Predictive Validity of the Obsessive-Compulsive Inventory-4 and Florida Obsessive-Compulsive Inventory-II Severity Scale
Article
Storch, Eric A, McCarty, Ryan J, Zehavi, Maya et al. (2025). Predictive Validity of the Obsessive-Compulsive Inventory-4 and Florida Obsessive-Compulsive Inventory-II Severity Scale
. Journal of Psychiatric Research, S0022-3956(25)00757-5. 10.1016/j.jpsychires.2025.12.011
Storch, Eric A, McCarty, Ryan J, Zehavi, Maya et al. (2025). Predictive Validity of the Obsessive-Compulsive Inventory-4 and Florida Obsessive-Compulsive Inventory-II Severity Scale
. Journal of Psychiatric Research, S0022-3956(25)00757-5. 10.1016/j.jpsychires.2025.12.011
Storch, Eric A; McCarty, Ryan J; Zehavi, Maya; Ahmad, Mahnoor; Cruz, Vanessa Zavala; Berrones, Dayan; Muñoz, Josselyn S; Obando, Diana; Barajas, Servando Rodriguez; Frederick, Renee M; Anderberg, Jacey L; Moore, Hannah C; Ochoa-Panaifo, Marcos E; Mallen, Mayra C Martinez; Onyeka, Ogechi; Wiese, Andrew D; Sagarnaga, Melisa N; McGuire, Joseph F; Ferrão, Ygor Arzeno; Goodman, Wayne K; Crowley, James J; Adorno, Victor R; Agostini, Victoria; Aguilar, William W; Aguirre, Cinthia; Alvarado-Quiroz, Valentina; Ancalade, NaEshia; Anciburo, Maria E; Anderberg, Jacey L; Antich, Amira Y; Aponte, Diego; Londoño, Jhon E Arango; Espinosa, Alejandro A Arellano; Arellano-Ramírez, Luisa; Arnold, Paul D; Carmelo, Brygith Asenjo; Atkinson, Elizabeth G; Avanesyan, Tatevik; Avery, Juliana E; Avila-Vazquez, Andrea F; Ayala, Jose N; Aziz, Hala; Aguirre, Tania L Barbieri; Barrera, Cynthia N; Contreras, Julian A Barrero; Barry, Kelly; Belanger, Amanda N; Benitez, Laura M; Berrones, Dayan; Best, John R; Bigdeli, Tim B; Bommiasamy, Hemamalini; Borda, Tania; Boyajian, Laura; Boyle, Nathan; Muñoz, Diego Briceño; Browning, Lauren; Burton, Christie L; Buxbaum, Joseph D; Rivera, Ricardo E Calderón; Callahan, Jennifer L; Gomez, Carlos A Camacho; Ponce, Laura A Campos; Canchari, Ernesto G; Torres, Roxana Carrasco; Catano-Cedillo, María L; Cervin, Matti; Chang, Alexandria; Cheng, Jessica SC; Chire, Jessica M; Muñoz, Macarena Churruca; Cicero, David C; Cifuentes-Espinoza, Amanda P; Quiroz, Pamela Claisse; Colombo, Gianna M; Comer, Jonathan S; Condori-Apaza, Luz; Cortina, Jennifer; Costa, Carolina; Crosbie, Jennifer; Crowley, James J; Cruz, Victor O; Cruz, Isabella A; Cunning, Allison; Perez, Guillermo J Dager; Dailey, Megan M; Dang, Brian D; Checco, Kelly L Davalos; Dawson, Alyssa; del Prado, Pavel; del Río, Daniela; Dev, Amelia; Diaz, Sara; Estrada, Florencia S; Figueroa, Edith G; Flecha, Letizia M; Flores-Garcia, Álvaro M; Franklin, Martin E; Frederick, Renee M; Fujita, Ricardo; Furr, Jami M; Gaeta, Alessa; Gamarra, Olivia M; Garay-Contreras, Camila; García-Bravo, Nataly; García-Jaimes, Cynthia; Garrison, Sheldon R; Giusti-Rodriguez, Paola; González, Andrés; Gonzalez-Barrios, Polaris; Goodman, Wayne K; Gorosito, Javier D; Grice, Dorothy E; Guintivano, Jerry; Guttfreund, Daniel G; Halvorsen, Matthew W; Miles, Jorge AR Haslop; Hernandez, Dariana G; Núñez, Estefanía V Hernández; Hettema, John M; Hovey, Joseph D; Ccarhuas, Bryan Huerta; Irreño-Sotomonte, Jonathan; Pedraza, Selva S Iturralde; Jagannathan, Nisha; Jensen, Matias; Jiwani, Rozmin B; Johnson, Jessica S; Joutteaux, Sonia; Lujambio, Joali Alexandra Juárez; Kehrer, Sabrina; Kennedy, James L; Lanzagorta, Nuria; Lázaro-Muñoz, Gabriel; Longhurst, Melanie O; Martinez, David A Lozada; Luna, Elba S; MacLellan, Anna; Marques, Andrea H; Martinez, Molly; Martínez, Galo N; Mallen, Mayra C Martinez; Martinez-Gonzalez, Karen G; de Los Angeles Matos, Maria; Mattheisen, Manuel; McCarty, Ryan J; McGuire, Joseph F; McKay, Dean; McOmber, Ciara; de Borja, Nancy E Melendez; Minaya, Charlene; Miño, Tomás; Mithani, Sara M; Zambrana, Mariana Monasterio; Moore, Hannah C; Morales-Rivero, Alonso; Moya, Pablo R; Moyano, Maria B; Mukunda, Pavithra; Muñoz, Josselyn S; Zabaleta, Maria J Muñoz; Nicolini, Humberto; Bracho, Ambar A Núñez; Bracho, Belinda E Núñez; Obando, Diana; Ochoa, Monica E; Ochoa-Panaifo, Marcos E; O'Higgins, Marcelo; Castaman, Luis A Olavarria; Balmaceda, Trinidad