl helicterte ameliorates liver fibrosis by regulating miR-21-mediated ERK and TGF-β1/Smads pathways”. (International Immunopharmacology (2019) 66 (41–51), (S1567576918304521), (10.1016/j.intimp.2018.11.006)).  INTERNATIONAL IMMUNOPHARMACOLOGY.

Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation

Methyl helicterate inhibits hepatic stellate cell activation through downregulating the ERK1/2 signaling pathway.  JOURNAL OF CELLULAR BIOCHEMISTRY. 14936-14945.

Role of RKIP in human hepatic stellate cell proliferation, invasion, and metastasis.  JOURNAL OF CELLULAR BIOCHEMISTRY. 6168-6177.

Helenalin attenuates alcohol-induced hepatic fibrosis by enhancing ethanol metabolism, inhibiting oxidative stress and suppressing HSC activation.  203-213.