Model Substrate/Inactivation Reactions for MoaA and Ribonucleotide Reductases: Loss of Bromo, Chloro, or Tosylate Groups from C2 of 1,5-Dideoxyhomoribofuranoses upon Generation of an alpha-Oxy Radical at C3 Article

Wnuk, Stanislaw F, Mudgal, Mukesh M, Nowak, Ireneusz et al. (2020). Model Substrate/Inactivation Reactions for MoaA and Ribonucleotide Reductases: Loss of Bromo, Chloro, or Tosylate Groups from C2 of 1,5-Dideoxyhomoribofuranoses upon Generation of an alpha-Oxy Radical at C3 . 25(11), 10.3390/molecules25112539

Open Access

cited authors

  • Wnuk, Stanislaw F; Mudgal, Mukesh M; Nowak, Ireneusz; Robins, Morris J

sustainable development goals

authors

publication date

  • June 1, 2020

webpage

keywords

  • 5-DIPHOSPHATE
  • ABSTRACTION
  • ACID RELATED-COMPOUNDS
  • ACTIVE-SITE
  • Biochemistry & Molecular Biology
  • Chemistry
  • Chemistry, Multidisciplinary
  • ESCHERICHIA-COLI
  • Life Sciences & Biomedicine
  • MECHANISM-BASED INACTIVATION
  • MUTANT
  • NUCLEOSIDE
  • Physical Sciences
  • REDUCTION
  • Science & Technology
  • THIYL
  • biomimetic modeling
  • biosynthesis of molybdopterin
  • carbohydrates
  • mechanism-based enzyme inhibition
  • oxyl radicals
  • radical chemistry
  • ribonucleotide reductases

Digital Object Identifier (DOI)

publisher

  • MDPI

volume

  • 25

issue

  • 11