A gated hydrophobic funnel within BAX binds bioactive lipids to potentiate pro-apoptotic function Article

Gelles, Jesse D, Chen, Yiyang, Luna-Vargas, Mark PA et al. (2026). A gated hydrophobic funnel within BAX binds bioactive lipids to potentiate pro-apoptotic function . NATURE COMMUNICATIONS, 17(1), 10.1038/s41467-026-69836-9

Open Access

cited authors

  • Gelles, Jesse D; Chen, Yiyang; Luna-Vargas, Mark PA; Follis, Ariele Viacava; Al Noman, Md Abdullah; Kabir, Md; Bayiokos, Stella G; Mohammed, Jarvier N; Sebastian, Tara M; Pham, Ngoc Dung; Shi, Yi; Jin, Jian; Kriwacki, Richard W; Chipuk, Jerry Edward

sustainable development goals

authors

publication date

  • February 25, 2026

published in

keywords

  • 1-PHOSPHATE BREAKDOWN PRODUCT
  • ADDUCTS
  • BIM
  • DIRECT ACTIVATION
  • MEMBRANE PERMEABILIZATION
  • MOLECULAR-MECHANISMS
  • MUTATIONS
  • Multidisciplinary Sciences
  • OLIGOMERIZATION
  • REORGANIZATION
  • Science & Technology
  • Science & Technology - Other Topics
  • TOXICITY

Digital Object Identifier (DOI)

publisher

  • NATURE PORTFOLIO

volume

  • 17

issue

  • 1