Comparison of dried matrix spots and fabric phase sorptive extraction methods for quantification of highly potent analgesic activity agent (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol in rat whole blood and plasma using LC-MS/MS Article

Lastovka, Anastasiya V, Rogachev, Artem D, Il'ina, Irina V et al. (2019). Comparison of dried matrix spots and fabric phase sorptive extraction methods for quantification of highly potent analgesic activity agent (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol in rat whole blood and plasma using LC-MS/MS . JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1132 10.1016/j.jchromb.2019.121813

International Collaboration

cited authors

  • Lastovka, Anastasiya V; Rogachev, Artem D; Il'ina, Irina V; Kabir, Abuzar; Volcho, Konstantin P; Fadeeva, Valentina P; Pokrovsky, Andrey G; Furton, Kenneth G; Salakhutdinov, Nariman F

publication date

  • November 15, 2019

keywords

  • (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol
  • AFATINIB
  • ARRAY DETECTION METHOD
  • ASSAY
  • Analgesic agent
  • Biochemical Research Methods
  • Biochemistry & Molecular Biology
  • Chemistry
  • Chemistry, Analytical
  • DRUGS
  • Dried matrix spots
  • FPSE biofluid sampler
  • Fabric phase sorptive extraction
  • LC-MS/MS
  • LIQUID
  • Life Sciences & Biomedicine
  • MASS-SPECTROMETRY
  • METABOLITES
  • Physical Sciences
  • RAPID-DETERMINATION
  • Science & Technology
  • VALIDATION

Digital Object Identifier (DOI)

publisher

  • ELSEVIER

volume

  • 1132