Olivos; Tobar, María J Olmedo; Onyeka, Ogechi C; Ortega, Iliana; Paredes-Linares, Vanessa S; Pato, Michele T; Pavlinusich, Ivana; Paz y Miño, Mariel; de Leon, Edilberto Peña; Orellana, José L Perales; Pereira, Stacey; Duarte, Tania Pérez; Phan, Angel; Placencia, Maritza; Ponce, Lorena; Poovey, Kendall; Qiao, Thomas; Quiroz-Padilla, Maria F; Correa, María F Quispe-; Heros, Alessandra S Ramirez; Valencia, Dayana A Ramírez; Ramos, Renato T; Ramos, Iaroslava C; Ramsey, Kesley A; Rancourt, Diana; Gomez, Sebastian Rebatta; Espinosa, Rocío C Reyes; Richter, Peggy; Rodriguez, Carolyn I; Barajas, Servando Rodriguez; Romero, Maritza J; Ruggero, Camilo J; Ruiz-Chow, Angel; Sagarnaga, Melisa N; Montoya, Gianella N Salazar; Salhadar, Nadeen; Schachar, Russell J; Segovia, Lucia M; Seligman, Laura D; Siegel, Isaac J; Spencer, Samuel D; Stewart, S Evelyn; Storch, Eric A; Tames-Bravo, Maria J; Tapia-Cuevas, Vissente; Thompson, Peter M; Timpano, Kiara R; Tonarelli, Silvina; la Garza, Beatriz Treviño-de; Trujillo, Angela; Villar, Constanza Uribe; Jardón, Carolina Valdés; Valentine, Keara; Vallejo-Silva, Alexie; van Roessel, Peter; Medrano, Javier Vargas; Vásquez-Suyo, María I; Vergara, Maria V; Vidal-Martinez, Guadalupe; Huaman, Mariluz V Vilchez; Vollaro, Caroline; Wagner, Kevin M; Wiese, Andrew D; Wilkerson, Sara; Zai, Gwyneth; Zappa, Luz M; Cruz, Vanessa Zavala; Zepeda-Burgos, Raquel M; Zoghbi, Anthony W; Albuquerque, Natalia G; Alexandria, Raissa; Alves, Gilberto S; Alves-Pereira, Raíza; Artiga, Larissa MS; Azevedo, Julianna P; Barbosa, Izabela G; Bortoncello, Cristiane F; Cappi, Carolina; Carneiro, Beatriz A; Cervone, Flávia; Christo, Renan B; Costa, Daniel LC; Cupertino, Fernanda; de Mathis, Maria Alice; de Menezes, Gabriela B; Dib, Luna; do Rosário, Maria Conceição; Dreher, Carolina B; Félix-da-Silva, Carina; Ferrão, Ygor A; Ferreira, Gabriela M; Ferreira, Luana C; Fontenelle, Leonardo F; Frota, Gabriel A; Gil, Maria Luiza W; Guarinon, Izabela G; Hoexter, Marcelo Q; Hounie, Ana G; Lima, Monicke O; Martinho, Ariane F; Mendes, Thays; Merces, Jamile VR; Miguel, Euripedes C; Muniz, Amelia; Oliveira, Beatriz SR; Passinho, Jhule S; Quarantini, Lucas C; Quarantini-Alvim, Yana; Ramos, Vanessa R; Sampaio, Aline S; Saraiva, Leonardo C; Sater, Pedro; Shavitt, Roseli G; Silva, Otavio AFS; Soares, Mirelly; Souza, Victor S; Stumpf, Bárbara P; Tavares, Bruna
Storch, Eric A; McCarty, Ryan J; Zehavi, Maya; Ahmad, Mahnoor; Cruz, Vanessa Zavala; Berrones, Dayan; Muñoz, Josselyn S; Obando, Diana; Rodriguez Barajas, Servando; Frederick, Renee M; Anderberg, Jacey L; Moore, Hannah C; Ochoa-Panaifo, Marcos E; Martinez Mallen, Mayra C; Onyeka, Ogechi C; Wiese, Andrew D; Sagarnaga, Melisa N; McGuire, Joseph F; Ferrão, Ygor Arzeno; Latin American Trans-Ancestry INitiative for OCD genomics (LATINO); Brazilian Obsessive-Compulsive Spectrum Disorder Working Group (GTTOC); Goodman, Wayne K; Crowley, James J
abstract
Efficient and accurate screening tools are crucial for improving early identification and treatment outcomes among individuals with obsessive-compulsive disorder (OCD). This study evaluated the sensitivity and specificity of two OCD screening measures: the Obsessive-Compulsive Inventory-4 (OCI-4) and the Florida Obsessive-Compulsive Inventory-II (FOCI-II) severity scale. The measures were administered in a large transnational sample of Spanish speaking Latin American adults (N = 1696) with elevated obsessive-compulsive symptomatology. Participants completed diagnostic interviews (MINI and Y-BOCS) and self-report assessments across 23 sites in 11 countries. Both measures significantly distinguished OCD from non-OCD cases, with the FOCI-II demonstrating somewhat better predictive performance (AUC = .79) compared to the OCI-4 (AUC = .69). A score of 7 or greater for both the OCI-4 (64 % sensitivity, 66 % specificity) and FOCI-II severity scale (74 % sensitivity, 70 % specificity) were found to be the most appropriate cutoffs across the overall sample. Findings provide some support in the use of both tools in clinical and research contexts, with some comparative benefits of the FOCI-II.
