Sequence plasticity in the antigen-binding site of a therapeutic anti-HER2 antibody Article

Gerstner, RB, Carter, P, Lowman, HB. (2002). Sequence plasticity in the antigen-binding site of a therapeutic anti-HER2 antibody . JOURNAL OF MOLECULAR BIOLOGY, 321(5), 851-862. 10.1016/S0022-2836(02)00677-0

cited authors

  • Gerstner, RB; Carter, P; Lowman, HB

sustainable development goals

authors

publication date

  • August 30, 2002

published in

keywords

  • AFFINITY
  • ANTI-P185HER2 ANTIBODY
  • Biochemistry & Molecular Biology
  • COMPLEMENTARITY-DETERMINING REGIONS
  • EPITOPES
  • EVOLUTION
  • FAB
  • HUMAN-BREAST
  • Life Sciences & Biomedicine
  • MONOCLONAL-ANTIBODY
  • PHAGE DISPLAY
  • SELECTION
  • Science & Technology
  • affinity maturation
  • erb B2
  • phage display
  • trastuzumab
  • tumor antigen

Digital Object Identifier (DOI)

publisher

  • ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD

start page

  • 851

end page

  • 862

volume

  • 321

issue

  • 5