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Inhalable Advanced Co-Spray Dried Microparticles/Nanoparticles of a Novel RhoA/Rho Kinase Inhibitor with Lung Surfactant Biomimetic Phospholipids for Targeted Lung Delivery Article

Ruiz, Victor H, Encinas-Basurto, David, Ortega-Alarcon, Neftali et al. (2024). Inhalable Advanced Co-Spray Dried Microparticles/Nanoparticles of a Novel RhoA/Rho Kinase Inhibitor with Lung Surfactant Biomimetic Phospholipids for Targeted Lung Delivery . 7(10), 3241-3254. 10.1021/acsptsci.4c00432

cited authors

  • Ruiz, Victor H; Encinas-Basurto, David; Ortega-Alarcon, Neftali; Eedara, Basanth Babu; Fineman, Jeffrey R; Black, Stephen M; Mansour, Heidi M

authors

publication date

  • October 3, 2024

keywords

  • AEROSOL DISPERSION PERFORMANCE
  • CELL-CULTURE
  • Chemistry, Medicinal
  • DESIGN
  • DIPALMITOYLPHOSPHATIDYLCHOLINE DPPC
  • FASUDIL
  • INHALATION
  • Life Sciences & Biomedicine
  • PARTICLES
  • PHYSICOCHEMICAL CHARACTERIZATION
  • POWDERS
  • PULMONARY ARTERIAL-HYPERTENSION
  • Pharmacology & Pharmacy
  • Science & Technology
  • air-liquid interface
  • drypowder inhalers (DPIs)
  • fasudil monohydrochloride
  • in vitro aerosol dispersion
  • in vitro drug release
  • in vitro franz cell diffusion
  • in vitro human cell culture
  • proliposomes
  • pulmonary hypertension (PH)
  • sustained drug release

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 3241

end page

  • 3254

volume

  • 7

issue

  • 10