Biophysical Kv3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer's Article

Olah, Viktor J, Goettemoeller, Annie M, Rayaprolu, Sruti et al. (2022). Biophysical Kv3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer's . eLife, 11 10.7554/eLife.75316

Open Access

cited authors

  • Olah, Viktor J; Goettemoeller, Annie M; Rayaprolu, Sruti; Dammer, Eric B; Seyfried, Nicholas T; Rangaraju, Srikant; Dimidschstein, Jordane; Rowan, Matthew JM

authors

publication date

  • June 21, 2022

published in

keywords

  • ACTION-POTENTIAL GENERATION
  • APP
  • AXON INITIAL SEGMENT
  • Biology
  • FAST-SPIKING
  • GABAERGIC INTERNEURONS
  • GATED K+ CHANNELS
  • INHIBITORY INTERNEURONS
  • K(v)3
  • Life Sciences & Biomedicine
  • Life Sciences & Biomedicine - Other Topics
  • MOUSE MODEL
  • Mouse
  • NEURONAL HYPEREXCITABILITY
  • PARVALBUMIN-POSITIVE INTERNEURONS
  • POTASSIUM CHANNEL
  • Science & Technology
  • action potential
  • gamma
  • mass spectrometry
  • parvalbumin

Digital Object Identifier (DOI)

publisher

  • eLIFE SCIENCES PUBL LTD

volume

  • 11