Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase Article

Musilek, Kamil, Holas, Ondrej, Kuca, Kamil et al. (2008). Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase . 23(1), 70-76. 10.1080/14756360701383981

Open Access

cited authors

  • Musilek, Kamil; Holas, Ondrej; Kuca, Kamil; Jun, Daniel; Dohnal, Vlastimil; Opletalova, Veronika; Dolezal, Martin

sustainable development goals

authors

publication date

  • January 1, 2008

webpage

keywords

  • AMINO-ACID-RESIDUES
  • BIOLOGICAL-ACTIVITY
  • BIS-PYRIDINIUM MONOOXIMES
  • Biochemistry & Molecular Biology
  • CHOLINESTERASES
  • CRYSTAL-STRUCTURES
  • Chemistry, Medicinal
  • Life Sciences & Biomedicine
  • MONOQUATERNARY
  • NERVE AGENT
  • OXIMES
  • Pharmacology & Pharmacy
  • QUATERNARY-SALTS
  • Science & Technology
  • XYLENE LINKER
  • acetylcholinesterase
  • inhibition
  • nerve agent
  • oxime
  • paraoxon
  • pesticide
  • reactivation
  • reactivator
  • tabun

Digital Object Identifier (DOI)

publisher

  • TAYLOR & FRANCIS LTD

start page

  • 70

end page

  • 76

volume

  • 23

issue

  • 1