Efficacy and safety of tenecteplase in ST elevation myocardial infarction patients from the Elaxim Indian Registry. Article

Iyengar, SS, Nair, Tiny, Sathyamurthy, I et al. Efficacy and safety of tenecteplase in ST elevation myocardial infarction patients from the Elaxim Indian Registry. . Indian Heart Journal, (5), -481.

cited authors

  • Iyengar, SS; Nair, Tiny; Sathyamurthy, I; Hiremath, JS; Jadhav, U; Kumbla, D; Jain, RK; Srinivasan, M; Sahoo, PK; Chawla, Kamaldeep; Katiyal, VK

abstract

  • Objective

    to study the efficacy and safety of indigenously developed tenecteplase injection in the management of Indian STEMI patients in clinical practice.

    Methods

    post-licensure, observational, prescription event monitoring study.

    Results

    2100 patients received weight-adjusted tenecteplase injection. More than 90% patients received aspirin, clopidogrel, and enoxaparin/heparin. Clinically successful thrombolysis was reported in 86.71%, in-hospital mortality was 3.48%. The adverse events recorded were comparable with previously published data. Any bleeding (excluding intra-cranial hemorrhage) was seen in 4.62% patients which was reported in 0.90% patients of which 47.34% patients had also received GpIIb/IIIa inhibitors.

    Conclusion

    This study confirms the efficacy and safety of indigenous tenecteplase in Indian STEMI patients.

authors

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keywords

  • Female
  • India
  • Male
  • Registries
  • Tenecteplase
  • Tissue Plasminogen Activator
  • Treatment Outcome

end page

  • 481

issue

  • 5