Reddy Sankaran, Karunakaran

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Reddy Sankaran, Karunakaran

Positions

Postdoctoral Associate, Department of Cellular and Molecular Medicine , Herbert Wertheim College of Medicine

kreddysa@fiu.edu

selected scholarly works & creative activities

Article
- 2025
  
  TRPV4-Mediated Mechanosensing Regulates the Endothelial-to-Mesenchymal Transition: Implications for Atherosclerosis. FASEB JOURNAL. 39.
  Full Text via DOI: 10.1096/fj.202403198R Web of Science: 001637482900001
- 2025
  
  Synthesis, Anticancer and Antiadipogenic Activity of Curcumin Linked 1,2,3,4-Tetrazole Derivatives. Journal of Heterocyclic Chemistry. 62:994-1011.
  Full Text via DOI: 10.1002/jhet.70051 Web of Science: 001541441400001
- 2025
  
  Trpv4-mediated mechanotransduction regulates the differentiation of valvular interstitial cells to myofibroblasts: implications for aortic valve stenosis. American Journal of Physiology - Cell Physiology. 328:C1558-C1570.
  Full Text via DOI: 10.1152/ajpcell.00977.2024 Web of Science: 001484061200001
- 2024
  
  Astragalin and rutin restore gut microbiota dysbiosis, alleviate obesity and insulin resistance in high-fat diet-fed C57BL/6J mice. Food Science and Human Wellness. 13:3256-3265.
  Full Text via DOI: 10.26599/FSHW.2023.9250012 Web of Science: 001386531400005
- 2024
  
  Avocado-derived extracellular vesicles loaded with ginkgetin and berberine prevent inflammation and macrophage foam cell formation. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 28.
  Full Text via DOI: 10.1111/jcmm.18177 Web of Science: 001186175600001
- 2024
  
  Thymoquinone mitigates obesity and diabetic parameters through regulation of major adipokines, key lipid metabolizing enzymes and AMPK/p-AMPK in diet-induced obese rats. 3 BIOTECH. 14.
  Full Text via DOI: 10.1007/s13205-023-03847-x Web of Science: 001127272700001
- 2023
  
  Ursolic acid regulates key EMT transcription factors, induces cell cycle arrest and apoptosis in MDA-MB-231 and MCF-7 breast cancer cells, an in-vitro and in silico studies. JOURNAL OF CELLULAR BIOCHEMISTRY. 124:1900-1918.
  Full Text via DOI: 10.1002/jcb.30496 Web of Science: 001108238900001
- 2023
  
  Anti-adipogenic and lipid-lowering activity of piperine and epigallocatechin gallate in 3T3-L1 adipocytes. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY. 129:1152-1159.
  Full Text via DOI: 10.1080/13813455.2021.1908366 Web of Science: 000639003200001
- 2023
  
  Quercetin-3-O-rutinoside from Moringa oleifera Downregulates Adipogenesis and Lipid Accumulation and Improves Glucose Uptake by Activation of AMPK/Glut-4 in 3T3-L1 Cells. Revista Brasileira de Farmacognosia. 33:334-343.
  Full Text via DOI: 10.1007/s43450-022-00352-9 Web of Science: 000933159800001
- 2023
  
  Capparis zeylanica L. root extract promotes apoptosis and cell cycle arrest, inhibits epithelial-to-mesenchymal transition and triggers E-cadherin expression in breast cancer cell lines. 3 BIOTECH. 13.
  Full Text via DOI: 10.1007/s13205-023-03461-x Web of Science: 000911996100001
- 2021
  
  Anti-Obesity and Lipid Lowering Activity of Bauhiniastatin-1 is Mediated Through PPAR-γ/AMPK Expressions in Diet-Induced Obese Rat Model. FRONTIERS IN PHARMACOLOGY. 12.
  Full Text via DOI: 10.3389/fphar.2021.704074 Web of Science: 000683744500001
- 2021
  
  A bioactive fraction of Pterocarpus santalinus inhibits adipogenesis and inflammation in 3T3-L1 cells via modulation of PPAR-γ/SREBP-1c and TNF-α/IL-6. 3 BIOTECH. 11.
  Full Text via DOI: 10.1007/s13205-021-02771-2 Web of Science: 000642913700001
- 2019
  
  Catalyst-Free Synthesis of Xanthene and Pyrimidine-Fused Heterocyclic Derivatives at Water-Ethanol Medium and Their Antioxidant Properties. ChemistrySelect. 4:644-649.
  Full Text via DOI: 10.1002/slct.201803449 Web of Science: 000456211600028
- 2019
  
  Tephrosia purpurea Fraction Attenuates Lipid Accumulation and Adipogenesis in 3T3-L1 Adipocytes and Reduces Body Weight in High Fat Diet Induced Obese Rats. Advances in Bioscience and Biotechnology. 10:288-304.
  Full Text via DOI: 10.4236/abb.2019.109023
Book Chapter
- 2019
  
  Recent Developments in the Prevention of Obesity by Using Microorganisms. 47-60.
  Full Text via DOI: 10.1016/B978-0-12-816328-3.00005-2 Web of Science: 000467859900007
Preprint
- 2026
  
  A novel role for TRPV1 in macrophage giant cell formation.
  Full Text via DOI: 10.64898/2026.05.11.724406
- 2026
  
  A novel endosome-escaping, macrophage-targeted nanoparticle platform for miR-146a delivery with favorable in vivo biodistribution and biocompatibility.
  Full Text via DOI: 10.64898/2026.02.23.707596
- 2026
  
  Endosome-escaping engineered LNP-miR146a with in vivo biodistribution to mitigate inflammation and foreign body giant cell formation.
  Full Text via DOI: 10.64898/2026.02.13.705811
Review
- 2025
  
  Molecular signaling in biomaterial-induced foreign body response: current perspectives. American Journal of Physiology - Cell Physiology. C1468-C1486.
  Full Text via DOI: 10.1152/ajpcell.00595.2025 Web of Science: 001620748300002
- 2018
  
  ENHANCED HUMAN EXPOSURE TO RADIATIONS, ROLE OF PHYTOCHEMICALS AS POTENTIAL RADIO-PROTECTANTS: A REVIEW. International Journal of Pharmaceutical Sciences and Research. 2656-2668.
  Full Text via DOI: 10.13040/IJPSR.0975-8232.9(7).2656-68 Web of Science: 000437524800006

full name

Karunakaran Reddy Sankaran

ORCID iD

https://orcid.org/0000-0003-4559-0107 (confirmed)

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