Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents Article

Zorbaz, Tamara, Malinak, David, Marakovic, Nikola et al. (2018). Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents . JOURNAL OF MEDICINAL CHEMISTRY, 61(23), 10753-10766. 10.1021/acs.jmedchem.8b01398

International Collaboration

cited authors

  • Zorbaz, Tamara; Malinak, David; Marakovic, Nikola; Hrvat, Nikolina Macek; Zandona, Antonio; Novotny, Michal; Skarka, Adam; Andrys, Rudolf; Benkova, Marketa; Soukup, Ondrej; Katalinic, Maja; Kuca, Kamil; Kovarik, Zrinka; Musilek, Kamil

sustainable development goals

authors

publication date

  • December 13, 2018

webpage

published in

keywords

  • BISPYRIDINIUM OXIMES
  • CURRENTLY USED OXIMES
  • Chemistry, Medicinal
  • FLUORINATED ANALOG KR-22836
  • HI-6
  • IN-VITRO
  • K203
  • Life Sciences & Biomedicine
  • OBIDOXIME
  • Pharmacology & Pharmacy
  • RAT-BRAIN ACETYLCHOLINESTERASE
  • Science & Technology
  • TABUN
  • UNCHARGED REACTIVATORS

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 10753

end page

  • 10766

volume

  • 61

issue

  • 23