SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides Article

Gorecki, Lukas, Korabecny, Jan, Musilek, Kamil et al. (2016). SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides . ARCHIVES OF TOXICOLOGY, 90(12), 2831-2859. 10.1007/s00204-016-1827-3

cited authors

  • Gorecki, Lukas; Korabecny, Jan; Musilek, Kamil; Malinak, David; Nepovimova, Eugenie; Dolezal, Rafael; Jun, Daniel; Soukup, Ondrej; Kuca, Kamil

sustainable development goals

authors

publication date

  • December 1, 2016

published in

keywords

  • Acetylcholinesterase
  • BIS-PYRIDINIUM OXIMES
  • BLOOD-BRAIN-BARRIER
  • CHEMICAL WARFARE AGENTS
  • EFFICIENT UNCHARGED REACTIVATORS
  • ELECTRIC-EEL ACETYLCHOLINESTERASE
  • IN-VITRO EVALUATION
  • INHIBITED HUMAN ACETYLCHOLINESTERASE
  • Life Sciences & Biomedicine
  • Nerve agents
  • Organophosphate
  • Pyridinium oximes
  • Reactivation
  • SILICO PHARMACOPHORE MODEL
  • STEERED MOLECULAR-DYNAMICS
  • Science & Technology
  • TORPEDO-CALIFORNICA ACETYLCHOLINESTERASE
  • Toxicology
  • Uncharged reactivator

Digital Object Identifier (DOI)

publisher

  • SPRINGER HEIDELBERG

start page

  • 2831

end page

  • 2859

volume

  • 90

issue

  • 12