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PANK2-mediated de novo CoA synthesis is required for metabolic switching to fatty acid oxidation.
Preprint
Overview
Research
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Overview
cited authors
Nordlie, Sandra M; Schafer, Robert; Rauckhorst, Adam; Santos-Exposito, Ana M; Prieto-Rodriguez, Andres; Wilson, Bryce A; Evans, Idil A; Hadziamehtovic, Una; Nowlen, Frances; Santos-OcaƱa, Carlos; Taylor, Eric B; Kruer, Michael C; Padilla-Lopez, Sergio
authors
Rauckhorst, Adam
publication date
November 18, 2025
webpage
https://www.ncbi.nlm.nih.gov/pubmed/41279021
Research
keywords
Acetyl-CoA
Coenzyme A
Fatty Acid Oxidation
Metabolism
Neurodegenerative disease
Identifiers
Digital Object Identifier (DOI)
https://doi.org/10.1101/2025.10.07.680981