Trpv4-mediated mechanotransduction regulates the differentiation of valvular interstitial cells to myofibroblasts: implications for aortic valve stenosis Article

Mukherjee, Pritha, Mahanty, Manisha, Dutta, Bidisha et al. (2025). Trpv4-mediated mechanotransduction regulates the differentiation of valvular interstitial cells to myofibroblasts: implications for aortic valve stenosis . American Journal of Physiology - Cell Physiology, 328(5), C1558-C1570. 10.1152/ajpcell.00977.2024

Open Access

cited authors

  • Mukherjee, Pritha; Mahanty, Manisha; Dutta, Bidisha; Rahaman, Suneha G; Sankaran, Karunakaran R; Liu, Zhenguo; Rahaman, Shaik O

sustainable development goals

authors

publication date

  • May 9, 2025

published in

keywords

  • ACTIVATION
  • CHANNEL
  • Cell Biology
  • DISEASE
  • EPITHELIAL-MESENCHYMAL TRANSITION
  • EXTRACELLULAR-MATRIX
  • FIBROSIS
  • Life Sciences & Biomedicine
  • MECHANISMS
  • Physiology
  • RISK
  • SUBSTRATE STIFFNESS
  • Science & Technology
  • YAP/TAZ
  • aortic valve stenosis
  • mechanotransduction
  • traction force microscopy
  • transient receptor potential vanilloid 4
  • valvular interstitial cell

Digital Object Identifier (DOI)

publisher

  • AMER PHYSIOLOGICAL SOC

start page

  • C1558

end page

  • C1570

volume

  • 328

issue

  • 5