Kolishetti, Nagesh

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Kolishetti, Nagesh Graduate Faculty

Positions

Assistant Professor, Immunology and Nano-Medicine , Herbert Wertheim College of Medicine

nkolishe@fiu.edu

biography

Nagesh Kolishetti, PhD, is an Assistant Professor in the Department of Immunology and Nano-Medince at the College of Medicine, FIU. Kolishetti completed his Masters in Chemistry and Ph.D in the area of Polymer Science. Kolishetti's postdoctoral training was focused in the areas of Nanomedicine and Drug Delivery. Before joining FIU, Kolishetti was leading the chemistry division at Partikula LLC, a startup company focused in developing mitochondria targeted therapeutics, platinum prodrugs and metabolic modulators. Kolishetti's current research focus is in the areas of polymer science and nanomedicine with applications in cancer and HIV/AIDS.

selected scholarly works & creative activities

Article
- 2023
  
  Anti-inflammatory effects of CBD in human microglial cell line infected with HIV-1
  Full Text via DOI: 10.1038/s41598-023-32927-4
- 2022
  
  Restoring the neuroprotective capacity of glial cells under opioid addiction
  Full Text via DOI: 10.1016/j.addicn.2022.100027
- 2022
  
  Intersection of Inorganic Chemistry and Nanotechnology for the Creation of New Cancer Therapies
  Full Text via DOI: 10.1021/accountsmr.1c00178 Web of Science: 000777724300002
- 2021
  
  Blending of Designer Synthetic Polymers to a Dual Targeted Nanoformulation for SARS-CoV-2 Associated Kidney Damage
  Full Text via DOI: 10.1021/acs.biomac.1c00799 Web of Science: 000708389300017
- 2021
  
  Brain-Accumulating Nanoparticles for Assisting Astrocytes to Reduce Human Immunodeficiency Virus and Drug Abuse-Induced Neuroinflammation and Oxidative Stress. ACS NANO. 15:15741-15753.
  Full Text via DOI: 10.1021/acsnano.0c09553 Web of Science: 000711790600023
- 2020
  
  Metabolic Modulation of the Tumor Microenvironment Leads to Multiple Checkpoint Inhibition and Immune Cell Infiltration. ACS NANO. 14:11055-11066.
  Full Text via DOI: 10.1021/acsnano.9b10037 Web of Science: 000615918600004
- 2020
  
  Inhibition of Amyloid-Beta Production, Associated Neuroinflammation, and Histone Deacetylase 2-Mediated Epigenetic Modifications Prevent Neuropathology in Alzheimer's Disease in vitro Model. FRONTIERS IN AGING NEUROSCIENCE. 11.
  Full Text via DOI: 10.3389/fnagi.2019.00342 Web of Science: 000509916900001
- 2019
  
  MRI-Guided, Noninvasive Delivery of Magneto-Electric Drug Nanocarriers to the Brain in a Nonhuman Primate. ACS APPLIED BIO MATERIALS. 2:4826-4836.
  Full Text via DOI: 10.1021/acsabm.9b00592 Web of Science: 000616372000019
- 2019
  
  Orally Administrable Therapeutic Synthetic Nanoparticle for Zika Virus. ACS NANO. 13:11034-11048.
  Full Text via DOI: 10.1021/acsnano.9b02807 Web of Science: 000492801600016
- 2018
  
  Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 115:E12333-E12342.
  Full Text via DOI: 10.1073/pnas.1816429115 Web of Science: 000454302600027
- 2018
  
  A designer bow-tie combination therapeutic platform: An approach to resistant cancer treatment by simultaneous delivery of cytotoxic and anti-inflammatory agents and radiation. BIOMATERIALS. 187:117-129.
  Full Text via DOI: 10.1016/j.biomaterials.2018.08.062 Web of Science: 000449446000012
- 2018
  
  Reduction of Cisplatin-Induced Ototoxicity without Compromising Its Antitumor Activity. BIOCHEMISTRY. 57:6500-6513.
  Full Text via DOI: 10.1021/acs.biochem.8b00712 Web of Science: 000451245600005
- 2018
  
