A unique battery-less multi-sensor (ECG, accelerometer and temperature) system that achieves one of the lowest operational power profiles for a multifunctional biomedical device is presented. This new low power characteristic is achieved by employing a FCC approved RF rectification and power management system coupled with low power wireless sensor data transmission. The device is powered by a RF energy harvester with a regulator that leads to a total power delivery of ∼ 9 mW. A STMicroelectronics ST1VAFE3BX sensor is used to measure biopotential and acceleration and the MAX30210 provides clinical grade temperature data. The entire multisensory suite is all-digital and requires only ∼ 200 μ A at 1.8 V (360 μ W). The sensor has 12bit ECG waveform, 16-bit accelerometer, and 16-bit bio-temperature resolutions. The biomarker data can be stored on-board using non-volatile memory (Nordic Semiconductor nRF54L) as part of a System on Chip (SoC) for off-board transmission via a Bluetooth.