Discovery of a novel benzofuran-7-carboxamide-based PARP1/c-Met dual inhibitor for addressing c-Met amplification-mediated PARP1i acquired-resistance Article

Sun, Zeren, Hu, Mengxuan, Xu, Jie et al. (2025). Discovery of a novel benzofuran-7-carboxamide-based PARP1/c-Met dual inhibitor for addressing c-Met amplification-mediated PARP1i acquired-resistance . EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 300 10.1016/j.ejmech.2025.118164

cited authors

  • Sun, Zeren; Hu, Mengxuan; Xu, Jie; Zhai, Bingxin; Zhang, Yuchen; Zhang, Wenbin; Wang, Boning; Wang, Runyuan; Hu, Zheqi; Xu, Yungen; Zhu, Qihua; Zou, Yi

sustainable development goals

authors

publication date

  • December 15, 2025

published in

keywords

  • Acquired drug-resistance
  • Chemistry, Medicinal
  • Dual target inhibitor
  • IN-VITRO
  • Life Sciences & Biomedicine
  • PARP1
  • Pharmacology & Pharmacy
  • Science & Technology
  • c -Met

Digital Object Identifier (DOI)

publisher

  • ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER

volume

  • 300