Drug Metabolism And Disposition

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Drug Metabolism And Disposition Journal

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Inhibitory effects of Δ8-tetrahydrocannabinol on major hepatic cytochrome P450 enzymes and implications for drug disposition.. 53:100122. 2025
Hydroxylation near the epoxyketone of carfilzomib confers protection from microsomal epoxide hydrolase-mediated metabolism. 53. 2025
Identification of human hepatic UDP-glucuronosyltransferases involved in the glucuronidation of temazepam.. 53:100104. 2025
HCV Antiviral Drugs Have the Potential to Adversely Perturb the Fetal-Maternal Communication Axis through Inhibition of CYP3A7 DHEA-S Oxidation. 52:516-525. 2024
Characterization of Cytosolic Glutathione S-Transferases Involved in the Metabolism of the Aromatase Inhibitor, Exemestane.. 49:1047-1055. 2021
Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome-Related Aqueous Metabolites in Mice. 47:928-940. 2019
PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice. 46:1226-1240. 2018
Alteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing Brain. 41:326-331. 2013
Epigenetic Regulation of Multidrug Resistance Protein 1 and Breast Cancer Resistance Protein Transporters by Histone Deacetylase Inhibition 2020
CYP2C19 Plays a Major Role in the Hepatic <i>N</i>-Oxidation of Cotinine. 2023
Cannabinoid Metabolites as Inhibitors of Major Hepatic CYP450 Enzymes, with Implications for Cannabis-Drug Interactions. 2021
Inhibition of UDP-Glucuronosyltransferase Enzymes by Major Cannabinoids and Their Metabolites. 2021
UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues. 2020
Role of l- and d-Menthol in the Glucuronidation and Detoxification of the Major Lung Carcinogen, NNAL. 2019
Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors. 2019
Identification and Quantification of Novel Major Metabolites of the Steroidal Aromatase Inhibitor, Exemestane. 2018
Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product-Drug Interaction. 2015
Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation. 2014
UGT2B gene expression analysis in multiple tobacco carcinogen-targeted tissues. 2014
Importance of UDP-glucuronosyltransferases 2A2 and 2A3 in tobacco carcinogen metabolism. 2013
Sex differences in UDP-glucuronosyltransferase 2B17 expression and activity. 2010
UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility. 2010
Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene. 2009
Glucuronidation of tobacco-specific nitrosamines by UGT2B10. 2008
Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases. 2007
Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. 2007
Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform. 2006
Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: importance of UDP-glucuronosyltransferase 1A4. 2004
Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues. 2002
O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9. 2000
Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by rat UDP-glucuronosyltransferase 2B1. 1999

International Standard Serial Number (ISSN)

0090-9556

Electronic International Standard Serial Number (EISSN)

1521-009X