Casein kinase activity during early development of loach (Misgurnus fossilis L.) Article

Zemskov, EA, Abramova, EB, Klyachko, OS et al. (1998). Casein kinase activity during early development of loach (Misgurnus fossilis L.) . 25(2), 182-185.

cited authors

  • Zemskov, EA; Abramova, EB; Klyachko, OS; Ozernyuk, ND; Mikhailov, VS

authors

abstract

  • In the course of embryonic development of the loach, from the 8-cell stage to the stage before hatching, the total casein kinase activity of cell extracts increased more than twice. Both casein kinase II (CK II) and casein kinase I (CK I) were present in the embryos. Part of CK II was in a masked (inactive) state, and the ratio of masked to unmasked forms of the enzyme increased during embryogenesis. A part of the unmasked CK II was incorporated in macromolecular complexes that prevent its inhibition by heparin, but allow its catalytic function. The proportion of CK II that didn't interact with heparin increased by the end of embryogenesis. Chromatography of DEAE-sorbite sell-extracts removes the factors protecting CK II against inhibition by heparin. © 1998 MAK Hayka/Interperiodica Publishing.

publication date

  • December 1, 1998

start page

  • 182

end page

  • 185

volume

  • 25

issue

  • 2