  Core hydrophobicity tuning of a self-assembled particle results in efficient lipid reduction and favorable organ distribution. NANOSCALE. 10:366-377.
  Full Text via DOI: 10.1039/c7nr06295h Web of Science: 000418621000039
- 2017
  
  A Prodrug of Two Approved Drugs, Cisplatin and Chlorambucil, for Chemo War Against Cancer. MOLECULAR CANCER THERAPEUTICS. 16:625-636.
  Full Text via DOI: 10.1158/1535-7163.MCT-16-0445 Web of Science: 000398815800007
- 2017
  
  Photocurrent imaging of phase segregation in a ternary polymer blend induced via a non-solvent route
  Full Text via DOI: 10.1007/s10965-017-1187-6 Web of Science: 000411285500001
- 2016
  
  Controlled Multi-functionalization Facilitates Targeted Delivery of Nanoparticles to Cancer Cells. CHEMISTRY-A EUROPEAN JOURNAL. 22:1415-1423.
  Full Text via DOI: 10.1002/chem.201503999 Web of Science: 000368922500030
- 2015
  
  Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. NATURE COMMUNICATIONS. 6.
  Full Text via DOI: 10.1038/ncomms9692 Web of Science: 000364937600006
- 2015
  
  Evaluation of nanoparticle delivered cisplatin in beagles. NANOSCALE. 7:13822-13830.
  Full Text via DOI: 10.1039/c5nr03447g Web of Science: 000359546900003
- 2014
  
  Development of Therapeutic Polymeric Nanoparticles for the Resolution of Inflammation. ADVANCED HEALTHCARE MATERIALS. 3:1448-1456.
  Full Text via DOI: 10.1002/adhm.201300688 Web of Science: 000341907800014
- 2014
  
  Exploring Strain-Promoted 1,3-Dipolar Cycloadditions of End Functionalized Polymers. CHEMISTRY-A EUROPEAN JOURNAL. 20:8753-8760.
  Full Text via DOI: 10.1002/chem.201402225 Web of Science: 000338768900035
- 2013
  
  Multifunctionalization of Polymers by Strain-Promoted Cycloadditions. MACROMOLECULES. 46:7759-7768.
  Full Text via DOI: 10.1021/ma400913a Web of Science: 000326355200019
- 2013
  
  Nanocarriers for Tracking and Treating Diseases. CURRENT MEDICINAL CHEMISTRY. 20:3500-3514.
  Full Text via DOI: 10.2174/0929867311320280007 Web of Science: 000322573700007
- 2012
  
  alpha(V)beta(3) Integrin-Targeted PLGA-PEG Nanoparticles for Enhanced Anti-tumor Efficacy of a Pt(IV) Prodrug. ACS NANO. 6:4530-4539.
  Full Text via DOI: 10.1021/nn301148e Web of Science: 000304231700098
- 2011
  
  Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 108:1850-1855.
  Full Text via DOI: 10.1073/pnas.1011379108 Web of Science: 000286804700022
- 2010
  
  Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 107:17939-17944.
  Full Text via DOI: 10.1073/pnas.1011368107 Web of Science: 000283184800020
- 2008
  
  Structure-Reactivity Scales in Carbocationic Polymerizations. MACROMOLECULES. 41:9025-9029.
  Full Text via DOI: 10.1021/ma801669t Web of Science: 000261335100015
- 2008
  
  Relative reactivities of isobutylene, styrene, and ring-substituted styrenes in cationic polymerizations. MACROMOLECULES. 41:3842-3851.
  Full Text via DOI: 10.1021/ma800120h Web of Science: 000256393500018
- 2007
  
  Effect of surfactants on the fluorescence spectra of water-soluble MEHPPV derivatives having grafted polyelectrolyte chains
  Full Text via DOI: 10.1007/s12039-007-0026-4 Web of Science: 000246347200017
- 2007
  
