Stereoselective synthesis of sugar-modified enyne analogues of adenosine and uridine. Interaction with S-adenosyl-L-homocysteine hydrolase and antiviral and cytotoxic effects Article

Wnuk, SF, Lewandowska, E, Sacasa, PR et al. (2004). Stereoselective synthesis of sugar-modified enyne analogues of adenosine and uridine. Interaction with S-adenosyl-L-homocysteine hydrolase and antiviral and cytotoxic effects . JOURNAL OF MEDICINAL CHEMISTRY, 47(21), 5251-5257. 10.1021/jm040054+

International Collaboration

cited authors

  • Wnuk, SF; Lewandowska, E; Sacasa, PR; Crain, LN; Zhang, JS; Borchardt, RT; De Clercq, E

sustainable development goals

authors

publication date

  • October 7, 2004

published in

keywords

  • ACID RELATED-COMPOUNDS
  • ADENOSYLHOMOCYSTEINE HYDROLASE
  • CRYSTAL-STRUCTURE
  • Chemistry, Medicinal
  • DESIGN
  • HYDROLYTIC ACTIVITY
  • INACTIVATION
  • Life Sciences & Biomedicine
  • MECHANISM-BASED INHIBITORS
  • NUCLEOSIDES
  • Pharmacology & Pharmacy
  • SUBSTRATE-BINDING
  • Science & Technology

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 5251

end page

  • 5257

volume

  • 47

issue

  • 21