Structural Remodeling of TCR-HLA-DQ8 Recognition by a β-Cell Stress-Associated C19S Insulin Neoepitope in Type 1 Diabetes Article

Mittal, Rahul, Alipour, Farhad, Chapagain, Prem et al. (2026). Structural Remodeling of TCR-HLA-DQ8 Recognition by a β-Cell Stress-Associated C19S Insulin Neoepitope in Type 1 Diabetes . International Journal of Molecular Sciences, 27(15), 10.3390/ijms27156556

cited authors

  • Mittal, Rahul; Alipour, Farhad; Chapagain, Prem; Hirani, Khemraj

authors

publication date

  • July 23, 2026

published in

keywords

  • Biochemistry & Molecular Biology
  • CD4(+) T-CELLS
  • Chemistry
  • Chemistry, Multidisciplinary
  • GROMACS
  • HLA-DQ8
  • Life Sciences & Biomedicine
  • MHC CLASS-II
  • Physical Sciences
  • STABILITY
  • Science & Technology
  • T cell receptor recognition
  • autoreactive CD4+T cells
  • beta-cell stress
  • insulin autoimmunity
  • molecular dynamics simulation
  • neoepitope
  • peptide-HLA interface
  • type 1 diabetes

Digital Object Identifier (DOI)

publisher

  • MDPI

volume

  • 27

issue

  • 15