  An efficient bulk-heterojunction photovoltaic cell based on energy transfer in graded-bandgap polymers. ADVANCED FUNCTIONAL MATERIALS. 17:226-232.
  Full Text via DOI: 10.1002/adfm.200600183 Web of Science: 000244171800006
- 2007
  
  Tunable two-colour patterning of MEHPPV from a single precursor. JOURNAL OF MATERIALS CHEMISTRY. 17:1682-1686.
  Full Text via DOI: 10.1039/b614876j Web of Science: 000245946800006
- 2003
  
  Segmented poly [2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene] via xanthate and dithiocarbamate precursors: A comparative study of thermal eliminations. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY. 41:3929-3940.
  Full Text via DOI: 10.1002/pola.10974 Web of Science: 000186853300008
Book Chapter
- 2012
  
  Nanoparticles for Targeted and Temporally Controlled Drug Delivery. 9-29.
  Full Text via DOI: 10.1007/978-1-4614-2305-8_2 Web of Science: 000303542200002
- 2011
  
  Biodistribution and Pharmacokinetics of Nanoprobes. 75-104.
  Web of Science: 000336989900005
Conference
- 2019
  
  Blood-brain barrier crossing nanoparticle for the delivery of antiretrovirals for targeting HIV-infected brain reservoirs. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000478861205620
- 2013
  
  Copper-free clickable initiators and chain transfer agents for ROP and RAFT polymerizations. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000324303605142
- 2013
  
  Multifunctionalization of polymers through sequential copper-free click reactions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000324303605141
- 2007
  
  POLY 101-Relative reactivity of cationic monomers: Isobutylene, styrene and ring substituted styrenes. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
  Web of Science: 000207593908602
- 2005
  
  Grafting functional handles on to MEHPPV - Possible application for sensing. 320-323.
  Full Text via DOI: 10.1016/j.synthmet.2005.01.037 Web of Science: 000234150000021
- 2005
  
  Modulating phase-separation in blends of MEHPPV-x with different conjugation lengths. 295-298.
  Full Text via DOI: 10.1016/j.synthmet.2005.01.040 Web of Science: 000234150000015
Review
- 2023
  
  Multi-functional auto-fluorescent nanogels for theranostics.. JOURNAL OF NEUROVIROLOGY.
  Full Text via DOI: 10.1007/s13365-023-01138-y
- 2022
  
  Cannabidiol for neurodegenerative disorders: A comprehensive review
  Full Text via DOI: 10.3389/fphar.2022.989717 Web of Science: 000881787300001
- 2022
  
  Controlled release nanoplatforms for three commonly used chemotherapeutics
  Full Text via DOI: 10.1016/j.mam.2021.101043 Web of Science: 000800541300005
- 2022
  
  Recent advances, status, and opportunities of magneto-electric nanocarriers for biomedical applications
  Full Text via DOI: 10.1016/j.mam.2021.101046 Web of Science: 000800538800001
- 2016
  
  Nanotechnology inspired tools for mitochondrial dysfunction related diseases. ADVANCED DRUG DELIVERY REVIEWS. 52-69.
  Full Text via DOI: 10.1016/j.addr.2015.12.024 Web of Science: 000374370700005
- 2015
  
  Targeted nanoparticles in mitochondrial medicine. 315-329.
  Full Text via DOI: 10.1002/wnan.1305 Web of Science: 000352811000005
- 2010
  
  Emerging nanotechnology approaches for HIV/AIDS treatment and prevention. NANOMEDICINE. 269-285.
  Full Text via DOI: 10.2217/NNM.10.1 Web of Science: 000275006300015

principal investigator on

Development of Brain Targeted and Biodegradable Polymeric Nano-Formulations for Delivery of Antiretroviral Drugs and Neuroprotectants awarded by FIU Foundation 2018 - 2021

full name

Nagesh Kolishetti

ORCID iD

https://orcid.org/0000-0001-5574-673X (confirmed)

visualizations

Co-author Network

Co-investigator Network

publication subject areas

Citation index-derived subject areas the researcher has published in