The structure, redox chemistry and motor neuron toxicity of heterodimeric zinc-deficient SOD1-implications for the toxic gain of function observed in ALS Article

Streltsov, Victor A, Ganio, Katherine E, Nuttall, Stewart D et al. (2025). The structure, redox chemistry and motor neuron toxicity of heterodimeric zinc-deficient SOD1-implications for the toxic gain of function observed in ALS . 217 10.1016/j.nbd.2025.107189

cited authors

  • Streltsov, Victor A; Ganio, Katherine E; Nuttall, Stewart D; Hernandez, J Andres; Dennys, Cassandra N; Crouch, Peter J; Estevez, Alvaro G; Franco, Maria Clara; Beckman, Joseph S; Roberts, Blaine R

authors

publication date

  • December 1, 2025

keywords

  • AMYOTROPHIC-LATERAL-SCLEROSIS
  • Amyotrophic lateral sclerosis
  • COORDINATION
  • COPPER
  • HUMAN SUPEROXIDE-DISMUTASE
  • Life Sciences & Biomedicine
  • MECHANISM
  • MOTONEURON DEATH
  • NITRIC-OXIDE
  • Neurosciences
  • Neurosciences & Neurology
  • PROTEIN
  • Protein engineering
  • SOD1
  • Science & Technology
  • Superoxide dismutase
  • WILD-TYPE

Digital Object Identifier (DOI)

publisher

  • ELSEVIER

volume

  • 217