Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17 beta-HSD10 with Implications to Alzheimer's Disease Treatment Article

Schmidt, Monika, Benek, Ondrej, Vinklarova, Lucie et al. (2020). Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17 beta-HSD10 with Implications to Alzheimer's Disease Treatment . 21(6), 10.3390/ijms21062059

Open Access International Collaboration

cited authors

  • Schmidt, Monika; Benek, Ondrej; Vinklarova, Lucie; Hrabinova, Martina; Zemanova, Lucie; Chribek, Matej; Kralova, Vendula; Hroch, Lukas; Dolezal, Rafael; Lycka, Antonin; Prchal, Lukas; Jun, Daniel; Aitken, Laura; Gunn-Moore, Frank; Kuca, Kamil; Musilek, Kamil

sustainable development goals

authors

publication date

  • March 1, 2020

keywords

  • 17 beta-hydroxysteroid dehydrogenase type 10
  • ABAD
  • ABAD/17-BETA-HSD10
  • ACID
  • AMYLOID-BETA-PEPTIDE
  • Alzheimer's disease
  • BINDING
  • Biochemistry & Molecular Biology
  • COENZYME-A DEHYDROGENASE
  • CRYSTAL-STRUCTURE
  • Chemistry
  • Chemistry, Multidisciplinary
  • DESIGN
  • ENZYME
  • IDENTIFICATION
  • Life Sciences & Biomedicine
  • OXIDATION
  • Physical Sciences
  • Science & Technology
  • benzothiazole
  • inhibitor
  • neurodegeneration

Digital Object Identifier (DOI)

publisher

  • MDPI

volume

  • 21

issue

  • 6